Bryan R. G. Williams
Bryan R. G. Williams
Emeritus Director and Distinguished Scientist, Hudson Institute of Medical Research
Verified email at - Homepage
Cited by
Cited by
How cells respond to interferons
GR Stark, IM Kerr, BRG Williams, RH Silverman, RD Schreiber
Annual review of biochemistry 67 (1), 227-264, 1998
Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays
SD Der, A Zhou, BRG Williams, RH Silverman
Proceedings of the National Academy of Sciences 95 (26), 15623-15628, 1998
Interferon-inducible antiviral effectors
AJ Sadler, BRG Williams
Nature reviews immunology 8 (7), 559-568, 2008
Activation of the interferon system by short-interfering RNAs
CA Sledz, M Holko, MJ De Veer, RH Silverman, BRG Williams
Nature cell biology 5 (9), 834-839, 2003
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
E Meurs, K Chong, J Galabru, NSB Thomas, IM Kerr, BRG Williams, ...
Cell 62 (2), 379-390, 1990
Functional classification of interferon‐stimulated genes identified using microarrays
MJ De Veer, M Holko, M Frevel, E Walker, S Der, JM Paranjape, ...
Journal of leukocyte biology 69 (6), 912-920, 2001
PKR; a sentinel kinase for cellular stress
BRG Williams
Oncogene 18 (45), 6112-6120, 1999
Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis
M Chawla-Sarkar, DJ Lindner, YF Liu, BR Williams, GC Sen, ...
Apoptosis 8 (3), 237-249, 2003
TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages
V Toshchakov, BW Jones, PY Perera, K Thomas, MJ Cody, S Zhang, ...
Nature immunology 3 (4), 392-398, 2002
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase.
YL Yang, LF Reis, J Pavlovic, A Aguzzi, R Schäfer, A Kumar, BR Williams, ...
The EMBO journal 14 (24), 6095-6106, 1995
Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B
A Kumar, J Haque, J Lacoste, J Hiscott, BR Williams
Proceedings of the National Academy of Sciences 91 (14), 6288-6292, 1994
Biological properties of recombinant α-interferons: 40th anniversary of the discovery of interferons
LM Pfeffer, CA Dinarello, RB Herberman, BRG Williams, EC Borden, ...
Cancer research 58 (12), 2489-2499, 1998
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
SD Der, YL Yang, C Weissmann, BRG Williams
Proceedings of the National Academy of Sciences 94 (7), 3279-3283, 1997
Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts
MJ Clemens, BRG Williams
Cell 13 (3), 565-572, 1978
Signal integration via PKR
BRG Williams
Science's STKE 2001 (89), re2-re2, 2001
JNK2 and IKKβ are required for activating the innate response to viral infection
WM Chu, D Ostertag, ZW Li, L Chang, Y Chen, Y Hu, B Williams, ...
Immunity 11 (6), 721-731, 1999
ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins
T Bakheet, M Frevel, BRG Williams, W Greer, KSA Khabar
Nucleic acids research 29 (1), 246-254, 2001
A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells
JT Marques, T Devosse, D Wang, M Zamanian-Daryoush, P Serbinowski, ...
Nature biotechnology 24 (5), 559-565, 2006
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
KC Goh, SJ Haque, BRG Williams
The EMBO journal 18 (20), 5601-5608, 1999
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF‐1 and NF‐κB
A Kumar, YL Yang, V Flati, S Der, S Kadereit, A Deb, J Haque, L Reis, ...
The EMBO journal 16 (2), 406-416, 1997
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