| Defining a cancer dependency map A Tsherniak, F Vazquez, PG Montgomery, BA Weir, G Kryukov, ... Cell 170 (3), 564-576. e16, 2017 | 1997 | 2017 |
| Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ... Nature genetics 49 (12), 1779-1784, 2017 | 1518 | 2017 |
| Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt Nature biotechnology 33 (2), 179-186, 2015 | 741 | 2015 |
| Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ... Cancer discovery 6 (8), 914-929, 2016 | 643 | 2016 |
| Multimodal analysis of composition and spatial architecture in human squamous cell carcinoma AL Ji, AJ Rubin, K Thrane, S Jiang, DL Reynolds, RM Meyers, MG Guo, ... Cell 182 (2), 497-514. e22, 2020 | 619 | 2020 |
| Microbial colonization influences early B-lineage development in the gut lamina propria DR Wesemann, AJ Portuguese, RM Meyers, MP Gallagher, K Cluff-Jones, ... Nature 501 (7465), 112-115, 2013 | 307 | 2013 |
| Long neural genes harbor recurrent DNA break clusters in neural stem/progenitor cells PC Wei, AN Chang, J Kao, Z Du, RM Meyers, FW Alt, B Schwer Cell 164 (4), 644-655, 2016 | 259 | 2016 |
| Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability FL Meng, Z Du, A Federation, J Hu, Q Wang, KR Kieffer-Kwon, ... Cell 159 (7), 1538-1548, 2014 | 259 | 2014 |
| Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing J Hu, RM Meyers, J Dong, RA Panchakshari, FW Alt, RL Frock Nature protocols 11 (5), 853-871, 2016 | 219 | 2016 |
| Sequence-intrinsic mechanisms that target AID mutational outcomes on antibody genes LS Yeap, JK Hwang, Z Du, RM Meyers, FL Meng, A Jakubauskaitė, M Liu, ... Cell 163 (5), 1124-1137, 2015 | 171 | 2015 |
| Chromosomal loop domains direct the recombination of antigen receptor genes J Hu, Y Zhang, L Zhao, RL Frock, Z Du, RM Meyers, F Meng, DG Schatz, ... Cell 163 (4), 947-959, 2015 | 155 | 2015 |
| CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ... The Journal of clinical investigation 128 (1), 446-462, 2018 | 135 | 2018 |
| Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens J Pan, RM Meyers, BC Michel, N Mashtalir, AE Sizemore, JN Wells, ... Cell systems 6 (5), 555-568. e7, 2018 | 133 | 2018 |
| Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells B Schwer, PC Wei, AN Chang, J Kao, Z Du, RM Meyers, FW Alt Proceedings of the National Academy of Sciences 113 (8), 2258-2263, 2016 | 114 | 2016 |
| Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching J Dong, RA Panchakshari, T Zhang, Y Zhang, J Hu, SA Volpi, RM Meyers, ... Nature 525 (7567), 134-139, 2015 | 109 | 2015 |
| A genome-wide atlas of co-essential modules assigns function to uncharacterized genes M Wainberg, RA Kamber, A Balsubramani, RM Meyers, ... Nature genetics 53 (5), 638-649, 2021 | 107 | 2021 |
| Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ... Nature communications 9 (1), 2024, 2018 | 93 | 2018 |
| Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting. Cancer Discov. 2016; 6: 914–929. doi: 10.1158/2159-8290 AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ... CD-16-0154.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 56 | |
| Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies JK Hwang, C Wang, Z Du, RM Meyers, TB Kepler, D Neuberg, PD Kwong, ... Proceedings of the National Academy of Sciences 114 (32), 8614-8619, 2017 | 50 | 2017 |
| IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances M Gostissa, B Schwer, A Chang, J Dong, RM Meyers, GT Marecki, ... Proceedings of the National Academy of Sciences 111 (7), 2644-2649, 2014 | 42 | 2014 |
Aviad TsherniakBroad Institute of Harvard and MITVerified email at broadinstitute.org
