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Bon-Kyoung Koo
Bon-Kyoung Koo
Institute of Molecular Biotechnology (IMBA) - The Austrian Academy of Sciences
Verified email at imba.oeaw.ac.at - Homepage
Title
Cited by
Cited by
Year
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
G Schwank, BK Koo, V Sasselli, JF Dekkers, I Heo, T Demircan, N Sasaki, ...
Cell stem cell 13 (6), 653-658, 2013
13192013
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ...
Nature 476 (7360), 293-297, 2011
12002011
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ...
Nature 488 (7413), 665-669, 2012
7992012
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers
J Muńoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ...
The EMBO journal 31 (14), 3079-3091, 2012
6912012
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ...
Nature medicine 23 (12), 1424-1435, 2017
6622017
Human organoids: model systems for human biology and medicine
J Kim, BK Koo, JA Knoblich
Nature Reviews Molecular Cell Biology 21 (10), 571-584, 2020
4902020
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium
DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ...
Cell 155 (2), 357-368, 2013
4192013
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
L Broutier, A Andersson-Rolf, CJ Hindley, SF Boj, H Clevers, BK Koo, ...
Nature protocols 11 (9), 1724-1743, 2016
4082016
Modeling mouse and human development using organoid cultures
M Huch, BK Koo
Development 142 (18), 3113-3125, 2015
3592015
Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium
MY Turco, L Gardner, J Hughes, T Cindrova-Davies, MJ Gomez, L Farrell, ...
Nature cell biology 19 (5), 568-577, 2017
3052017
Controlled gene expression in primary Lgr5 organoid cultures
BK Koo, DE Stange, T Sato, W Karthaus, HF Farin, M Huch, JH Van Es, ...
Nature methods 9 (1), 81-83, 2012
3032012
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch
BK Koo, HS Lim, R Song, MJ Yoon, KJ Yoon, JS Moon, YW Kim, M Kwon, ...
Oxford University Press for The Company of Biologists Limited 132 (15), 3459 …, 2005
2622005
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
JH van Es, A Haegebarth, P Kujala, S Itzkovitz, BK Koo, SF Boj, J Korving, ...
Molecular and cellular biology 32 (10), 1918-1927, 2012
2492012
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts
J Schuijers, JP Junker, M Mokry, P Hatzis, BK Koo, V Sasselli, ...
Cell stem cell 16 (2), 158-170, 2015
2202015
A crucial role of WW45 in developing epithelial tissues in the mouse
JH Lee, TS Kim, TH Yang, BK Koo, SP Oh, KP Lee, HJ Oh, SH Lee, ...
The EMBO journal 27 (8), 1231-1242, 2008
2162008
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response
J Heijmans, JFL de Jeude, BK Koo, SL Rosekrans, MCB Wielenga, ...
Cell reports 3 (4), 1128-1139, 2013
2062013
Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells
KJ Yoon, BK Koo, SK Im, HW Jeong, J Ghim, M Kwon, JS Moon, T Miyata, ...
Neuron 58 (4), 519-531, 2008
1902008
Defective Notch activation in microenvironment leads to myeloproliferative disease
YW Kim, BK Koo, HW Jeong, MJ Yoon, R Song, J Shin, DC Jeong, ...
Blood, The Journal of the American Society of Hematology 112 (12), 4628-4638, 2008
1672008
Receptor activator of NF-κB ligand regulates the proliferation of mammary epithelial cells via Id2
NS Kim, HJ Kim, BK Koo, MC Kwon, YW Kim, Y Cho, Y Yokota, ...
Molecular and cellular biology 26 (3), 1002-1013, 2006
1622006
DNA methylation and transcription patterns in intestinal epithelial cells from pediatric patients with inflammatory bowel diseases differentiate disease subtypes and associate …
KJ Howell, J Kraiczy, KM Nayak, M Gasparetto, A Ross, C Lee, TN Mak, ...
Gastroenterology 154 (3), 585-598, 2018
1602018
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