Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4352 | 2013 |
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3301 | 2009 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2187 | 2019 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2162 | 2011 |
Genome-wide analysis of genetic loci associated with Alzheimer disease S Seshadri, AL Fitzpatrick, MA Ikram, AL DeStefano, V Gudnason, ... Jama 303 (18), 1832-1840, 2010 | 1449 | 2010 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1367 | 2018 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 903 | 2017 |
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia N Cope, D Harold, G Hill, V Moskvina, J Stevenson, P Holmans, MJ Owen, ... The American Journal of Human Genetics 76 (4), 581-591, 2005 | 455 | 2005 |
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ... PloS one 5 (11), e13950, 2010 | 447 | 2010 |
Common polygenic variation enhances risk prediction for Alzheimer’s disease V Escott-Price, R Sims, C Bannister, D Harold, M Vronskaya, E Majounie, ... Brain 138 (12), 3673-3684, 2015 | 423 | 2015 |
Identification of genetic factors that modify clinical onset of Huntington’s disease JM Lee, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto, D Lucente, ... Cell 162 (3), 516-526, 2015 | 410 | 2015 |
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology J Chapuis, F Hansmannel, M Gistelinck, A Mounier, ... Molecular psychiatry 18 (11), 1225-1234, 2013 | 405 | 2013 |
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013 | 381 | 2013 |
European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease; Alzheimer’s Disease Genetic Consortium; Cohorts for Heart and Aging … JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nat Genet 45 (12), 1452-1458, 2013 | 292 | 2013 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 287 | 2016 |
Remapping the Insulin Gene/IDDM2 Locus in Type 1 Diabetes BJ Barratt, F Payne, CE Lowe, R Hermann, BC Healy, D Harold, ... Diabetes 53 (7), 1884-1889, 2004 | 282 | 2004 |
Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis SH Lee, D Harold, DR Nyholt, ME Goddard, KT Zondervan, J Williams, ... Human molecular genetics 22 (4), 832-841, 2013 | 221 | 2013 |
Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia D Harold, S Paracchini, T Scerri, M Dennis, N Cope, G Hill, V Moskvina, ... Molecular psychiatry 11 (12), 1085-1091, 2006 | 214 | 2006 |
Meta-analysis of the association between variants in SORL1 and Alzheimer disease C Reitz, R Cheng, E Rogaeva, JH Lee, S Tokuhiro, F Zou, K Bettens, ... Archives of neurology 68 (1), 99-106, 2011 | 212 | 2011 |
Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus RS Desikan, AJ Schork, Y Wang, A Witoelar, M Sharma, LK McEvoy, ... Molecular psychiatry 20 (12), 1588-1595, 2015 | 183 | 2015 |