(α-Monofluoroalkyl) phosphonates: a class of isoacidic and “tunable” mimics of biological phosphates DB Berkowitz, M Bose
Journal of Fluorine Chemistry 112 (1), 13-33, 2001
147 2001 Ready access to fluorinated phosphonate mimics of secondary phosphates. Synthesis of the (α, α-difluoroalkyl) phosphonate analogues of L-phosphoserine, L-phosphoallothreonine … DB Berkowitz, MJ Eggen, Q Shen, RK Shoemaker
The Journal of organic chemistry 61 (14), 4666-4675, 1996
141 1996 α-Fluorinated phosphonates as substrate mimics for glucose 6-phosphate dehydrogenase: The CHF stereochemistry matters DB Berkowitz, M Bose, TJ Pfannenstiel, T Doukov
The Journal of organic chemistry 65 (15), 4498-4508, 2000
134 2000 Enzyme-assisted asymmetric total synthesis of (−)-podophyllotoxin and (−)-picropodophyllin DB Berkowitz, S Choi, JH Maeng
The Journal of organic chemistry 65 (3), 847-860, 2000
112 2000 Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S )-Profens JA Friest, Y Maezato, S Broussy, P Blum, DB Berkowitz
Journal of the American Chemical Society 132 (17), 5930-5931, 2010
107 2010 Use of fluorinated functionality in enzyme inhibitor development: Mechanistic and analytical advantages DB Berkowitz, KR Karukurichi, R de la Salud-Bea, DL Nelson, ...
Journal of fluorine chemistry 129 (9), 731-742, 2008
103 2008 Synthesis of (. alpha.,. alpha.-difluoroalkyl) phosphonates by displacement of primary triflates DB Berkowitz, MJ Eggen, Q Shen, DG Sloss
The Journal of Organic Chemistry 58 (23), 6174-6176, 1993
102 1993 Topoisomerase II− drug interaction domains: Identification of substituents on etoposide that interact with the enzyme AM Wilstermann, RP Bender, M Godfrey, S Choi, C Anklin, DB Berkowitz, ...
Biochemistry 46 (28), 8217-8225, 2007
100 2007 Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: ethanol as tunable nicotinamide reductant S Broussy, RW Cheloha, DB Berkowitz
Organic letters 11 (2), 305-308, 2009
99 2009 A route to artificial glycoconjugates and oligosaccharides via enzymically resolved glycals: dramatic effects of the handedness of the sugar domain upon the properties of an … DB Berkowitz, SJ Danishefsky, GK Schulte
Journal of the American Chemical Society 114 (12), 4518-4529, 1992
96 1992 Following an ISES lead: The first examples of asymmetric Ni (0)-mediated allylic amination DB Berkowitz, G Maiti
Organic letters 6 (16), 2661-2664, 2004
91 2004 Synthesis of the (α, α-difluoroalkyl) phosphonate analogue of phosphoserine DB Berkowitz, Q Shen, JH Maeng
Tetrahedron letters 35 (35), 6445-6448, 1994
91 1994 Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by rather than by phosphoranes NJ Baxter, MW Bowler, T Alizadeh, MJ Cliff, AM Hounslow, B Wu, ...
Proceedings of the National Academy of Sciences 107 (10), 4555-4560, 2010
88 2010 Enantiomerically Enriched. alpha.-Methyl Amino Acids. Use of an Acyclic, Chiral Alanine-Derived Dianion with a High Diastereofacial Bias DB Berkowitz, MK Smith
The Journal of organic chemistry 60 (5), 1233-1238, 1995
81 1995 Diallyl (Lithiodifluoromethyl) phosphonate: A new reagent for the introduction of the (difluoromethylene) phosphonate functionality DB Berkowitz, DG Sloss
The Journal of Organic Chemistry 60 (21), 7047-7050, 1995
79 1995 Exploiting enzymatic dynamic reductive kinetic resolution (DYRKR) in stereocontrolled synthesis GA Applegate, DB Berkowitz
Advanced synthesis & catalysis 357 (8), 1619-1632, 2015
78 2015 The α, α-difluorinated phosphonate L-pSer-analogue: an accessible chemical tool for studying kinase-dependent signal transduction K Panigrahi, MJ Eggen, JH Maeng, Q Shen, DB Berkowitz
Chemistry & biology 16 (9), 928-936, 2009
78 2009 α-Vinylic amino acids: occurrence, asymmetric synthesis, and biochemical mechanisms DB Berkowitz, BD Charette, KR Karukurichi, JM McFadden
Tetrahedron: Asymmetry 17 (6), 869-882, 2006
75 2006 Formal. alpha.-vinylation of amino acids. Use of a new benzeneselenolate equivalent ML Pedersen, DB Berkowitz
The Journal of Organic Chemistry 58 (25), 6966-6975, 1993
75 1993 Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis M Dasgupta, D Budday, SHP De Oliveira, P Madzelan, ...
Proceedings of the National Academy of Sciences 116 (51), 25634-25640, 2019
61 2019