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Filippos Porichis
Filippos Porichis
Director of International Programs at the Ragon Institute.- Instructor in Medicine at Harvard
Geverifieerd e-mailadres voor mgh.harvard.edu - Homepage
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Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ...
Nature medicine 16 (10), 1147-1151, 2010
5832010
IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells
MA Brockman, DS Kwon, DP Tighe, DF Pavlik, PC Rosato, J Sela, ...
Blood, The Journal of the American Society of Hematology 114 (2), 346-356, 2009
3272009
Sex differences in plasmacytoid dendritic cell levels of IRF5 drive higher IFN-α production in women
M Griesbeck, S Ziegler, S Laffont, N Smith, L Chauveau, P Tomezsko, ...
The Journal of Immunology 195 (11), 5327-5336, 2015
2182015
Single-cell characterization of viral translation-competent reservoirs in HIV-infected individuals
AE Baxter, J Niessl, R Fromentin, J Richard, F Porichis, R Charlebois, ...
Cell host & microbe 20 (3), 368-380, 2016
2022016
Responsiveness of HIV-specific CD4 T cells to PD-1 blockade
F Porichis, DS Kwon, J Zupkosky, DP Tighe, A McMullen, MA Brockman, ...
Blood, The Journal of the American Society of Hematology 118 (4), 965-974, 2011
1872011
Role of PD-1 in HIV pathogenesis and as target for therapy
F Porichis, DE Kaufmann
Current HIV/AIDS Reports 9, 81-90, 2012
1782012
Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells
B Youngblood, A Noto, F Porichis, RS Akondy, ZM Ndhlovu, JW Austin, ...
The Journal of Immunology 191 (2), 540-544, 2013
1702013
High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry
F Porichis, MG Hart, M Griesbeck, HL Everett, M Hassan, AE Baxter, ...
Nature communications 5 (1), 5641, 2014
1582014
HIV-specific CD4 T cells and immune control of viral replication
F Porichis, DE Kaufmann
Current Opinion in HIV and AIDS 6 (3), 174-180, 2011
1322011
Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10
M Rodríguez-García, F Porichis, OG de Jong, K Levi, TJ Diefenbach, ...
Journal of leukocyte biology 89 (4), 507-515, 2011
1302011
A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells
Z Vlata, F Porichis, G Tzanakakis, A Tsatsakis, E Krambovitis
Toxicology Letters 165 (3), 274-281, 2006
1042006
Immunization of HIV-1-infected persons with autologous dendritic cells transfected with mRNA encoding HIV-1 Gag and Nef: results of a randomized, placebo-controlled clinical trial
RT Gandhi, DS Kwon, EA Macklin, JR Shopis, AP McLean, N McBrine, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 71 (3), 246-253, 2016
892016
Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions
F Porichis, MG Hart, J Zupkosky, L Barblu, DS Kwon, A McMullen, ...
Journal of virology 88 (5), 2508-2518, 2014
802014
High-dimensional immunomonitoring models of HIV-1–specific CD8 T-cell responses accurately identify subjects achieving spontaneous viral control
ZM Ndhlovu, LB Chibnik, J Proudfoot, S Vine, A McMullen, K Cesa, ...
Blood, The Journal of the American Society of Hematology 121 (5), 801-811, 2013
732013
Immune checkpoint blockade restores HIV-specific CD4 T cell help for NK cells
F Porichis, MG Hart, A Massa, HL Everett, A Morou, J Richard, N Brassard, ...
The Journal of Immunology 201 (3), 971-981, 2018
672018
Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique
AE Baxter, J Niessl, R Fromentin, J Richard, F Porichis, M Massanella, ...
Nature protocols 12 (10), 2029-2049, 2017
662017
Circulating CXCR5+ CXCR3+ PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth
E Martin-Gayo, J Cronin, T Hickman, Z Ouyang, M Lindqvist, KE Kolb, ...
JCI insight 2 (2), 2017
602017
HIV controllers: a multifactorial phenotype of spontaneous viral suppression
J Thèze, LA Chakrabarti, B Vingert, F Porichis, DE Kaufmann
Clinical immunology 141 (1), 15-30, 2011
582011
CD4+ CD25+ Regulatory T Cells Impair HIV-1-Specific CD4 T Cell Responses by Upregulating Interleukin-10 Production in Monocytes
DS Kwon, M Angin, T Hongo, KM Law, J Johnson, F Porichis, MG Hart, ...
Journal of virology 86 (12), 6586-6594, 2012
482012
HIV entry inhibitors: a new generation of antiretroviral drugs
E Krambovitis, F Porichis, DA Spandidos
ACTA Pharmacologica Sinica 26 (10), 1165-1173, 2005
432005
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Artikelen 1–20