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Leiden University Medical Center
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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
DR Burton, J Pyati, R Koduri, SJ Sharp, GB Thornton, PWHI Parren, ...
Science 266 (5187), 1024-1027, 1994
13891994
The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
F Rijsewijk, M Schuermann, E Wagenaar, P Parren, D Weigel, R Nusse
Cell 50 (4), 649-657, 1987
13021987
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design
EO Saphire, PWHI Parren, R Pantophlet, MB Zwick, GM Morris, PM Rudd, ...
science 293 (5532), 1155-1159, 2001
10282001
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
MB Zwick, AF Labrijn, M Wang, C Spenlehauer, EO Saphire, JM Binley, ...
Journal of virology 75 (22), 10892-10905, 2001
10002001
Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange
M Van Der Neut Kolfschoten, J Schuurman, M Losen, WK Bleeker, ...
Science 317 (5844), 1554-1557, 2007
9712007
Fc receptor but not complement binding is important in antibody protection against HIV
AJ Hessell, L Hangartner, M Hunter, CEG Havenith, FJ Beurskens, ...
Nature 449 (7158), 101-104, 2007
9682007
Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
M De Weers, YT Tai, MS Van Der Veer, JM Bakker, T Vink, DCH Jacobs, ...
The Journal of Immunology 186 (3), 1840-1848, 2011
9322011
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
PWHI Parren, PA Marx, AJ Hessell, A Luckay, J Harouse, C Cheng-Mayer, ...
Journal of virology 75 (17), 8340-8347, 2001
7992001
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
JL Teeling, RR French, MS Cragg, J van den Brakel, M Pluyter, H Huang, ...
Blood 104 (6), 1793-1800, 2004
7932004
The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20
JL Teeling, WJM Mackus, LJJM Wiegman, JHN van den Brakel, SA Beers, ...
The Journal of Immunology 177 (1), 362-371, 2006
7382006
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
AJ Hessell, P Poignard, M Hunter, L Hangartner, DM Tehrani, WK Bleeker, ...
Nature medicine 15 (8), 951-954, 2009
6452009
Complement is activated by IgG hexamers assembled at the cell surface
CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ...
Science 343 (6176), 1260-1263, 2014
5892014
Bispecific antibodies: a mechanistic review of the pipeline
AF Labrijn, ML Janmaat, JM Reichert, PWHI Parren
Nature reviews Drug discovery 18 (8), 585-608, 2019
5372019
On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2.
PW Parren, PA Warmerdam, LC Boeije, J Arts, NA Westerdaal, A Vlug, ...
The Journal of clinical investigation 90 (4), 1537-1546, 1992
4721992
Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1
M Hezareh, AJ Hessell, RC Jensen, JGJ van de Winkel, PWHI Parren
Journal of virology 75 (24), 12161-12168, 2001
4282001
The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity
PWHI Parren, JP Moore, DR Burton, QJ Sattentau
AIDS (Supplement) 13 (A), S137-S162, 1999
4111999
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
MB Overdijk, S Verploegen, M Bögels, M van Egmond, JJL van Bueren, ...
MAbs 7 (2), 311-320, 2015
4102015
gp120: Biologic aspects of structural features
P Poignard, EO Saphire, PWHI Parren, DR Burton
Annual review of immunology 19 (1), 253-274, 2001
3672001
Targeting interleukin‐15 in patients with rheumatoid arthritis: A proof‐of‐concept study
B Baslund, N Tvede, B Danneskiold‐Samsoe, P Larsson, G Panayi, ...
Arthritis & Rheumatism 52 (9), 2686-2692, 2005
3622005
Ebola virus can be effectively neutralized by antibody produced in natural human infection
T Maruyama, LL Rodriguez, PB Jahrling, A Sanchez, AS Khan, ST Nichol, ...
Journal of virology 73 (7), 6024-6030, 1999
3531999
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