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Matthew M Heberling
Matthew M Heberling
Cofounder at Peptone. Rationalizing failure for better medicines.
Geverifieerd e-mailadres voor peptone.io - Homepage
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Priming ammonia lyases and aminomutases for industrial and therapeutic applications
MM Heberling, B Wu, S Bartsch, DB Janssen
Current Opinion in Chemical Biology 17 (2), 250-260, 2013
1092013
Aminomutases: mechanistic diversity, biotechnological applications and future perspectives
B Wu, W Szymański, MM Heberling, BL Feringa, DB Janssen
Trends in biotechnology 29 (7), 352-362, 2011
732011
Mechanism-inspired engineering of phenylalanine aminomutase for enhanced β-regioselective asymmetric amination of cinnamates.
B Wu, W Szymański, GG Wybenga, MM Heberling, S Bartsch, ...
Angewandte Chemie (International ed. in English) 51 (2), 482-486, 2011
682011
Redesign of a phenylalanine aminomutase into a phenylalanine ammonia lyase
S Bartsch, GG Wybenga, M Jansen, MM Heberling, B Wu, BW Dijkstra, ...
ChemCatChem 5 (7), 1797-1802, 2013
402013
DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
A Batyuk, Y Wu, A Honegger, MM Heberling, A Plückthun
Journal of Molecular Biology 428 (8), 1574-1588, 2016
352016
Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase
MM Heberling, MF Masman, S Bartsch, GG Wybenga, BW Dijkstra, ...
ACS chemical biology 10 (4), 989-997, 2015
332015
ADOPT: intrinsic protein disorder prediction through deep bidirectional transformers
I Redl, C Fisicaro, O Dutton, F Hoffmann, L Henderson, BMJ Owens, ...
NAR Genomics and Bioinformatics 5 (2), lqad041, 2023
102023
Metabolism of β-valine via a CoA-dependent ammonia lyase pathway
M Otzen, CG Crismaru, CP Postema, HJ Wijma, MM Heberling, ...
Applied microbiology and biotechnology 99, 8987-8998, 2015
42015
Structural Propensity Database of Proteins
K Tamiola, MM Heberling, J Domanski
bioRxiv.org 144840, 2017
12017
Improving Stability of Tumor Suppressor Protein, p53
M Heberling
The Ohio State University, 2007
12007
Genomics-based discovery and engineering of biocatalysts for conversion of amines
MM Heberling
2017
From Aminomutases to Ammonia Lyases: A Protein Engineering Study
MF Masman, MM Heberling, DB Janssen
Biophysical Journal 106 (2), 655a, 2014
2014
Computation-supported enzyme engineering for preparative biocatalysis
DB Janssen, R Floor, MM Heberling, S Bartsch, HJ Wijma
FEBS JOURNAL 280, 591-592, 2013
2013
PAM/PAL review
MM Heberling, B Wu, S Bartsch, DB Janssen
Current Opinion in Chemical Biology 17 (250), 2013
2013
Engineering promiscuous lyases for enantioselective biocatalysis
DB Janssen, B Wu, S Bartsch, MM Heberling, W Szymanski, CG Crismaru
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012
2012
Structural propensity database of
K Tamiola, MM Heberling, J Domanski
Supplementary Information for
A Batyuk, Y Wu, A Honegger, MM Heberling, A Plückthun
Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced b-Regioselective Asymmetric Amination of Cinnamates
B Wu, W Szymanski, GG Wybenga, MM Heberling, S Bartsch, ...
Full wwPDB X-ray Structure Validation Report i○
Y Hai, JE Edwards, MC Van Zandt, KF Hoffmann, DW Christianson
From Aminomutases to Ammonia Lyases
MF Masman, MM Heberling, D Janssen
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Artikelen 1–20