Lech Milroy
Lech Milroy
Milroy CMC consultancy
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Cited by
Modulators of protein–protein interactions
LG Milroy, TN Grossmann, S Hennig, L Brunsveld, C Ottmann
Chemical reviews 114 (9), 4695-4748, 2014
Metal‐free photocatalytic aerobic oxidation of thiols to disulfides in batch and continuous‐flow
A Talla, B Driessen, NJW Straathof, LG Milroy, L Brunsveld, V Hessel, ...
Advanced Synthesis & Catalysis 357 (10), 2180-2186, 2015
Supramolecular chemistry targeting proteins
S van Dun, C Ottmann, LG Milroy, L Brunsveld
Journal of the American Chemical Society 139 (40), 13960-13968, 2017
Stabilization of protein-protein interactions in drug discovery
SA Andrei, E Sijbesma, M Hann, J Davis, G O’Mahony, MWD Perry, ...
Expert opinion on drug discovery 12 (9), 925-940, 2017
Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR
LM Stevers, CV Lam, SFR Leysen, FA Meijer, DS van Scheppingen, ...
Proceedings of the National Academy of Sciences 113 (9), E1152-E1161, 2016
Synthesis and structure− activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin
R Tannert, LG Milroy, B Ellinger, TS Hu, HD Arndt, H Waldmann
Journal of the American Chemical Society 132 (9), 3063-3077, 2010
Batch and Flow Synthesis of Disulfides by Visible‐Light‐Induced TiO2 Photocatalysis
C Bottecchia, N Erdmann, PMA Tijssen, LG Milroy, L Brunsveld, V Hessel, ...
ChemSusChem 9 (14), 1781-1785, 2016
Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives
G Zinzalla, LG Milroy, SV Ley
Organic & Biomolecular Chemistry 4 (10), 1977-2002, 2006
Stabilization and inhibition of protein–protein interactions: The 14-3-3 case study
LG Milroy, L Brunsveld, C Ottmann
ACS chemical biology 8 (1), 27-35, 2013
A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit [8] uril and Dimeric Adapter Protein 14‐3‐3
PJ de Vink, JM Briels, T Schrader, LG Milroy, L Brunsveld, C Ottmann
Angewandte Chemie 129 (31), 9126-9130, 2017
Supramolecular control of cell adhesion via ferrocene–cucurbit [7] uril host–guest binding on gold surfaces
P Neirynck, J Brinkmann, Q An, DWJ van der Schaft, LG Milroy, ...
Chemical communications 49 (35), 3679-3681, 2013
Selective chemical imaging of static actin in live cells
LG Milroy, S Rizzo, A Calderon, B Ellinger, S Erdmann, J Mondry, ...
Journal of the American Chemical Society 134 (20), 8480-8486, 2012
Stabilizer‐Guided Inhibition of Protein–Protein Interactions
LG Milroy, M Bartel, MA Henen, S Leysen, JMC Adriaans, L Brunsveld, ...
Angewandte Chemie International Edition 54 (52), 15720-15724, 2015
Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
X Qi, F Loiseau, WL Chan, Y Yan, Z Wei, LG Milroy, RM Myers, SV Ley, ...
Journal of Biological Chemistry 286 (18), 16163-16173, 2011
Supramolecular control over split‐luciferase complementation
RPG Bosmans, JM Briels, LG Milroy, TFA de Greef, M Merkx, L Brunsveld
Angewandte Chemie International Edition 55 (31), 8899-8903, 2016
Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives
LG Milroy, G Zinzalla, G Prencipe, P Michel, SV Ley, M Gunaratnam, ...
Angewandte Chemie-International Edition 46 (14), 2493-2496, 2007
Carborane–β-cyclodextrin complexes as a supramolecular connector for bioactive surfaces
P Neirynck, J Schimer, P Jonkheijm, LG Milroy, P Cigler, L Brunsveld
Journal of materials chemistry B 3 (4), 539-545, 2015
Structural interface between LRRK2 and 14-3-3 protein
LM Stevers, RMJM de Vries, RG Doveston, LG Milroy, L Brunsveld, ...
Biochemical Journal 474 (7), 1273-1287, 2017
Characterization of coding/noncoding variants for SHROOM3 in patients with CKD
JW Prokop, NC Yeo, C Ottmann, SB Chhetri, KL Florus, EJ Ross, ...
Journal of the American Society of Nephrology 29 (5), 1525-1535, 2018
Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions
E Sijbesma, E Visser, K Plitzko, P Thiel, LG Milroy, M Kaiser, L Brunsveld, ...
Nature communications 11 (1), 3954, 2020
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