Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and … R Coronel, S Casini, TT Koopmann, FJG Wilms-Schopman, AO Verkerk, ... Circulation 112 (18), 2769-2777, 2005 | 542 | 2005 |
Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem? CC Veerman, G Kosmidis, CL Mummery, S Casini, AO Verkerk, M Bellin Stem cells and development 24 (9), 1035-1052, 2015 | 315 | 2015 |
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease RP Davis, S Casini, CW van den Berg, M Hoekstra, CA Remme, ... Circulation 125 (25), 3079-3091, 2012 | 313 | 2012 |
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long‐QT syndrome M Bellin, S Casini, RP Davis, C D'aniello, J Haas, D Ward‐van Oostwaard, ... The EMBO journal 32 (24), 3161-3175, 2013 | 271 | 2013 |
Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development RP Davis, CW van den Berg, S Casini, SR Braam, CL Mummery Trends in molecular medicine 17 (9), 475-484, 2011 | 166 | 2011 |
Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials AO Verkerk, ACG van Ginneken, G Berecki, HM den Ruijter, ... Cardiovascular research 70 (3), 509-520, 2006 | 125 | 2006 |
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network DJ Anderson, DI Kaplan, KM Bell, K Koutsis, JM Haynes, RJ Mills, ... Nature communications 9 (1), 1373, 2018 | 117 | 2018 |
Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes S Casini, AO Verkerk, MMGJ van Borren, ACG van Ginneken, ... Cardiovascular research 81 (1), 72-81, 2009 | 94 | 2009 |
Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes SR Braam, L Tertoolen, S Casini, E Matsa, HR Lu, A Teisman, R Passier, ... Stem cell research 10 (1), 48-56, 2013 | 90 | 2013 |
Tubulin polymerization modifies cardiac sodium channel expression and gating S Casini, HL Tan, I Demirayak, CA Remme, AS Amin, BP Scicluna, ... Cardiovascular research 85 (4), 691-700, 2010 | 88 | 2010 |
Human iPSC-derived cardiomyocytes for investigation of disease mechanisms and therapeutic strategies in inherited arrhythmia syndromes: strengths and limitations S Casini, AO Verkerk, CA Remme Cardiovascular drugs and therapy 31 (3), 325-344, 2017 | 87 | 2017 |
Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation K Scherschel, K Hedenus, C Jungen, MD Lemoine, N Rübsamen, ... Science translational medicine 11 (493), eaav7770, 2019 | 76 | 2019 |
PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function MJ Birket, S Casini, G Kosmidis, DA Elliott, AA Gerencser, A Baartscheer, ... Stem Cell Reports 1 (6), 560-574, 2013 | 75 | 2013 |
Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4–S5 linker in slow inactivation S Casini, HL Tan, ZA Bhuiyan, CR Bezzina, P Barnett, E Cerbai, A Mugelli, ... Cardiovascular research 76 (3), 418-429, 2007 | 70 | 2007 |
Atrial natriuretic peptide modulates the hyperpolarization-activated current (If) in human atrial myocytes G Lonardo, E Cerbai, S Casini, G Giunti, M Bonacchi, F Battaglia, ... Cardiovascular research 63 (3), 528-536, 2004 | 54 | 2004 |
Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/− and human SCN5A-1795insD+/− iPSC-derived … V Portero, S Casini, M Hoekstra, AO Verkerk, I Mengarelli, L Belardinelli, ... Cardiovascular research 113 (7), 829-838, 2017 | 50 | 2017 |
Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure G Kosmidis, M Bellin, MC Ribeiro, B van Meer, D Ward-van Oostwaard, ... Biochemical and biophysical research communications 467 (4), 998-1005, 2015 | 39 | 2015 |
Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes Carrying … G Kosmidis, CC Veerman, S Casini, AO Verkerk, S van de Pas, M Bellin, ... Circulation: Arrhythmia and Electrophysiology 9 (11), e004227, 2016 | 38 | 2016 |
KV4.3 Expression Modulates NaV1.5 Sodium Current V Portero, R Wilders, S Casini, F Charpentier, AO Verkerk, CA Remme Frontiers in physiology 9, 178, 2018 | 37 | 2018 |
Chronically elevated branched chain amino acid levels are pro-arrhythmic V Portero, T Nicol, S Podliesna, GA Marchal, A Baartscheer, S Casini, ... Cardiovascular research 118 (7), 1742-1757, 2022 | 31 | 2022 |