Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains JA Aten, J Stap, PM Krawczyk, CH van Oven, RA Hoebe, J Essers, ... Science 303 (5654), 92-95, 2004 | 553 | 2004 |
Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition PM Krawczyk, B Eppink, J Essers, J Stap, H Rodermond, H Odijk, ... Proceedings of the National Academy of Sciences 108 (24), 9851-9856, 2011 | 378 | 2011 |
Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all AL Oei, LEM Vriend, J Crezee, NAP Franken, PM Krawczyk Radiation Oncology 10, 1-13, 2015 | 304 | 2015 |
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma SE Mir, PCDW Hamer, PM Krawczyk, L Balaj, A Claes, JM Niers, ... Cancer cell 18 (3), 244-257, 2010 | 297 | 2010 |
Chromatin mobility is increased at sites of DNA double-strand breaks PM Krawczyk, T Borovski, J Stap, T Cijsouw, R Cate, JP Medema, ... Journal of cell science 125 (9), 2127-2133, 2012 | 161 | 2012 |
Apc-mutant cells act as supercompetitors in intestinal tumour initiation SM van Neerven, NE de Groot, LE Nijman, BP Scicluna, MS van Driel, ... Nature 594 (7863), 436-441, 2021 | 125 | 2021 |
Hyperthermia-induced DNA repair deficiency suggests novel therapeutic anti-cancer strategies B Eppink, PM Krawczyk, J Stap, R Kanaar International journal of hyperthermia 28 (6), 509-517, 2012 | 124 | 2012 |
Comparison of RBE values of high-LET α-particles for the induction of DNA-DSBs, chromosome aberrations and cell reproductive death NAP Franken, R ten Cate, PM Krawczyk, J Stap, J Haveman, J Aten, ... Radiation oncology 6, 1-8, 2011 | 113 | 2011 |
Targeting therapy-resistant cancer stem cells by hyperthermia AL Oei, LEM Vriend, PM Krawczyk, MR Horsman, NAP Franken, J Crezee International Journal of Hyperthermia 33 (4), 419-427, 2017 | 85 | 2017 |
Induction of linear tracks of DNA double-strand breaks by α-particle irradiation of cells J Stap, PM Krawczyk, CH Van Oven, GW Barendsen, J Essers, R Kanaar, ... Nature methods 5 (3), 261-266, 2008 | 79 | 2008 |
Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks LEM Vriend, R Prakash, CC Chen, F Vanoli, F Cavallo, Y Zhang, M Jasin, ... Nucleic acids research 44 (11), 5204-5217, 2016 | 69 | 2016 |
DNA double-strand breaks are not sufficient to initiate recruitment of TRF2 ES Williams, J Stap, J Essers, B Ponnaiya, MS Luijsterburg, PM Krawczyk, ... Nature genetics 39 (6), 696-698, 2007 | 67 | 2007 |
Meta-analysis of DNA double-strand break response kinetics JA Kochan, ECB Desclos, R Bosch, L Meister, LEM Vriend, H van Attikum, ... Nucleic acids research 45 (22), 12625-12637, 2017 | 61 | 2017 |
Relative biological effectiveness of high linear energy transfer α-particles for the induction of DNA-double-strand breaks, chromosome aberrations and reproductive cell death … NAP Franken, S Hovingh, R Ten Cate, P Krawczyk, J Stap, R Hoebe, ... Oncology reports 27 (3), 769-774, 2012 | 60 | 2012 |
Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining JWJ Bergs, PM Krawczyk, T Borovski, R ten Cate, HM Rodermond, J Stap, ... DNA repair 12 (1), 38-45, 2013 | 56 | 2013 |
Histatin 1 enhances cell adhesion to titanium in an implant integration model IA Van Dijk, AF Beker, W Jellema, K Nazmi, G Wu, D Wismeijer, ... Journal of dental research 96 (4), 430-436, 2017 | 55 | 2017 |
Long‐term results of 2‐mm punch grafting in patients with vitiligo vulgaris and segmental vitiligo: effect of disease activity A Fongers, A Wolkerstorfer, L Nieuweboer‐Krobotova, P Krawczyk, ... British journal of dermatology 161 (5), 1105-1111, 2009 | 46 | 2009 |
Nick-initiated homologous recombination: Protecting the genome, one strand at a time LEM Vriend, PM Krawczyk DNA repair 50, 1-13, 2017 | 40 | 2017 |
Assaying break and nick-induced homologous recombination in mammalian cells using the DR-GFP reporter and Cas9 nucleases LEM Vriend, M Jasin, PM Krawczyk Methods in enzymology 546, 175-191, 2014 | 40 | 2014 |
Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex R Prakash, T Sandoval, F Morati, JA Zagelbaum, PX Lim, T White, ... Nature communications 12 (1), 4255, 2021 | 35 | 2021 |