| Potential of the conditionally replicative adenovirus Ad5-Δ24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy MLM Lamfers, J Grill, CMF Dirven, VW Van Beusechem, B Geoerger, ... Cancer research 62 (20), 5736-5742, 2002 | 249 | 2002 |
| Bone marrow gene transfer in three patients with adenosine deaminase deficiency. PM Hoogerbrugge, VW Van Beusechem, A Fischer, M Debree, F Le Deist, ... Gene therapy 3 (2), 179-183, 1996 | 231 | 1996 |
| Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells. VW van Beusechem, A Kukler, PJ Heidt, D Valerio Proceedings of the National Academy of Sciences 89 (16), 7640-7644, 1992 | 227 | 1992 |
| Targeting of adenoviral vectors through a bispecific single-chain antibody HJ Haisma, J Grill, DT Curiel, S Hoogeland, VW Van Beusechem, ... Cancer gene therapy 7 (6), 901-904, 2000 | 195 | 2000 |
| Genetic targeting of adenoviral vectors VN Krasnykh, JT Douglas, VW Van Beusechem Molecular Therapy 1 (5), 391-405, 2000 | 178 | 2000 |
| Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids J Grill, VW Van Beusechem, P Van Der Valk, CMF Dirven, A Leonhart, ... Clinical cancer research 7 (3), 641-650, 2001 | 162 | 2001 |
| Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency VW Van Beusechem, PB Van den Doel, J Grill, HM Pinedo, WR Gerritsen Cancer research 62 (21), 6165-6171, 2002 | 159 | 2002 |
| Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM HJ Haisma, HM Pinedo, A Van Rijswijk, I Van Der Meulen-Muileman, ... Gene therapy 6 (8), 1469-1474, 1999 | 155 | 1999 |
| WEE1 inhibition sensitizes osteosarcoma to radiotherapy J PosthumaDeBoer, T Würdinger, HCA Graat, VW van Beusechem, ... BMC cancer 11, 1-8, 2011 | 125 | 2011 |
| Potentiation of radiation therapy by the oncolytic adenovirus dl1520 (ONYX-015) in human malignant glioma xenografts B Geoerger, J Grill, P Opolon, J Morizet, G Aubert, Y Lecluse, ... British journal of cancer 89 (3), 577-584, 2003 | 120 | 2003 |
| Functional genetic screens identify genes essential for tumor cell survival in head and neck and lung cancer SR Martens-de Kemp, R Nagel, M Stigter-van Walsum, ... Clinical cancer research 19 (8), 1994-2003, 2013 | 119 | 2013 |
| Recombinant adenovirus vectors with knobless fibers for targeted gene transfer VW Van Beusechem, A Van Rijswijk, HHG Van Es, HJ Haisma, ... Gene Therapy 7 (22), 1940-1946, 2000 | 113 | 2000 |
| Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished VW Van Beusechem, J Grill, DCJ Mastenbroek, TJ Wickham, ... Journal of virology 76 (6), 2753-2762, 2002 | 112 | 2002 |
| Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging MLM Lamfers, G Fulci, D Gianni, Y Tang, K Kurozumi, B Kaur, ... Molecular Therapy 14 (6), 779-788, 2006 | 109 | 2006 |
| Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells JE Carette, RM Overmeer, FHE Schagen, R Alemany, OA Barski, ... Cancer Research 64 (8), 2663-2667, 2004 | 97 | 2004 |
| Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors VW Van Beusechem, DCJ Mastenbroek, PB Van den Doel, MLM Lamfers, ... Gene therapy 10 (23), 1982-1991, 2003 | 95 | 2003 |
| Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors DAM Heideman, PJF Snijders, ME Craanen, E Bloemena, CJLM Meijer, ... Cancer gene therapy 8 (5), 342-351, 2001 | 93 | 2001 |
| Oncolytic activity of p53-expressing conditionally replicative adenovirus AdΔ24-p53 against human malignant glioma B Geoerger, G Vassal, P Opolon, CMF Dirven, J Morizet, L Laudani, J Grill, ... Cancer research 64 (16), 5753-5759, 2004 | 86 | 2004 |
| Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 J Berenguer, T Lagerweij, XW Zhao, S Dusoswa, P Van Der Stoop, ... Journal of extracellular vesicles 7 (1), 1446660, 2018 | 81 | 2018 |
| The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro J Grill, MLM Lamfers, VW Van Beusechem, CM Dirven, DS Pherai, ... Molecular Therapy 6 (5), 609-614, 2002 | 79 | 2002 |
