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Pravinkumar Purushothaman
Pravinkumar Purushothaman
Associate Director, Clinical Science, Astellas Gene Therapies
Geverifieerd e-mailadres voor audentestx.com
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Differential roles of C4 and βC1 in mediating suppression of post-transcriptional gene silencing: Evidence for transactivation by the C2 of Bhendi yellow vein mosaic virus, a …
P Gopal, P Pravin Kumar, B Sinilal, J Jose, A Kasin Yadunandam, R Usha
Virus research 123 (1), 9-18, 2007
1502007
Regulation of viral and cellular gene expression by Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA
CC Rossetto, M Tarrant-Elorza, S Verma, P Purushothaman, GS Pari
Journal of virology 87 (10), 5540-5553, 2013
1432013
Molecular Biology of KSHV Lytic Reactivation
P Purushothaman, T Uppal, S Verma
Viruses 7 (10.3390/v7010116), 116-153, 2015
1352015
Production of siRNA targeted against TYLCV coat protein transcripts leads to silencing of its expression and resistance to the virus
A Zrachya, PP Kumar, U Ramakrishnan, Y Levy, A Loyter, T Arazi, ...
Transgenic research 16, 385-398, 2007
1182007
Bacteriophage application on red meats and poultry: Effects on Salmonella population in final ground products
Y Yeh, P Purushothaman, N Gupta, M Ragnone, SC Verma, AS De Mello
Meat science 127, 30-34, 2017
1032017
KSHV genome replication and maintenance
P Purushothaman, P Dabral, N Gupta, R Sarkar, SC Verma
Frontiers in microbiology 7, 179701, 2016
932016
G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV
A Madireddy, P Purushothaman, CP Loosbroock, ES Robertson, ...
Nucleic acids research 44 (8), 3675-3694, 2016
852016
Use of the MS2 aptamer and coat protein for RNA localization in yeast: a response to “MS2 coat proteins bound to yeast mRNAs block 5′ to 3′ degradation and trap mRNA decay …
G Haimovich, D Zabezhinsky, B Haas, B Slobodin, P Purushothaman, ...
Rna 22 (5), 660-666, 2016
642016
KSHV-mediated angiogenesis in tumor progression
P Purushothaman, T Uppal, R Sarkar, SC Verma
Viruses 8 (7), 198, 2016
562016
Animal biotechnology: models in discovery and translation
AS Verma, A Singh
Academic Press, 2013
522013
Protein–protein interactions and nuclear trafficking of coat protein and βC1 protein associated with Bhendi yellow vein mosaic disease
R Usha, A Zrachya, Y Levy, H Spanov, Y Gafni
Virus Research 122 (1-2), 127-136, 2006
492006
Transcriptome Analysis of KSHV During De Novo Primary Infection of Human B and Endothelial Cells
P Purushothaman, S Thakker, S Verma
Journal of Virology 89 (6), 3093-111, 2014
48*2014
KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation
RC Strahan, M McDowell-Sargent, T Uppal, P Purushothaman, SC Verma
PLoS pathogens 13 (7), e1006482, 2017
402017
Phosphorylation of Kaposi's Sarcoma-Associated Herpesvirus Processivity Factor ORF59 by a Viral Kinase Modulates Its Ability To Associate with RTA and oriLyt
ME McDowell, P Purushothaman, CC Rossetto, GS Pari, SC Verma
Journal of virology 87 (14), 8038-8052, 2013
362013
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen inhibits major histocompatibility complex class II expression by disrupting enhanceosome assembly …
S Thakker, P Purushothaman, N Gupta, S Challa, Q Cai, SC Verma
Journal of virology 89 (10), 5536-5556, 2015
322015
Kaposi's sarcoma-associated herpesvirus-encoded LANA recruits topoisomerase IIβ for latent DNA replication of the terminal repeats
P Purushothaman, ME McDowell, J McGuinness, R Salas, SM Rumjahn, ...
Journal of virology 86 (18), 9983-9994, 2012
312012
Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins
SK Park, F Arslan, V Kanneganti, SJ Barmada, P Purushothaman, ...
Prion 12 (1), 16-22, 2018
302018
Molecular biology of KSHV lytic reactivation. Viruses 7: 116–153
P Purushothaman, T Uppal, SC Verma
232015
Muscle‐directed gene therapy corrects Pompe disease and uncovers species‐specific GAA immunogenicity
M Eggers, CH Vannoy, J Huang, P Purushothaman, J Brassard, C Fonck, ...
EMBO Molecular Medicine 14 (1), e13968, 2022
212022
KSHV lytic proteins K-RTA and K8 bind to cellular and viral chromatin to modulate gene expression
R Kaul, P Purushothaman, T Uppal, SC Verma
PLoS One 14 (4), e0215394, 2019
172019
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Artikelen 1–20