| Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics MAC Depuydt, KHM Prange, L Slenders, T Örd, D Elbersen, A Boltjes, ... Circulation research 127 (11), 1437-1455, 2020 | 334 | 2020 |
| Transcriptional and epigenetic regulation of macrophages in atherosclerosis T Kuznetsova, KHM Prange, CK Glass, MPJ De Winther Nature Reviews Cardiology 17 (4), 216-228, 2020 | 217 | 2020 |
| A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia J Baardman, SGS Verberk, KHM Prange, M van Weeghel, ... Cell reports 25 (8), 2044-2052. e5, 2018 | 160 | 2018 |
| Atherogenic lipoprotein (a) increases vascular glycolysis, thereby facilitating inflammation and leukocyte extravasation JG Schnitzler, RM Hoogeveen, L Ali, KHM Prange, F Waissi, ... Circulation research 126 (10), 1346-1359, 2020 | 110 | 2020 |
| Treatment with statins does not revert trained immunity in patients with familial hypercholesterolemia S Bekkering, LCA Stiekema, SB Moens, SL Verweij, B Novakovic, ... Cell metabolism 30 (1), 1-2, 2019 | 110 | 2019 |
| MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia KHM Prange, A Mandoli, T Kuznetsova, SY Wang, AM Sotoca, ... Oncogene 36 (23), 3346-3356, 2017 | 99 | 2017 |
| CBFB–MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv (16) acute … A Mandoli, AA Singh, P Jansen, ATJ Wierenga, H Riahi, G Franci, ... Leukemia 28 (4), 770, 2014 | 86 | 2014 |
| Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques J Baardman, SGS Verberk, S Van der Velden, MJJ Gijbels, ... Nature communications 11 (1), 6296, 2020 | 83 | 2020 |
| The hematopoietic transcription factors RUNX1 and ERG prevent AML1-ETO oncogene overexpression and onset of the apoptosis program in t (8; 21) AMLs A Mandoli, AA Singh, KHM Prange, E Tijchon, M Oerlemans, R Dirks, ... Cell reports 17 (8), 2087-2100, 2016 | 67 | 2016 |
| Potent lipoprotein (a) lowering following apolipoprotein (a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated … LCA Stiekema, KHM Prange, RM Hoogeveen, SL Verweij, J Kroon, ... European heart journal 41 (24), 2262-2271, 2020 | 64 | 2020 |
| The oncofusion protein FUS–ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t (16; 21) acute myeloid leukemia AM Sotoca, KHM Prange, B Reijnders, A Mandoli, LN Nguyen, ... Oncogene 35 (15), 1965-1976, 2016 | 48 | 2016 |
| Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease M Lacy, C Bürger, A Shami, M Ahmadsei, H Winkels, K Nitz, CM van Tiel, ... Nature communications 12 (1), 3754, 2021 | 45 | 2021 |
| Impact of cholesterol on proinflammatory monocyte production by the bone marrow LCA Stiekema, L Willemsen, Y Kaiser, KHM Prange, NJ Wareham, ... European Heart Journal 42 (42), 4309-4320, 2021 | 39 | 2021 |
| Chromatin-based classification of genetically heterogeneous AMLs into two distinct subtypes with diverse stemness phenotypes G Yi, ATJ Wierenga, F Petraglia, P Narang, EM Janssen-Megens, ... Cell reports 26 (4), 1059-1069. e6, 2019 | 37 | 2019 |
| Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells MAC Depuydt, FH Schaftenaar, KHM Prange, A Boltjes, E Hemme, ... Nature Cardiovascular Research 2 (2), 112-125, 2023 | 34 | 2023 |
| Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis L Slenders, LPL Landsmeer, K Cui, MAC Depuydt, M Verwer, J Mekke, ... European heart journal open 2 (1), oeab043, 2022 | 32 | 2022 |
| DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages I Cobo, TN Tanaka, KC Mangalhara, A Lana, C Yeang, C Han, ... Immunity 55 (8), 1386-1401. e10, 2022 | 28 | 2022 |
| Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells AE Neele, KHM Prange, MA Hoeksema, S Van Der Velden, T Lucas, ... Epigenomics 9 (4), 383-391, 2017 | 25 | 2017 |
| AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis AA Singh, A Mandoli, KHM Prange, M Laakso, JHA Martens Oncotarget 8 (8), 12855, 2017 | 24 | 2017 |
| The genome-wide molecular signature of transcription factors in leukemia KHM Prange, AA Singh, JHA Martens Experimental hematology 42 (8), 637-650, 2014 | 20 | 2014 |
Menno de WintherProfessor of Vascular Immune Cell BiologyVerified email at amsterdamumc.nl
