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Rafaela Salgado Ferreira
Rafaela Salgado Ferreira
Biochemistry and Immunology Department, Universidade Federal de Minas Gerais
Geverifieerd e-mailadres voor icb.ufmg.br
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Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
2942016
Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors
RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ...
Journal of medicinal chemistry 53 (13), 4891-4905, 2010
2682010
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease
A Jadhav, RS Ferreira, C Klumpp, BT Mott, CP Austin, J Inglese, ...
Journal of medicinal chemistry 53 (1), 37-51, 2010
2572010
Docking and chemoinformatic screens for new ligands and targets
P Kolb, RS Ferreira, JJ Irwin, BK Shoichet
Current opinion in biotechnology 20 (4), 429-436, 2009
2332009
Two approaches to discovering and developing new drugs for Chagas disease
JH McKerrow, PS Doyle, JC Engel, LM Podust, SA Robertson, R Ferreira, ...
Memórias do Instituto Oswaldo Cruz 104, 263-269, 2009
2192009
Strongly coupling a cavity to inhomogeneous ensembles of emitters: Potential for long-lived solid-state quantum memories
I Diniz, S Portolan, R Ferreira, JM Gérard, P Bertet, A Auffeves
Physical Review A 84 (6), 063810, 2011
2002011
Identification and optimization of inhibitors of trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB
BT Mott, RS Ferreira, A Simeonov, A Jadhav, KKH Ang, W Leister, M Shen, ...
Journal of medicinal chemistry 53 (1), 52-60, 2010
1652010
Integrating molecular docking and molecular dynamics simulations
LHS Santos, RS Ferreira, ER Caffarena
Docking screens for drug discovery, 13-34, 2019
1392019
Docking for fragment inhibitors of AmpC β-lactamase
DG Teotico, K Babaoglu, GJ Rocklin, RS Ferreira, AM Giannetti, ...
Proceedings of the National Academy of Sciences 106 (18), 7455-7460, 2009
1322009
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation
MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ...
European Journal of Medicinal Chemistry 86, 48-59, 2014
1152014
Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases
C Bryant, ID Kerr, M Debnath, KKH Ang, J Ratnam, RS Ferreira, ...
Bioorganic & medicinal chemistry letters 19 (21), 6218-6221, 2009
992009
Synthesis, Biological Evaluation, and Structure–Activity Relationships of Potent Noncovalent and Nonpeptidic Cruzain Inhibitors as Anti-Trypanosoma cruzi Agents
RS Ferreira, MA Dessoy, I Pauli, ML Souza, R Krogh, AIL Sales, G Oliva, ...
Journal of medicinal chemistry 57 (6), 2380-2392, 2014
952014
Divergent modes of enzyme inhibition in a homologous structure− activity series
RS Ferreira, C Bryant, KKH Ang, JH McKerrow, BK Shoichet, AR Renslo
Journal of Medicinal Chemistry 52 (16), 5005-5008, 2009
892009
Antidepressant-like effect of terpineol in an inflammatory model of depression: involvement of the cannabinoid system and D2 dopamine receptor
G Vieira, J Cavalli, ECD Gonçalves, SFP Braga, RS Ferreira, ARS Santos, ...
Biomolecules 10 (5), 792, 2020
742020
Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice
DRM Moreira, SPM Costa, MZ Hernandes, MM Rabello, ...
Journal of Medicinal Chemistry 55 (24), 10918-10936, 2012
722012
Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni …
NC Fonseca, LF da Cruz, F da Silva Villela, GA do Nascimento Pereira, ...
Antimicrobial Agents and Chemotherapy 59 (5), 2666-2677, 2015
702015
Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma Cruzi Cruzain
JWP Espíndola, MV de Oliveira Cardoso, GB de Oliveira Filho, ...
European Journal of Medicinal Chemistry 101, 818-835, 2015
682015
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents
MZ Hernandes, MM Rabello, ACL Leite, MVO Cardoso, DRM Moreira, ...
Bioorganic & Medicinal Chemistry 18 (22), 7826-7835, 2010
682010
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death
DRM Moreira, ADT de Oliveira, PAT de Moraes Gomes, CA de Simone, ...
European journal of medicinal chemistry 75, 467-478, 2014
672014
Synthesis and leishmanicidal activity of eugenol derivatives bearing 1, 2, 3-triazole functionalities
RR Teixeira, PAR Gazolla, AM da Silva, MPG Borsodi, BR Bergmann, ...
European Journal of Medicinal Chemistry 146, 274-286, 2018
662018
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