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Polina Prokofeva
Polina Prokofeva
Chair of Proteomics and Bioanalytics, Technical University of Munich
Geverifieerd e-mailadres voor tum.de - Homepage
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Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target
S Lechner, MIP Malgapo, C Grätz, RR Steimbach, A Baron, P Rüther, ...
Nature chemical biology 18 (8), 812-820, 2022
462022
Decrypting drug actions and protein modifications by dose-and time-resolved proteomics
J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ...
Science 380 (6640), 93-101, 2023
242023
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
WT Lo, H Belabed, M Kücükdisli, J Metag, Y Roske, P Prokofeva, ...
Nature chemical biology 19 (1), 18-27, 2023
122023
Merits of Diazirine Photo-Immobilization for Target Profiling of Natural Products and Cofactors
P Prokofeva, S Höfer, M Hornisch, M Abele, B Kuster, G Médard
ACS Chemical Biology 17 (11), 3100-3109, 2022
32022
Target deconvolution of HDAC pharmacopoeia highlights MBLAC2 as common off-target
S Lechner, M Malgapo, C Grätz, A Baron, PL Rüther, S Nadal, C Stumpf, ...
12021
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition
M Kücükdisli, H Bel-Abed, D Cirillo, WT Lo, NL Efrém, A Horatscheck, ...
Journal of Medicinal Chemistry 66 (20), 14278-14302, 2023
2023
Targeting cancer with small molecule pan-KRAS degraders
J Popow, W Farnaby, A Gollner, C Kofink, G Fischer, M Wurm, D Zollman, ...
bioRxiv, 2023.10. 24.563163, 2023
2023
Pushing the boundaries of affinity-based target deconvolution: Promiscuous immobilization of nature-made molecules and proteome-wide medicinal chemistry
P Prokofeva
Technische Universität München, 2023
2023
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Artikelen 1–8