| Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage J Shi, R Knevel, P Suwannalai, MP van der Linden, GMC Janssen, ... Proceedings of the National Academy of Sciences 108 (42), 17372-17377, 2011 | 702 | 2011 |
| Complement activation and inhibition: a delicate balance AP Sjöberg, LA Trouw, AM Blom Trends in immunology 30 (2), 83-90, 2009 | 452 | 2009 |
| Production of complement components by cells of the immune system R Lubbers, MF Van Essen, C Van Kooten, LA Trouw Clinical & Experimental Immunology 188 (2), 183-194, 2017 | 440 | 2017 |
| Direct binding of C1q to apoptotic cells and cell blebs induces complement activation AJ Nauta, LA Trouw, MR Daha, O Tijsma, R Nieuwland, WJ Schwaeble, ... European journal of immunology 32 (6), 1726-1736, 2002 | 411 | 2002 |
| Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients H Benham, HJ Nel, SC Law, AM Mehdi, S Street, N Ramnoruth, H Pahau, ... Science translational medicine 7 (290), 290ra87-290ra87, 2015 | 374 | 2015 |
| Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes LA Trouw, TWL Groeneveld, MA Seelen, JMGJ Duijs, IM Bajema, FA Prins, ... The Journal of clinical investigation 114 (5), 679-688, 2004 | 320 | 2004 |
| Anti–cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways LA Trouw, EM Haisma, EWN Levarht, D Van Der Woude, A Ioan‐Facsinay, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 306 | 2009 |
| Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis Y Rombouts, E Ewing, LA Van De Stadt, MHJ Selman, LA Trouw, ... Annals of the rheumatic diseases 74 (1), 234-241, 2015 | 298 | 2015 |
| Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis J Shi, LA van de Stadt, EWN Levarht, TWJ Huizinga, D Hamann, ... Annals of the rheumatic diseases 73 (4), 780-783, 2014 | 271 | 2014 |
| The influence of ACPA status and characteristics on the course of RA A Willemze, LA Trouw, REM Toes, TWJ Huizinga Nature Reviews Rheumatology 8 (3), 144-152, 2012 | 267 | 2012 |
| Brief report: anti–carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis J Shi, LA van de Stadt, EWN Levarht, TWJ Huizinga, REM Toes, LA Trouw, ... Arthritis & Rheumatism 65 (4), 911-915, 2013 | 257 | 2013 |
| Glycan profiling of anti–citrullinated protein antibodies isolated from human serum and synovial fluid HU Scherer, D van der Woude, A Ioan‐Facsinay, H el Bannoudi, ... Arthritis & Rheumatism 62 (6), 1620-1629, 2010 | 257 | 2010 |
| Role of complement and complement regulators in the removal of apoptotic cells LA Trouw, AM Blom, P Gasque Molecular immunology 45 (5), 1199-1207, 2008 | 231 | 2008 |
| Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis Y Rombouts, A Willemze, JJBC van Beers, J Shi, PF Kerkman, ... Annals of the rheumatic diseases 75 (3), 578-585, 2016 | 224 | 2016 |
| Complement activation by (auto-) antibodies NA Daha, NK Banda, A Roos, FJ Beurskens, JM Bakker, MR Daha, ... Molecular immunology 48 (14), 1656-1665, 2011 | 220 | 2011 |
| The complement system as a potential therapeutic target in rheumatic disease LA Trouw, MC Pickering, AM Blom Nature Reviews Rheumatology 13 (9), 538-547, 2017 | 203 | 2017 |
| Maturation of dendritic cells abrogates C1q production in vivo and in vitro G Castellano, AM Woltman, AJ Nauta, A Roos, LA Trouw, MA Seelen, ... Blood 103 (10), 3813-3820, 2004 | 202 | 2004 |
| Age and sex-associated changes of complement activity and complement levels in a healthy Caucasian population M Gaya da Costa, F Poppelaars, C Van Kooten, TE Mollnes, F Tedesco, ... Frontiers in immunology 9, 2664, 2018 | 198 | 2018 |
| Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation W Xu, SP Berger, LA Trouw, HC de Boer, N Schlagwein, C Mutsaers, ... The Journal of Immunology 180 (11), 7613-7621, 2008 | 193 | 2008 |
| Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies X Jiang, LA Trouw, TJ van Wesemael, J Shi, C Bengtsson, H Källberg, ... Annals of the rheumatic diseases 73 (10), 1761-1768, 2014 | 181 | 2014 |
