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xiangkun han
xiangkun han
Research fellow, Harvard Medical School
Verified email at hms.harvard.edu
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Year
Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases
Y Sun, Y Ren, Z Fang, C Li, R Fang, B Gao, X Han, W Tian, W Pao, ...
Journal of clinical oncology 28 (30), 4616, 2010
3822010
VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex
W Zhang, Y Gao, P Li, Z Shi, T Guo, F Li, X Han, Y Feng, C Zheng, ...
Cell research 24 (3), 331-343, 2014
3122014
Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers
C Li, R Fang, Y Sun, X Han, F Li, B Gao, AJ Iafrate, XY Liu, W Pao, ...
PloS one 6 (11), e28204, 2011
2662011
LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling
Y Gao, Q Xiao, HM Ma, L Li, J Liu, Y Feng, Z Fang, J Wu, X Han, J Zhang, ...
Proceedings of the National Academy of Sciences 107 (44), 18892-18897, 2010
2092010
Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma
X Han, F Li, Z Fang, Y Gao, F Li, R Fang, S Yao, Y Sun, L Li, W Zhang, ...
Nature communications 5 (1), 3261, 2014
1572014
LKB1 inactivation elicits a redox imbalance to modulate non-small cell lung cancer plasticity and therapeutic response
F Li, X Han, F Li, R Wang, H Wang, Y Gao, X Wang, Z Fang, W Zhang, ...
Cancer cell 27 (5), 698-711, 2015
1402015
Spectrum of LKB1, EGFR, and KRAS mutations in chinese lung adenocarcinomas
B Gao, Y Sun, J Zhang, Y Ren, R Fang, X Han, L Shen, X Liu, W Pao, ...
Journal of thoracic oncology 5 (8), 1130-1135, 2010
1182010
YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression
Y Gao, W Zhang, X Han, F Li, X Wang, R Wang, Z Fang, X Tong, S Yao, ...
Nature communications 5 (1), 4629, 2014
1142014
Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains
C Li, Y Sun, R Fang, X Han, X Luo, R Wang, Y Pan, H Hu, Y Zhang, ...
Journal of Thoracic Oncology 7 (1), 85-89, 2012
1082012
Identification of RET gene fusion by exon array analyses in “pan-negative” lung cancer from never smokers
F Li, Y Feng, R Fang, Z Fang, J Xia, X Han, XY Liu, H Chen, H Liu, H Ji
Cell research 22 (5), 928-931, 2012
912012
YAP Promotes Malignant Progression of Lkb1-Deficient Lung Adenocarcinoma through Downstream Regulation of Survivin
W Zhang, Y Gao, F Li, X Tong, Y Ren, X Han, S Yao, F Long, Z Yang, ...
Cancer research 75 (21), 4450-4457, 2015
872015
Branched-chain amino acid metabolic reprogramming orchestrates drug resistance to EGFR tyrosine kinase inhibitors
Y Wang, J Zhang, S Ren, D Sun, HY Huang, H Wang, Y Jin, F Li, C Zheng, ...
Cell reports 28 (2), 512-525. e6, 2019
682019
Seasonal effects on apoptosis and proliferation of germ cells in the testes of the Chinese soft-shelled turtle, Pelodiscus sinensis
L Zhang, XK Han, YY Qi, Y Liu, QS Chen
Theriogenology 69 (9), 1148-1158, 2008
592008
Evidence, mechanism, and clinical relevance of the transdifferentiation from lung adenocarcinoma to squamous cell carcinoma
S Hou, S Zhou, Z Qin, L Yang, X Han, S Yao, H Ji
The American journal of pathology 187 (5), 954-962, 2017
562017
Spermiogenesis in Soft‐Shelled Turtle, Pelodiscus sinensis
L Zhang, XK Han, MY Li, HJ Bao, QS Chen
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2007
462007
Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma
F Li, Z Fang, J Zhang, C Li, H Liu, J Xia, H Zhu, C Guo, Z Qin, F Li, X Han, ...
Cell research 26 (10), 1149-1164, 2016
352016
Evolution from genetics to phenotype: reinterpretation of NSCLC plasticity, heterogeneity, and drug resistance
Y Xue, S Hou, H Ji, X Han
Protein & cell 8 (3), 178-190, 2017
322017
Seasonal changes of sperm storage and correlative structures in male and female soft-shelled turtles, Trionyx sinensis
H Xiangkun, Z Li, L Meiying, B Huijun, H Nainan, C Qiusheng
Animal reproduction science 108 (3-4), 435-445, 2008
312008
Comprehensive analysis of epidermal growth factor receptor gene status in lung adenocarcinoma
C Li, Y Sun, Z Fang, X Han, R Fang, Y Zhang, Y Pan, W Zhang, Y Ren, ...
Journal of Thoracic Oncology 6 (6), 1016-1021, 2011
302011
Integrative genomic analysis reveals a high frequency of LKB1 genetic alteration in Chinese lung adenocarcinomas
R Fang, C Zheng, Y Sun, X Han, B Gao, C Li, H Liu, KK Wong, XY Liu, ...
Journal of Thoracic Oncology 9 (2), 254-258, 2014
282014
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