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Matthijs Kox
Matthijs Kox
Assistant Professor, department of Intensive Care Medicine, Radboud University Medical Centre
Bestätigte E-Mail-Adresse bei radboudumc.nl
Titel
Zitiert von
Zitiert von
Jahr
Swarm learning for decentralized and confidential clinical machine learning
S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ...
Nature 594 (7862), 265-270, 2021
5552021
β-Glucan reverses the epigenetic state of LPS-induced immunological tolerance
B Novakovic, E Habibi, SY Wang, RJW Arts, R Davar, W Megchelenbrink, ...
Cell 167 (5), 1354-1368. e14, 2016
5442016
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ...
Nature immunology 17 (4), 406-413, 2016
5122016
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
MF Osuchowski, MS Winkler, T Skirecki, S Cajander, M Shankar-Hari, ...
The Lancet Respiratory Medicine 9 (6), 622-642, 2021
4742021
Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans
M Kox, LT Van Eijk, J Zwaag, J Van Den Wildenberg, FCGJ Sweep, ...
Proceedings of the National Academy of Sciences 111 (20), 7379-7384, 2014
3582014
Cytokine levels in critically ill patients with COVID-19 and other conditions
M Kox, NJB Waalders, EJ Kooistra, J Gerretsen, P Pickkers
Jama 324 (15), 1565-1567, 2020
3442020
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19
JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ...
Immunity 53 (6), 1296-1314. e9, 2020
2972020
Immunotherapy for the adjunctive treatment of sepsis: from immunosuppression to immunostimulation. Time for a paradigm change?
J Leentjens, M Kox, JG van der Hoeven, MG Netea, P Pickkers
American journal of respiratory and critical care medicine 187 (12), 1287-1293, 2013
2832013
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity
J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ...
Cell metabolism 29 (1), 211-220. e5, 2019
2812019
Current gaps in sepsis immunology: new opportunities for translational research
I Rubio, MF Osuchowski, M Shankar-Hari, T Skirecki, MS Winkler, ...
The Lancet infectious diseases 19 (12), e422-e436, 2019
2662019
BCG vaccination enhances the immunogenicity of subsequent influenza vaccination in healthy volunteers: a randomized, placebo-controlled pilot study
J Leentjens, M Kox, R Stokman, J Gerretsen, DA Diavatopoulos, ...
The Journal of infectious diseases 212 (12), 1930-1938, 2015
2592015
Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series
CE Delsing, MS Gresnigt, J Leentjens, F Preijers, FA Frager, M Kox, ...
BMC infectious diseases 14, 1-12, 2014
2552014
Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study
J Leentjens, M Kox, RM Koch, F Preijers, LAB Joosten, ...
American journal of respiratory and critical care medicine 186 (9), 838-845, 2012
2512012
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
AC Aschenbrenner, M Mouktaroudi, B Krämer, M Oestreich, N Antonakos, ...
Genome medicine 13, 1-25, 2021
2282021
IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1
S de Kleijn, JD Langereis, J Leentjens, M Kox, MG Netea, L Koenderman, ...
PloS one 8 (8), e72249, 2013
2212013
Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing …
M Van den Boogaard, M Kox, KL Quinn, T van Achterberg, ...
Critical care 15, 1-9, 2011
2212011
Enteroendocrine L cells sense LPS after gut barrier injury to enhance GLP-1 secretion
LJ Lebrun, K Lenaerts, D Kiers, JPP de Barros, N Le Guern, J Plesnik, ...
Cell reports 21 (5), 1160-1168, 2017
1682017
Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patients
K Timmermans, M Kox, M Vaneker, M van den Berg, A John, ...
Intensive care medicine 42, 551-561, 2016
1582016
Sepsis-induced immunoparalysis: mechanisms, markers, and treatment options
L Hamers, M Kox, P Pickkers
Minerva anestesiol 81 (4), 426-39, 2015
1562015
Precision immunotherapy for sepsis
AM Peters van Ton, M Kox, WF Abdo, P Pickkers
Frontiers in immunology 9, 412490, 2018
1542018
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