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Darren Monckton
Darren Monckton
Verified email at glasgow.ac.uk
Title
Cited by
Cited by
Year
Complex gene conversion events in germline mutation at human minisatellites
AJ Jeffreys, K Tamaki, A MacLeod, DG Monckton, DL Neil, JAL Armour
Nature genetics 6 (2), 136-145, 1994
6401994
Minisatellite repeat coding as a digital approach to DNA typing
AJ Jeffreys, A MacLeod, K Tamaki, DL Neil, DG Monckton
Nature 354 (6350), 204-209, 1991
5601991
Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses
DG Monckton, LJC Wong, T Ashizawa, CT Caskey
Human Molecular Genetics 4 (1), 1-8, 1995
3711995
Somatic heterogeneity of the CTG repeat in myotonic dystrophy is age and size dependent.
LJ Wong, T Ashizawa, DG Monckton, CT Caskey, CS Richards
American journal of human genetics 56 (1), 114, 1995
2821995
Myotonic dystrophy: an unstable CTG repeat in a protein kinase gene
L Timchenko, DG Monckton, CT Caskey
Seminars in cell biology 6 (1), 13-19, 1995
2811995
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset
JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ...
Cell 178 (4), 887-900. e14, 2019
2682019
Pms2 is a genetic enhancer of trinucleotide CAG·CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion
M Gomes-Pereira, MT Fortune, L Ingram, JP McAbney, DG Monckton
Human molecular genetics 13 (16), 1815-1825, 2004
2142004
Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients
L Martorell, DG Monckton, J Gamez, KJ Johnson, I Gich, AL de Munain, ...
Human molecular genetics 7 (2), 307-312, 1998
1981998
Somatic instability of the expanded CTG triplet repeat in myotonic dystrophy type 1 is a heritable quantitative trait and modifier of disease severity
F Morales, JM Couto, CF Higham, G Hogg, P Cuenca, C Braida, ...
Human molecular genetics 21 (16), 3558-3567, 2012
1912012
Variant CCG and GGC repeats within the CTG expansion dramatically modify mutational dynamics and likely contribute toward unusual symptoms in some myotonic dystrophy type 1 …
C Braida, RKA Stefanatos, B Adam, N Mahajan, HJM Smeets, F Niel, ...
Human molecular genetics 19 (8), 1399-1412, 2010
1882010
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
MT Fortune, C Vassilopoulos, MI Coolbaugh, MJ Siciliano, DG Monckton
Human Molecular Genetics 9 (3), 439-445, 2000
1662000
Consensus-based care recommendations for adults with myotonic dystrophy type 1
T Ashizawa, C Gagnon, WJ Groh, L Gutmann, NE Johnson, G Meola, ...
Neurology: Clinical Practice 8 (6), 507-520, 2018
1632018
MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice
S Tomé, K Manley, JP Simard, GW Clark, MM Slean, M Swami, ...
PLoS genetics 9 (2), e1003280, 2013
1622013
Cis-acting modifiers of expanded CAG/CTG triplet repeat expandability: associations with flanking GC content and proximity to CpG islands
GJR Brock, NH Anderson, DG Monckton
Human Molecular Genetics 8 (6), 1061-1067, 1999
1611999
Hypermutable myotonic dystrophy CTG repeats in transgenic mice
DG Monckton, MI Coolbaugh, KT Ashizawa, MJ Siciliano, CT Caskey
Nature genetics 15 (2), 193-196, 1997
1571997
New nomenclature and DNA testing guidelines for myotonic dystrophy type 1 (DM1)
International Myotonic Dystrophy Consortium (IDMC)
Neurology 54 (6), 1218-1221, 2000
1482000
Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism
DG Monckton, R Neumann, T Guram, N Fretwell, K Tamaki, A MacLeod, ...
Nature genetics 8 (2), 162-170, 1994
1421994
MSH3 modifies somatic instability and disease severity in Huntington’s and myotonic dystrophy type 1
M Flower, V Lomeikaite, M Ciosi, S Cumming, F Morales, K Lo, ...
Brain 142 (7), 1876-1886, 2019
1402019
CRISPR/Cas9-induced (CTG⋅ CAG) n repeat instability in the myotonic dystrophy type 1 locus: implications for therapeutic genome editing
EL Van Agtmaal, LM André, M Willemse, SA Cumming, ID Van Kessel, ...
Molecular therapy 25 (1), 24-43, 2017
1382017
A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes
M Ciosi, A Maxwell, SA Cumming, DJH Moss, AM Alshammari, MD Flower, ...
EBioMedicine 48, 568-580, 2019
1322019
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