| Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis J Huang, X Liu, D Li, Z Shao, H Cao, Y Zhang, E Trompouki, TV Bowman, ... Developmental cell 36 (1), 9-23, 2016 | 224 | 2016 |
| Dissecting super-enhancer hierarchy based on chromatin interactions J Huang, K Li, W Cai, X Liu, Y Zhang, SH Orkin, J Xu, GC Yuan Nature communications 9 (1), 943, 2018 | 211 | 2018 |
| Systematic prediction of pharmacodynamic drug-drug interactions through protein-protein-interaction network J Huang, C Niu, CD Green, L Yang, H Mei, JDJ Han PLoS computational biology 9 (3), e1002998, 2013 | 172 | 2013 |
| Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions J Xu, Z Shao, D Li, H Xie, W Kim, J Huang, JE Taylor, L Pinello, K Glass, ... Molecular cell 57 (2), 304-316, 2015 | 150 | 2015 |
| Predicting chromatin organization using histone marks J Huang, E Marco, L Pinello, GC Yuan Genome biology 16, 1-11, 2015 | 117 | 2015 |
| PKA phosphorylation couples hepatic inositol-requiring enzyme 1α to glucagon signaling in glucose metabolism T Mao, M Shao, Y Qiu, J Huang, Y Zhang, B Song, Q Wang, L Jiang, Y Liu, ... Proceedings of the National Academy of Sciences 108 (38), 15852-15857, 2011 | 105 | 2011 |
| Bcl11a deficiency leads to hematopoietic stem cell defects with an aging-like phenotype S Luc, J Huang, JL McEldoon, E Somuncular, D Li, C Rhodes, S Mamoor, ... Cell reports 16 (12), 3181-3194, 2016 | 97 | 2016 |
| Chronic myelogenous leukemia–initiating cells require Polycomb group protein EZH2 H Xie, C Peng, J Huang, BE Li, W Kim, EC Smith, Y Fujiwara, J Qi, ... Cancer discovery 6 (11), 1237-1247, 2016 | 89 | 2016 |
| DDI-CPI, a server that predicts drug–drug interactions through implementing the chemical–protein interactome H Luo, P Zhang, H Huang, J Huang, E Kao, L Shi, L He, L Yang Nucleic acids research 42 (W1), W46-W52, 2014 | 78 | 2014 |
| The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells S Beyaz, JH Kim, L Pinello, ME Xifaras, Y Hu, J Huang, MA Kerenyi, ... Nature immunology 18 (2), 184-195, 2017 | 68 | 2017 |
| Midlife gene expressions identify modulators of aging through dietary interventions B Zhou, L Yang, S Li, J Huang, H Chen, L Hou, J Wang, CD Green, Z Yan, ... Proceedings of the National Academy of Sciences 109 (19), E1201-E1209, 2012 | 65 | 2012 |
| Multi-scale chromatin state annotation using a hierarchical hidden Markov model E Marco, W Meuleman, J Huang, K Glass, L Pinello, J Wang, M Kellis, ... Nature communications 8 (1), 15011, 2017 | 46 | 2017 |
| Deciphering essential cistromes using genome-wide CRISPR screens T Fei, W Li, J Peng, T Xiao, CH Chen, A Wu, J Huang, C Zang, XS Liu, ... Proceedings of the National Academy of Sciences 116 (50), 25186-25195, 2019 | 39 | 2019 |
| PRMT1-mediated translation regulation is a crucial vulnerability of cancer JHR Hsu, B Hubbell-Engler, G Adelmant, J Huang, CE Joyce, F Vazquez, ... Cancer research 77 (17), 4613-4625, 2017 | 36 | 2017 |
| OTUD7B deubiquitinates LSD1 to govern its binding partner specificity, homeostasis, and breast cancer metastasis Z Gong, A Li, J Ding, Q Li, L Zhang, Y Li, Z Meng, F Chen, J Huang, ... Advanced Science 8 (15), 2004504, 2021 | 34 | 2021 |
| Enhancer dependence of cell-type–specific gene expression increases with developmental age W Cai, J Huang, Q Zhu, BE Li, D Seruggia, P Zhou, M Nguyen, Y Fujiwara, ... Proceedings of the National Academy of Sciences 117 (35), 21450-21458, 2020 | 33 | 2020 |
| Systems biology in aging: linking the old and the young L Hou, J Huang, C D Green, J Boyd-Kirkup, W Zhang, X Yu, W Gong, ... Current genomics 13 (7), 558-565, 2012 | 30 | 2012 |
| METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions Y Li, X He, X Lu, Z Gong, Q Li, L Zhang, R Yang, C Wu, J Huang, J Ding, ... Nature Communications 13 (1), 6350, 2022 | 29 | 2022 |
| Transcriptome and network changes in climbers at extreme altitudes F Chen, W Zhang, Y Liang, J Huang, K Li, CD Green, J Liu, G Zhang, ... PLoS One 7 (2), e31645, 2012 | 27 | 2012 |
| Identification of human disease genes from interactome network using graphlet interaction XD Wang, JL Huang, L Yang, DQ Wei, YX Qi, ZL Jiang PloS one 9 (1), e86142, 2014 | 24 | 2014 |
Stuart OrkinVerified email at dfci.harvard.edu
