| Modulators of protein–protein interactions LG Milroy, TN Grossmann, S Hennig, L Brunsveld, C Ottmann Chemical reviews 114 (9), 4695-4748, 2014 | 495 | 2014 |
| Metal‐free photocatalytic aerobic oxidation of thiols to disulfides in batch and continuous‐flow A Talla, B Driessen, NJW Straathof, LG Milroy, L Brunsveld, V Hessel, ... Advanced Synthesis & Catalysis 357 (10), 2180-2186, 2015 | 203 | 2015 |
| Supramolecular chemistry targeting proteins S van Dun, C Ottmann, LG Milroy, L Brunsveld Journal of the American Chemical Society 139 (40), 13960-13968, 2017 | 196 | 2017 |
| Stabilization of protein-protein interactions in drug discovery SA Andrei, E Sijbesma, M Hann, J Davis, G O’Mahony, MWD Perry, ... Expert opinion on drug discovery 12 (9), 925-940, 2017 | 156 | 2017 |
| Synthesis and structure− activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin R Tannert, LG Milroy, B Ellinger, TS Hu, HD Arndt, H Waldmann Journal of the American Chemical Society 132 (9), 3063-3077, 2010 | 127 | 2010 |
| Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR LM Stevers, CV Lam, SFR Leysen, FA Meijer, DS van Scheppingen, ... Proceedings of the National Academy of Sciences 113 (9), E1152-E1161, 2016 | 126 | 2016 |
| Batch and Flow Synthesis of Disulfides by Visible‐Light‐Induced TiO2 Photocatalysis C Bottecchia, N Erdmann, PMA Tijssen, LG Milroy, L Brunsveld, V Hessel, ... ChemSusChem 9 (14), 1781-1785, 2016 | 103 | 2016 |
| Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives G Zinzalla, LG Milroy, SV Ley Organic & Biomolecular Chemistry 4 (10), 1977-2002, 2006 | 97 | 2006 |
| Stabilization and inhibition of protein–protein interactions: The 14-3-3 case study LG Milroy, L Brunsveld, C Ottmann ACS chemical biology 8 (1), 27-35, 2013 | 93 | 2013 |
| A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit [8] uril and Dimeric Adapter Protein 14‐3‐3 PJ de Vink, JM Briels, T Schrader, LG Milroy, L Brunsveld, C Ottmann Angewandte Chemie 129 (31), 9126-9130, 2017 | 89 | 2017 |
| Supramolecular control of cell adhesion via ferrocene–cucurbit [7] uril host–guest binding on gold surfaces P Neirynck, J Brinkmann, Q An, DWJ van der Schaft, LG Milroy, ... Chemical communications 49 (35), 3679-3681, 2013 | 85 | 2013 |
| Stabilizer‐Guided Inhibition of Protein–Protein Interactions LG Milroy, M Bartel, MA Henen, S Leysen, JMC Adriaans, L Brunsveld, ... Angewandte Chemie International Edition 54 (52), 15720-15724, 2015 | 72 | 2015 |
| Selective chemical imaging of static actin in live cells LG Milroy, S Rizzo, A Calderon, B Ellinger, S Erdmann, J Mondry, ... Journal of the American Chemical Society 134 (20), 8480-8486, 2012 | 68 | 2012 |
| Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins X Qi, F Loiseau, WL Chan, Y Yan, Z Wei, LG Milroy, RM Myers, SV Ley, ... Journal of Biological Chemistry 286 (18), 16163-16173, 2011 | 62 | 2011 |
| Supramolecular control over split‐luciferase complementation RPG Bosmans, JM Briels, LG Milroy, TFA de Greef, M Merkx, L Brunsveld Angewandte Chemie International Edition 55 (31), 8899-8903, 2016 | 60 | 2016 |
| Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives LG Milroy, G Zinzalla, G Prencipe, P Michel, SV Ley, M Gunaratnam, ... Angewandte Chemie-International Edition 46 (14), 2493-2496, 2007 | 60 | 2007 |
| Structural interface between LRRK2 and 14-3-3 protein LM Stevers, RMJM de Vries, RG Doveston, LG Milroy, L Brunsveld, ... Biochemical Journal 474 (7), 1273-1287, 2017 | 55 | 2017 |
| Carborane–β-cyclodextrin complexes as a supramolecular connector for bioactive surfaces P Neirynck, J Schimer, P Jonkheijm, LG Milroy, P Cigler, L Brunsveld Journal of Materials Chemistry B 3 (4), 539-545, 2015 | 54 | 2015 |
| Characterization of coding/noncoding variants for SHROOM3 in patients with CKD JW Prokop, NC Yeo, C Ottmann, SB Chhetri, KL Florus, EJ Ross, ... Journal of the American Society of Nephrology 29 (5), 1525-1535, 2018 | 50 | 2018 |
| Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions E Sijbesma, E Visser, K Plitzko, P Thiel, LG Milroy, M Kaiser, L Brunsveld, ... Nature communications 11 (1), 3954, 2020 | 48 | 2020 |
Luc BrunsveldHoogleraar Chemische Biologie, TU EindhovenVerified email at tue.nl
