| A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations LM Raamsdonk, B Teusink, D Broadhurst, N Zhang, A Hayes, MC Walsh, ... Nature biotechnology 19 (1), 45-50, 2001 | 1338 | 2001 |
| A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419-425, 2013 | 1199 | 2013 |
| Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry B Teusink, J Passarge, CA Reijenga, E Esgalhado, CC Van der Weijden, ... European journal of biochemistry 267 (17), 5313-5329, 2000 | 913 | 2000 |
| The evolution of molecular biology into systems biology HV Westerhoff, BO Palsson Nature biotechnology 22 (10), 1249-1252, 2004 | 772 | 2004 |
| The nature of systems biology FJ Bruggeman, HV Westerhoff TRENDS in Microbiology 15 (1), 45-50, 2007 | 740 | 2007 |
| Quantification of the contribution of various steps to the control of mitochondrial respiration. AK Groen, RJ Wanders, HV Westerhoff, R Van der Meer, JM Tager Journal of Biological Chemistry 257 (6), 2754-2757, 1982 | 736 | 1982 |
| A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ... Nature biotechnology 26 (10), 1155-1160, 2008 | 692 | 2008 |
| Thermodynamics and control of biological free-energy transduction HV Westerhoff, K Van Dam (No Title), 1987 | 609 | 1987 |
| Cancer: a systems biology disease JJ Hornberg, FJ Bruggeman, HV Westerhoff, J Lankelma Biosystems 83 (2-3), 81-90, 2006 | 534 | 2006 |
| Untangling the wires: a strategy to trace functional interactions in signaling and gene networks BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ... Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002 | 501 | 2002 |
| Transcriptome meets metabolome: hierarchical and metabolic regulation of the glycolytic pathway BH ter Kuile, HV Westerhoff FEBS letters 500 (3), 169-171, 2001 | 435 | 2001 |
| Magainins and the disruption of membrane-linked free-energy transduction. HV Westerhoff, D Juretić, RW Hendler, M Zasloff Proceedings of the National Academy of Sciences 86 (17), 6597-6601, 1989 | 413 | 1989 |
| The Glycolytic Flux in Escherichia coli Is Controlled by the Demand for ATP BJ Koebmann, HV Westerhoff, JL Snoep, D Nilsson, PR Jensen Journal of bacteriology 184 (14), 3909-3916, 2002 | 409 | 2002 |
| Movement of fatty acids, fatty acid analogs, and bile acids across phospholipid bilayers F Kamp, JA Hamilton Biochemistry 32 (41), 11074-11085, 1993 | 396 | 1993 |
| The danger of metabolic pathways with turbo design B Teusink, MC Walsh, K van Dam, HV Westerhoff Trends in biochemical sciences 23 (5), 162-169, 1998 | 301 | 1998 |
| Cytosolic triglycerides and oxidative stress in central obesity: the missing link between excessive atherosclerosis, endothelial dysfunction, and β-cell failure? SJL Bakker, RG IJzerman, T Teerlink, HV Westerhoff, ROB Gans, ... Atherosclerosis 148 (1), 17-21, 2000 | 296 | 2000 |
| Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes BM Bakker, PAM Michels, FR Opperdoes, HV Westerhoff Journal of Biological Chemistry 272 (6), 3207-3215, 1997 | 291 | 1997 |
| Why cytoplasmic signalling proteins should be recruited to cell membranes BN Kholodenko, JB Hoek, HV Westerhoff Trends in cell biology 10 (5), 173-178, 2000 | 284 | 2000 |
| Systems biology: philosophical foundations F Boogerd, FJ Bruggeman, JHS Hofmeyr, HV Westerhoff Elsevier, 2007 | 280 | 2007 |
| The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels P Daran-Lapujade, S Rossell, WM van Gulik, MAH Luttik, MJL de Groot, ... Proceedings of the National Academy of Sciences 104 (40), 15753-15758, 2007 | 276 | 2007 |
Snoep JLStellenbosch University; Manchester University; Vrije Universiteit AmsterdamVerified email at sun.ac.za
