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Christian Schlein
Christian Schlein
MD, PhD. Principal investigator at University Medical Center Hamburg Eppendorf
Verified email at uke.de
Title
Cited by
Cited by
Year
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ...
Nature communications 6 (1), 6356, 2015
4752015
The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue
MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ...
Nature medicine 23 (5), 631-637, 2017
3722017
FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues
C Schlein, S Talukdar, M Heine, AW Fischer, LM Krott, SK Nilsson, ...
Cell metabolism 23 (3), 441-453, 2016
2552016
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis
A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ...
Nature medicine 23 (7), 839-849, 2017
2532017
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
Y Chen, JJ Buyel, MJW Hanssen, F Siegel, R Pan, J Naumann, M Schell, ...
Nature communications 7 (1), 11420, 2016
1672016
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ...
Nature medicine 24 (3), 292-303, 2018
1652018
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
A Bartelt, C John, N Schaltenberg, JFP Berbée, A Worthmann, ...
Nature communications 8 (1), 15010, 2017
1492017
Lipolysis triggers a systemic insulin response essential for efficient energy replenishment of activated brown adipose tissue in mice
M Heine, AW Fischer, C Schlein, C Jung, LG Straub, K Gottschling, ...
Cell metabolism 28 (4), 644-655. e4, 2018
1442018
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
B Niemann, S Haufs-Brusberg, L Puetz, M Feickert, MY Jaeckstein, ...
Nature 609 (7926), 361-368, 2022
652022
Intact innervation is essential for diet-induced recruitment of brown adipose tissue
AW Fischer, C Schlein, B Cannon, J Heeren, J Nedergaard
American Journal of Physiology-Endocrinology and Metabolism 316 (3), E487-E503, 2019
652019
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
AW Fischer, MY Jaeckstein, K Gottschling, M Heine, F Sass, N Mangels, ...
Cell metabolism 33 (3), 547-564. e7, 2021
472021
Endogenous fatty acid synthesis drives brown adipose tissue involution
C Schlein, AW Fischer, F Sass, A Worthmann, K Tödter, MY Jaeckstein, ...
Cell reports 34 (2), 2021
422021
Homozygosity for a partial deletion of apoprotein AV signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
K Albers, C Schlein, K Wenner, P Lohse, A Bartelt, J Heeren, R Santer, ...
Atherosclerosis 233 (1), 97-103, 2014
332014
Course of HEV viremia and anti-HEV IgM/IgG response in asymptomatic blood donors
C Kraef, C Schlein, J Hiller, D Westhölter, U Denzer, T Horvatits, S Peine, ...
Journal of Clinical Virology 105, 26-30, 2018
272018
FoxO transcription factors are required for hepatic HDL cholesterol clearance
SX Lee, M Heine, C Schlein, R Ramakrishnan, J Liu, G Belnavis, I Haimi, ...
The Journal of clinical investigation 128 (4), 1615-1626, 2018
262018
Genetic dissection of tissue-specific apolipoprotein E function for hypercholesterolemia and diet-induced obesity
T Wagner, A Bartelt, C Schlein, J Heeren
PloS one 10 (12), e0145102, 2015
232015
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
F Sass, C Schlein, MY Jaeckstein, P Pertzborn, M Schweizer, T Schinke, ...
Molecular Metabolism 47, 101173, 2021
192021
Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice
AW Fischer, J Behrens, F Sass, C Schlein, M Heine, P Pertzborn, ...
Journal of Lipid Research 61 (11), 1377-1389, 2020
152020
Thermoneutrality-induced macrophage accumulation in brown adipose tissue does not impair the tissue’s competence for cold-induced thermogenic recruitment
AW Fischer, JMA De Jong, F Sass, C Schlein, J Heeren, N Petrovic
Frontiers in endocrinology 11, 568682, 2020
152020
PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles
AW Fischer, K Albers, C Schlein, F Sass, LM Krott, H Schmale, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019
142019
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