| Derivation of pluripotent epiblast stem cells from mammalian embryos IGM Brons, LE Smithers, MWB Trotter, P Rugg-Gunn, B Sun, ... Nature 448 (7150), 191-195, 2007 | 1630 | 2007 |
| Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells L Vallier, M Alexander, RA Pedersen Journal of cell science 118 (19), 4495-4509, 2005 | 1075 | 2005 |
| Targeted gene correction of α 1-antitrypsin deficiency in induced pluripotent stem cells K Yusa, ST Rashid, H Strick-Marchand, I Varela, PQ Liu, DE Paschon, ... Nature 478 (7369), 391-394, 2011 | 656 | 2011 |
| Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells ST Rashid, S Corbineau, N Hannan, SJ Marciniak, E Miranda, ... The Journal of clinical investigation 120 (9), 3127-3136, 2010 | 588 | 2010 |
| Senescence impairs successful reprogramming to pluripotent stem cells A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ... Genes & development 23 (18), 2134-2139, 2009 | 583 | 2009 |
| Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development T Touboul, NRF Hannan, S Corbineau, A Martinez, C Martinet, ... Hepatology 51 (5), 1754-1765, 2010 | 482 | 2010 |
| The cell-cycle state of stem cells determines cell fate propensity S Pauklin, L Vallier Cell 155 (1), 135-147, 2013 | 427 | 2013 |
| Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway L Vallier, D Reynolds, RA Pedersen Developmental biology 275 (2), 403-421, 2004 | 420 | 2004 |
| Activin/Nodal signalling maintains pluripotency by controlling Nanog expression L Vallier, S Mendjan, S Brown, Z Chng, A Teo, LE Smithers, MWB Trotter, ... Development 136 (8), 1339-1349, 2009 | 412 | 2009 |
| Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm JR Smith, L Vallier, G Lupo, M Alexander, WA Harris, RA Pedersen Developmental biology 313 (1), 107-117, 2008 | 310 | 2008 |
| Pluripotency factors regulate definitive endoderm specification through eomesodermin AKK Teo, SJ Arnold, MWB Trotter, S Brown, LT Ang, Z Chng, ... Genes & development 25 (3), 238-250, 2011 | 288 | 2011 |
| SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ... Nature medicine 26 (5), 681-687, 2020 | 277 | 2020 |
| Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways L Vallier, T Touboul, Z Chng, M Brimpari, N Hannan, E Millan, ... PloS one 4 (6), e6082, 2009 | 261 | 2009 |
| Common genetic variation drives molecular heterogeneity in human iPSCs H Kilpinen, A Goncalves, A Leha, V Afzal, K Alasoo, S Ashford, S Bala, ... Nature 546 (7658), 370-375, 2017 | 238 | 2017 |
| Production of hepatocyte-like cells from human pluripotent stem cells NRF Hannan, CP Segeritz, T Touboul, L Vallier Nature protocols 8 (2), 430-437, 2013 | 231 | 2013 |
| Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury RP Fordham, S Yui, NRF Hannan, C Soendergaard, A Madgwick, ... Cell stem cell 13 (6), 734-744, 2013 | 218 | 2013 |
| Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis MN Weedon, I Cebola, AM Patch, SE Flanagan, E De Franco, R Caswell, ... Nature genetics 46 (1), 61-64, 2014 | 210 | 2014 |
| Genetic background drives transcriptional variation in human induced pluripotent stem cells F Rouhani, N Kumasaka, MC de Brito, A Bradley, L Vallier, D Gaffney PLoS Genet 10 (6), e1004432, 2014 | 205 | 2014 |
| Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes M Baxter, S Withey, S Harrison, CP Segeritz, F Zhang, R Atkinson-Dell, ... Journal of hepatology 62 (3), 581-589, 2015 | 195 | 2015 |
| Genome editing reveals a role for OCT4 in human embryogenesis NME Fogarty, A McCarthy, KE Snijders, BE Powell, N Kubikova, ... Nature 550 (7674), 67-73, 2017 | 185 | 2017 |
Roger PedersenUniversity of CambridgeVerified email at cam.ac.uk
