Linda Smit
Linda Smit
Amsterdam UMC, Cancer Center Amsterdam, Location VUmc
Geverifieerd e-mailadres voor vumc.nl
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Activation of the tumour suppressor kinase LKB1 by the STE20‐like pseudokinase STRAD
AF Baas, J Boudeau, GP Sapkota, L Smit, R Medema, NA Morrice, ...
The EMBO journal 22 (12), 3062-3072, 2003
4262003
Signaling through CD44 is mediated by tyrosine kinases: association with p56lck in T lymphocytes
TEI Taher, L Smit, AW Griffioen, EJM Schilder-Tol, J Borst, ST Pals
Journal of Biological Chemistry 271 (5), 2863-2867, 1996
1971996
Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer
J Carretero, PP Medina, R Blanco, L Smit, M Tang, G Roncador, ...
Oncogene 26 (11), 1616-1625, 2007
1622007
LKB1 tumor suppressor protein: PARtaker in cell polarity
AF Baas, L Smit, H Clevers
Trends in cell biology 14 (6), 312-319, 2004
1622004
Wnt activates the Tak1/Nemo-like kinase pathway
L Smit, A Baas, J Kuipers, H Korswagen, M van de Wetering, H Clevers
Journal of Biological Chemistry 279 (17), 17232-17240, 2004
1442004
Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors
L Smit, G van der Horst, J Borst
Journal of Biological Chemistry 271 (15), 8564-8569, 1996
1241996
B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins.
L Smit, AM de Vries-Smits, JL Bos, J Borst
Journal of Biological Chemistry 269 (32), 20209-20212, 1994
1011994
Attenuation of microRNA-126 expression that drives CD34+ 38− stem/progenitor cells in acute myeloid leukemia leads to tumor eradication
DC de Leeuw, F Denkers, MC Olthof, AP Rutten, W Pouwels, ...
Cancer research 74 (7), 2094-2105, 2014
822014
The Cbl family of signal transduction molecules
L Smit, J Borst
Critical Reviews™ in Oncogenesis 8 (4), 1997
791997
Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase
GM Dingjan, A Maas, MC Nawijn, L Smit, JSA Voerman, F Grosveld, ...
The EMBO journal 17 (18), 5309-5320, 1998
661998
Binding of cell-surface expressed CD44 to hyaluronate is dependent on splicing and cell type
R Vandervoort, E Mantenhorst, L Smit, E Ostermann, F Vandenberg, ...
Biochemical and biophysical research communications 214 (1), 137-144, 1995
631995
Disruption of the SCL locus in T-lymphoid malignancies correlates with commitment to the T-cell receptor alpha beta lineage
EA Macintyre, L Smit, J Ritz, IR Kirsch, JL Strominger
611992
An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation
L Smit, K Berns, K Spence, WD Ryder, N Zeps, M Madiredjo, ...
Oncotarget 7 (3), 2596, 2016
542016
Normal hematopoietic stem cells within the AML bone marrow have a distinct and higher ALDH activity level than co-existing leukemic stem cells
GJ Schuurhuis, MH Meel, F Wouters, LA Min, M Terwijn, NA de Jonge, ...
PloS one 8 (11), e78897, 2013
542013
The fate of the three subunits of major histocompatibility complex class I molecules
JJ Neefjes, L Smit, M Gehrmann, HL Ploegh
European journal of immunology 22 (6), 1609-1614, 1992
521992
Formation of Shc/Grb2-and Crk adaptor complexes containing tyrosine phosphorylated Cbl upon stimulation of the B-cell antigen receptor.
L Smit, G van Der Horst, J Borst
Oncogene 13 (2), 381-389, 1996
501996
MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia
DC de Leeuw, W van den Ancker, F Denkers, RX de Menezes, ...
Clinical Cancer Research 19 (8), 2187-2196, 2013
442013
CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia
J Naik, M Themeli, R de Jong-Korlaar, RWJ Ruiter, PJ Poddighe, H Yuan, ...
Haematologica 104 (3), e100, 2019
372019
Primary acute myeloid leukemia cells with overexpression of EVI-1 are sensitive to all-trans retinoic acid
HJMP Verhagen, MA Smit, A Rutten, F Denkers, PJ Poddighe, PA Merle, ...
Blood, The Journal of the American Society of Hematology 127 (4), 458-463, 2016
352016
Reprogramming acute myeloid leukemia into sensitivity for retinoic-acid-driven differentiation
N van Gils, HJMP Verhagen, L Smit
Experimental hematology 52, 12-23, 2017
312017
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