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David C. de Leeuw
David C. de Leeuw
MD. PhD. Internist-hematologist
Geverifieerd e-mailadres voor vumc.nl
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Jaar
Attenuation of microRNA-126 Expression That Drives CD34+38 Stem/Progenitor Cells in Acute Myeloid Leukemia Leads to Tumor Eradication
DC De Leeuw, F Denkers, MC Olthof, AP Rutten, W Pouwels, ...
Cancer research 74 (7), 2094-2105, 2014
1122014
A threshold of 10% for myeloperoxidase by flow cytometry is valid to classify acute leukemia of ambiguous and myeloid origin
W van den Ancker, TM Westers, DC de Leeuw, YFCM van der Veeken, ...
Cytometry Part B: Clinical Cytometry 84 (2), 114-118, 2013
612013
MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia
DC de Leeuw, W van den Ancker, F Denkers, RX de Menezes, ...
Clinical Cancer Research 19 (8), 2187-2196, 2013
582013
IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival
HJMP Verhagen, DC De Leeuw, MGM Roemer, F Denkers, W Pouwels, ...
Cell death & disease 5 (6), e1300-e1300, 2014
352014
Targeting acute myeloid leukemia with venetoclax; biomarkers for sensitivity and rationale for venetoclax-based combination therapies
MS Griffioen, DC de Leeuw, JJWM Janssen, L Smit
Cancers 14 (14), 3456, 2022
242022
MicroRNA-551b is highly expressed in hematopoietic stem cells and a biomarker for relapse and poor prognosis in acute myeloid leukemia
DC De Leeuw, H Verhagen, F Denkers, FG Kavelaars, PJM Valk, ...
Leukemia 30 (3), 742-746, 2016
212016
Older patients with acute myeloid leukemia deserve individualized treatment
DC de Leeuw, GJ Ossenkoppele, JJWM Janssen
Current oncology reports 24 (11), 1387-1400, 2022
192022
IGFBP7 induces differentiation and loss of survival of human acute myeloid leukemia stem cells without affecting normal hematopoiesis
HJMP Verhagen, N van Gils, T Martiañez, A van Rhenen, A Rutten, ...
Cell reports 25 (11), 3021-3035. e5, 2018
192018
Specific depletion of leukemic stem cells: Can microRNAs make the difference?
T Martiáñez Canales, DC De Leeuw, E Vermue, GJ Ossenkoppele, L Smit
Cancers 9 (7), 74, 2017
102017
Optimizing antiviral dosing for HSV and CMV treatment in immunocompromised patients
DW Huntjens, JA Dijkstra, LN Verwiel, M Slijkhuis, P Elbers, MRA Welkers, ...
Pharmaceutics 15 (1), 163, 2023
82023
Case report: Candida krusei spondylitis in an immunocompromised patient
AJC Overgaauw, DC de Leeuw, SP Stoof, K van Dijk, JCJ Bot, ...
BMC Infectious Diseases 20 (1), 739, 2020
82020
Prospective validation of the prognostic relevance of CD34+CD38 AML stem cell frequency in the HOVON-SAKK132 trial
LL Ngai, D Hanekamp, F Janssen, J Carbaat-Ham, MAMA Hofland, ...
Blood, The Journal of the American Society of Hematology 141 (21), 2657-2661, 2023
72023
An open-label, first-in-human, dose-escalation study of SAR443579 administered as single agent by intravenous infusion in patients with relapsed or refractory acute myeloid …
AS Stein, A Bajel, S Fleming, M Jongen-Lavrencic, S Garciaz, A Maiti, ...
Blood 140 (Supplement 1), 7476-7477, 2022
62022
High-dose melphalan in 1 day versus over 2 days followed by autologous stem cell transplantation as consolidation treatment in patients with multiple myeloma
M Aydin, MW Tang, M Wondergem, DC de Leeuw, JJ Wegman, ...
Blood 138, 3944, 2021
52021
Challenging diagnosis in a patient with clear lymphoid immunohistochemical features and myeloid morphology: Mixed phenotype acute leukemia with erythrophagocytosis
DC de Leeuw, W van den Ancker, TM Westers, AH Loonen, SL Bhola, ...
Leukemia research 35 (5), 693-696, 2011
42011
Covalent menin inhibitor Bmf-219 in patients with relapsed or refractory (R/R) acute leukemia (AL): preliminary phase 1 data from the Covalent-101 study
J Lancet, F Ravandi, P Montesinos, JC Barrientos, T Badar, A Alegre, ...
Blood 142, 2916, 2023
32023
Impact of hemodilution on flow cytometry based measurable residual disease assessment in acute myeloid leukemia
JM Tettero, ME Heidinga, TR Mocking, G Fransen, A Kelder, WJ Scholten, ...
Leukemia, 1-10, 2024
22024
First-in-Human Study of the CD123 NK Cell Engager SAR443579 in Relapsed or Refractory Acute Myeloid Leukemia, B-Cell Acute Lymphoblastic Leukemia or High Risk-Myelodysplasia …
A Bajel, S Garciaz, P Desai, GA Huls, A Maiti, M Jongen-Lavrencic, ...
Blood 142, 3474, 2023
22023
EP0042, a dual FLT3 and Aurora kinase inhibitor: preliminary results of an ongoing phase I/IIa first in human study in patients with relapsed/refractory acute myeloid leukemia
D Taussig, J O'Nions, M Jongen-Lavrencic, JJ Janssen, DC de Leeuw, ...
Blood 140 (Supplement 1), 6222-6223, 2022
22022
Transient seizure-induced sodium increase camouflaging a symptomatic hyponatremia
DC de Leeuw, AJ Kooter
BMJ Case Reports CP 13 (1), e229328, 2020
22020
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Artikelen 1–20