| (α-Monofluoroalkyl) phosphonates: a class of isoacidic and “tunable” mimics of biological phosphates DB Berkowitz, M Bose Journal of Fluorine Chemistry 112 (1), 13-33, 2001 | 147 | 2001 |
| Ready access to fluorinated phosphonate mimics of secondary phosphates. Synthesis of the (α, α-difluoroalkyl) phosphonate analogues of L-phosphoserine, L-phosphoallothreonine … DB Berkowitz, MJ Eggen, Q Shen, RK Shoemaker The Journal of organic chemistry 61 (14), 4666-4675, 1996 | 141 | 1996 |
| α-Fluorinated phosphonates as substrate mimics for glucose 6-phosphate dehydrogenase: The CHF stereochemistry matters DB Berkowitz, M Bose, TJ Pfannenstiel, T Doukov The Journal of organic chemistry 65 (15), 4498-4508, 2000 | 134 | 2000 |
| Enzyme-assisted asymmetric total synthesis of (−)-podophyllotoxin and (−)-picropodophyllin DB Berkowitz, S Choi, JH Maeng The Journal of organic chemistry 65 (3), 847-860, 2000 | 112 | 2000 |
| Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens JA Friest, Y Maezato, S Broussy, P Blum, DB Berkowitz Journal of the American Chemical Society 132 (17), 5930-5931, 2010 | 106 | 2010 |
| Use of fluorinated functionality in enzyme inhibitor development: Mechanistic and analytical advantages DB Berkowitz, KR Karukurichi, R de la Salud-Bea, DL Nelson, ... Journal of fluorine chemistry 129 (9), 731-742, 2008 | 103 | 2008 |
| Synthesis of (. alpha.,. alpha.-difluoroalkyl) phosphonates by displacement of primary triflates DB Berkowitz, MJ Eggen, Q Shen, DG Sloss The Journal of Organic Chemistry 58 (23), 6174-6176, 1993 | 102 | 1993 |
| Topoisomerase II− drug interaction domains: Identification of substituents on etoposide that interact with the enzyme AM Wilstermann, RP Bender, M Godfrey, S Choi, C Anklin, DB Berkowitz, ... Biochemistry 46 (28), 8217-8225, 2007 | 100 | 2007 |
| Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: ethanol as tunable nicotinamide reductant S Broussy, RW Cheloha, DB Berkowitz Organic letters 11 (2), 305-308, 2009 | 99 | 2009 |
| A route to artificial glycoconjugates and oligosaccharides via enzymically resolved glycals: dramatic effects of the handedness of the sugar domain upon the properties of an … DB Berkowitz, SJ Danishefsky, GK Schulte Journal of the American Chemical Society 114 (12), 4518-4529, 1992 | 96 | 1992 |
| Following an ISES lead: The first examples of asymmetric Ni (0)-mediated allylic amination DB Berkowitz, G Maiti Organic letters 6 (16), 2661-2664, 2004 | 91 | 2004 |
| Synthesis of the (α, α-difluoroalkyl) phosphonate analogue of phosphoserine DB Berkowitz, Q Shen, JH Maeng Tetrahedron letters 35 (35), 6445-6448, 1994 | 91 | 1994 |
| Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by rather than by phosphoranes NJ Baxter, MW Bowler, T Alizadeh, MJ Cliff, AM Hounslow, B Wu, ... Proceedings of the National Academy of Sciences 107 (10), 4555-4560, 2010 | 88 | 2010 |
| Enantiomerically Enriched. alpha.-Methyl Amino Acids. Use of an Acyclic, Chiral Alanine-Derived Dianion with a High Diastereofacial Bias DB Berkowitz, MK Smith The Journal of organic chemistry 60 (5), 1233-1238, 1995 | 80 | 1995 |
| Diallyl (Lithiodifluoromethyl) phosphonate: A new reagent for the introduction of the (difluoromethylene) phosphonate functionality DB Berkowitz, DG Sloss The Journal of Organic Chemistry 60 (21), 7047-7050, 1995 | 79 | 1995 |
| The α, α-difluorinated phosphonate L-pSer-analogue: an accessible chemical tool for studying kinase-dependent signal transduction K Panigrahi, MJ Eggen, JH Maeng, Q Shen, DB Berkowitz Chemistry & biology 16 (9), 928-936, 2009 | 78 | 2009 |
| Exploiting enzymatic dynamic reductive kinetic resolution (DYRKR) in stereocontrolled synthesis GA Applegate, DB Berkowitz Advanced synthesis & catalysis 357 (8), 1619-1632, 2015 | 77 | 2015 |
| α-Vinylic amino acids: occurrence, asymmetric synthesis, and biochemical mechanisms DB Berkowitz, BD Charette, KR Karukurichi, JM McFadden Tetrahedron: Asymmetry 17 (6), 869-882, 2006 | 75 | 2006 |
| Formal. alpha.-vinylation of amino acids. Use of a new benzeneselenolate equivalent ML Pedersen, DB Berkowitz The Journal of Organic Chemistry 58 (25), 6966-6975, 1993 | 74 | 1993 |
| Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis M Dasgupta, D Budday, SHP De Oliveira, P Madzelan, ... Proceedings of the National Academy of Sciences 116 (51), 25634-25640, 2019 | 61 | 2019 |
