PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42 F Martin-Belmonte, A Gassama, A Datta, W Yu, U Rescher, V Gerke, ... Cell 128 (2), 383-397, 2007 | 826 | 2007 |
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma QW Fan, ZA Knight, DD Goldenberg, W Yu, KE Mostov, D Stokoe, ... Cancer cell 9 (5), 341-349, 2006 | 762 | 2006 |
β1-integrin orients epithelial polarity via Rac1 and laminin W Yu, A Datta, P Leroy, LE O'Brien, G Mak, TS Jou, KS Matlin, KE Mostov, ... Molecular biology of the cell 16 (2), 433-445, 2005 | 412 | 2005 |
Phosphatidylinositol-3, 4, 5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells A Gassama-Diagne, W Yu, M Ter Beest, F Martin-Belmonte, A Kierbel, ... Nature cell biology 8 (9), 963-970, 2006 | 353 | 2006 |
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... Science translational medicine 13 (591), eabe7378, 2021 | 326 | 2021 |
Epithelial polarity and tubulogenesis in vitro MMP Zegers, LE O'Brien, W Yu, A Datta, KE Mostov Trends in cell biology 13 (4), 169-176, 2003 | 296 | 2003 |
Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis F Martín-Belmonte, W Yu, AE Rodríguez-Fraticelli, A Ewald, Z Werb, ... Current Biology 18 (7), 507-513, 2008 | 256 | 2008 |
A molecular switch for the orientation of epithelial cell polarization DM Bryant, J Roignot, A Datta, AW Overeem, M Kim, W Yu, X Peng, ... Developmental cell 31 (2), 171-187, 2014 | 216 | 2014 |
Cholesterol‐dependent modulation of tau phosphorylation in cultured neurons QW Fan, W Yu, T Senda, K Yanagisawa, M Michikawa Journal of neurochemistry 76 (2), 391-400, 2001 | 168 | 2001 |
Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity W Yu, AM Shewan, P Brakeman, DJ Eastburn, A Datta, DM Bryant, ... EMBO reports 9 (9), 923-929, 2008 | 152 | 2008 |
T cell circuits that sense antigen density with an ultrasensitive threshold RA Hernandez-Lopez, W Yu, KA Cabral, OA Creasey, MP Lopez Pazmino, ... Science 371 (6534), 1166-1171, 2021 | 150 | 2021 |
Cholesterol‐dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons QW Fan, W Yu, JS Gong, K Zou, N Sawamura, T Senda, K Yanagisawa, ... Journal of neurochemistry 80 (1), 178-190, 2002 | 150 | 2002 |
Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures W Yu, LE O'Brien, F Wang, H Bourne, KE Mostov, MMP Zegers Molecular biology of the cell 14 (2), 748-763, 2003 | 123 | 2003 |
Precise T cell recognition programs designed by transcriptionally linking multiple receptors JZ Williams, GM Allen, D Shah, IS Sterin, KH Kim, VP Garcia, GE Shavey, ... Science 370 (6520), 1099-1104, 2020 | 118 | 2020 |
Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis W Yu, X Fang, A Ewald, K Wong, CA Hunt, Z Werb, MA Matthay, K Mostov Molecular biology of the cell 18 (5), 1693-1700, 2007 | 110 | 2007 |
Synthetic cytokine circuits that drive T cells into immune-excluded tumors GM Allen, NW Frankel, NR Reddy, HK Bhargava, MA Yoshida, SR Stark, ... Science 378 (6625), eaba1624, 2022 | 107 | 2022 |
Polarity proteins PAR6 and aPKC regulate cell death through GSK-3β in 3D epithelial morphogenesis M Kim, A Datta, P Brakeman, W Yu, KE Mostov Journal of cell science 120 (14), 2309-2317, 2007 | 102 | 2007 |
DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation X Huang, JZ Williams, R Chang, Z Li, CE Burnett, R Hernandez-Lopez, ... Nature nanotechnology 16 (2), 214-223, 2021 | 83 | 2021 |
Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell. W Yu, T Niwa, T Fukasawa, H Hidaka, T Senda, Y Sasaki, I Niki Diabetes 49 (6), 945-952, 2000 | 74 | 2000 |
Morphological and biochemical analysis of Rac1 in three‐dimensional epithelial cell cultures LE O'Brien, W Yu, K Tang, TS Jou, MMP Zegers, KE Mostov Methods in enzymology 406, 676-691, 2006 | 64 | 2006 |