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Guilhian Leipnitz
Guilhian Leipnitz
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α-Ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain
AU Amaral, G Leipnitz, CG Fernandes, B Seminotti, PF Schuck, M Wajner
Brain research 1324, 75-84, 2010
1102010
Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro
CG Da Silva, CAJ Ribeiro, G Leipnitz, CS Dutra-Filho, ÂTS Wyse, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1586 (1), 81-91, 2002
982002
In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain
G Leipnitz, C Schumacher, KB Dalcin, K Scussiato, A Solano, C Funchal, ...
Neurochemistry international 50 (1), 83-94, 2007
972007
Evidences that maternal swimming exercise improves antioxidant defenses and induces mitochondrial biogenesis in the brain of young Wistar rats
TB Marcelino, A Longoni, KY Kudo, V Stone, A Rech, AM De Assis, ...
Neuroscience 246, 28-39, 2013
822013
Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury
V Glaser, G Leipnitz, MR Straliotto, J Oliveira, VV dos Santos, ...
Neurotoxicology 31 (5), 454-460, 2010
732010
Induction of oxidative stress by L‐2‐hydroxyglutaric acid in rat brain
A Latini, K Scussiato, R Borba Rosa, G Leipnitz, S Llesuy, A Belló‐Klein, ...
Journal of neuroscience research 74 (1), 103-110, 2003
722003
Experimental evidence that phenylalanine provokes oxidative stress in hippocampus and cerebral cortex of developing rats
CG Fernandes, G Leipnitz, B Seminotti, AU Amaral, Â Zanatta, CR Vargas, ...
Cellular and molecular neurobiology 30, 317-326, 2010
662010
3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats
A Latini, M Rodriguez, RB Rosa, K Scussiato, G Leipnitz, DR De Assis, ...
Neuroscience 135 (1), 111-120, 2005
642005
Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats
G Leipnitz, C Schumacher, K Scussiato, KB Dalcin, CMD Wannmacher, ...
International Journal of Developmental Neuroscience 23 (8), 695-701, 2005
632005
Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I …
G Leipnitz, AW Mohsen, A Karunanidhi, B Seminotti, VY Roginskaya, ...
Scientific reports 8 (1), 1165, 2018
622018
Promotion of oxidative stress by 3‐hydroxyglutaric acid in rat striatum
A Latini, K Scussiato, G Leipnitz, CS Dutra‐Filho, M Wajner
Journal of Inherited Metabolic Disease: Official Journal of the Society for …, 2005
622005
Experimental evidence that methylmalonic acid provokes oxidative damage and compromises antioxidant defenses in nerve terminal and striatum of young rats
CG Fernandes, CG Borges, B Seminotti, AU Amaral, LA Knebel, P Eichler, ...
Cellular and molecular neurobiology 31, 775-785, 2011
582011
Antioxidant properties of mesenchymal stem cells against oxidative stress in a murine model of colitis
F da Costa Gonçalves, M Grings, NS Nunes, FO Pinto, TNA Garcez, ...
Biotechnology letters 39, 613-622, 2017
572017
Inhibition of creatine kinase activity from rat cerebral cortex by D-2-hydroxyglutaric acid in vitro
CG Da Silva, ARF Bueno, PF Schuck, G Leipnitz, CAJ Ribeiro, RB Rosa, ...
Neurochemistry international 44 (1), 45-52, 2004
562004
Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers
B Seminotti, G Leipnitz, A Karunanidhi, C Kochersperger, VY Roginskaya, ...
Human molecular genetics 28 (6), 928-941, 2019
522019
Inhibition of Creatine Kinase Activity in Vitro by Ethylmalonic Acid in Cerebral Cortex of Young Rats
PF Schuck, G Leipnitz, CAJ Ribeiro, KB Dalcin, DR Assis, AG Barschak, ...
Neurochemical research 27, 1633-1639, 2002
522002
Bezafibrate prevents mitochondrial dysfunction, antioxidant system disturbance, glial reactivity and neuronal damage induced by sulfite administration in striatum of rats …
M Grings, AP Moura, B Parmeggiani, JT Pletsch, GMF Cardoso, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (9 …, 2017
492017
Physical exercise during pregnancy prevents cognitive impairment induced by amyloid-β in adult offspring rats
CP Klein, JB Hoppe, AB Saccomori, BG Dos Santos, JP Sagini, ...
Molecular neurobiology 56, 2022-2038, 2019
462019
Oxidative stress, disrupted energy metabolism, and altered signaling pathways in glutaryl-CoA dehydrogenase knockout mice: potential implications of quinolinic acid toxicity in …
B Seminotti, AU Amaral, RT Ribeiro, MDN Rodrigues, AL Colín-González, ...
Molecular neurobiology 53, 6459-6475, 2016
432016
Disturbance of brain energy and redox homeostasis provoked by sulfite and thiosulfate: potential pathomechanisms involved in the neuropathology of sulfite oxidase deficiency
M Grings, AP Moura, B Parmeggiani, GF Marcowich, AU Amaral, ...
Gene 531 (2), 191-198, 2013
422013
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