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Chiara Brignole
Chiara Brignole
Laboratory of Experimental Therapy in Oncology, IRCCS Istituto Giannina Gaslini
Geverifieerd e-mailadres voor gaslini.org
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Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease
M Bacci, A Capobianco, A Monno, L Cottone, F Di Puppo, B Camisa, ...
The American journal of pathology 175 (2), 547-556, 2009
4102009
Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy
F Pastorino, C Brignole, D Marimpietri, M Cilli, C Gambini, D Ribatti, ...
Cancer research 63 (21), 7400-7409, 2003
3972003
Targeting liposomal chemotherapy via both tumor cell–specific and tumor vasculature–specific ligands potentiates therapeutic efficacy
F Pastorino, C Brignole, D Di Paolo, B Nico, A Pezzolo, D Marimpietri, ...
Cancer research 66 (20), 10073-10082, 2006
2902006
Doxorubicin-loaded Fab′ fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice
F Pastorino, C Brignole, D Marimpietri, P Sapra, EH Moase, TM Allen, ...
Cancer research 63 (1), 86-92, 2003
2092003
Effect of bortezomib on human neuroblastoma cell growth, apoptosis, and angiogenesis
C Brignole, D Marimpietri, F Pastorino, B Nico, D Di Paolo, M Cioni, ...
Journal of the National Cancer Institute 98 (16), 1142-1157, 2006
1572006
Targeting macrophages as a potential therapeutic intervention: impact on inflammatory diseases and cancer
M Ponzoni, F Pastorino, D Di Paolo, P Perri, C Brignole
International journal of molecular sciences 19 (7), 1953, 2018
1532018
Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models
F Pastorino, C Brignole, D Marimpietri, G Pagnan, A Morando, D Ribatti, ...
Clinical cancer research 9 (12), 4595-4605, 2003
1172003
Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin
F Pastorino, D Di Paolo, F Piccardi, B Nico, D Ribatti, A Daga, G Baio, ...
Clinical Cancer Research 14 (22), 7320-7329, 2008
1092008
A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects
F Piaggio, V Kondylis, F Pastorino, D Di Paolo, P Perri, I Cossu, F Schorn, ...
Journal of Controlled Release 223, 165-177, 2016
1052016
Expression and methylation of CASP8 in neuroblastoma: Identification of a promoter region
B Banelli, I Casciano, M Croce, AD Vinci, I Gelvi, G Pagnan, C Brignole, ...
Nature medicine 8 (12), 1333-1335, 2002
1022002
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
M Loi, S Marchiò, P Becherini, D Di Paolo, M Soster, F Curnis, C Brignole, ...
Journal of controlled release 145 (1), 66-73, 2010
912010
Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis
D Marimpietri, C Brignole, B Nico, F Pastorino, A Pezzolo, F Piccardi, ...
Clinical Cancer Research 13 (13), 3977-3988, 2007
882007
Immune cell–mediated antitumor activities of GD2-targeted liposomal c-myb antisense oligonucleotides containing CpG motifs
C Brignole, F Pastorino, D Marimpietri, G Pagnan, A Pistorio, TM Allen, ...
Journal of the National Cancer Institute 96 (15), 1171-1180, 2004
872004
Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma
C Brignole, D Marimpietri, DD Paolo, P Perri, F Morandi, F Pastorino, ...
Cancer research 70 (23), 9816-9826, 2010
862010
Angiogenesis in neuroblastoma
D Ribatti, D Marimpietri, F Pastorino, C Brignole, B Nico, A Vacca, ...
Annals of the New York Academy of Sciences 1028 (1), 133-142, 2004
812004
Recent advances in the developmental origin of neuroblastoma: an overview
M Ponzoni, T Bachetti, MV Corrias, C Brignole, F Pastorino, E Calarco, ...
Journal of Experimental & Clinical Cancer Research 41 (1), 92, 2022
802022
Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK
D Di Paolo, C Brignole, F Pastorino, R Carosio, A Zorzoli, M Rossi, M Loi, ...
Molecular Therapy 19 (6), 1131-1140, 2011
782011
Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma
D Di Paolo, C Ambrogio, F Pastorino, C Brignole, C Martinengo, ...
Molecular Therapy 19 (12), 2201-2212, 2011
762011
In vivo angiogenic activity of neuroblastoma correlates with MYCN oncogene overexpression
D Ribatti, L Raffaghello, F Pastorino, B Nico, C Brignole, A Vacca, ...
International journal of cancer 102 (4), 351-354, 2002
722002
PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma
T Bachetti, D Di Paolo, S Di Lascio, V Mirisola, C Brignole, M Bellotti, ...
PloS one 5 (10), e13108, 2010
702010
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Artikelen 1–20