Anh Tuan Nguyen
Anh Tuan Nguyen
Senior Research Fellow, Institute of Molecular and Cell Biology, Singapore
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An inducible krasV12 transgenic zebrafish model for liver tumorigenesis and chemical drug screening
AT Nguyen, A Emelyanov, CHV Koh, JM Spitsbergen, S Parinov, Z Gong
Disease models & mechanisms 5 (1), 63-72, 2012
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model
EA Bard-Chapeau, AT Nguyen, AG Rust, A Sayadi, P Lee, BQ Chua, ...
Nature genetics 46 (1), 24-32, 2014
A high level of liver-specific expression of oncogenic KrasV12 drives robust liver tumorigenesis in transgenic zebrafish
AT Nguyen, A Emelyanov, CHV Koh, JM Spitsbergen, SH Lam, ...
Disease models & mechanisms 4 (6), 801-813, 2011
Organelle specific O-glycosylation drives MMP14 activation, tumor growth, and metastasis
AT Nguyen, J Chia, M Ros, KM Hui, F Saltel, F Bard
Cancer cell 32 (5), 639-653. e6, 2017
Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma
W Zheng, Z Li, AT Nguyen, C Li, A Emelyanov, Z Gong
PloS one 9 (3), e91179, 2014
Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response
A Sayadi, AT Nguyen, FA Bard, EA Bard-Chapeau
Inflammation Research 62 (2), 133-143, 2013
Myc-induced liver tumors in transgenic zebrafish can regress in tp53 null mutation
L Sun, AT Nguyen, JM Spitsbergen, Z Gong
PloS one 10 (1), e0117249, 2015
One step forward: the use of transgenic zebrafish tumor model in drug screens
X Huang, AT Nguyen, Z Li, A Emelyanov, S Parinov, Z Gong
Birth Defects Research Part C: Embryo Today: Reviews 93 (2), 173-181, 2011
The zebrafish model for liver carcinogenesis
Z Gong, CHV Koh, AT Nguyen, H Zhan, Z Li, SH Lam, JM Spitsbergen, ...
Molecular Genetics of Liver Neoplasia, 197-218, 2010
Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
AT Nguyen, V Koh, JM Spitsbergen, Z Gong
Scientific reports 6 (1), 1-10, 2016
ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells
M Ros, AT Nguyen, J Chia, S Le Tran, X Le Guezennec, R McDowall, ...
Nature cell biology 22 (11), 1371-1381, 2020
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