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Brendon Scicluna
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Year
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk, BP Scicluna, MG Netea
Nature Reviews Immunology 17 (7), 407-420, 2017
14702017
The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
TJ Schuijt, JM Lankelma, BP Scicluna, FS e Melo, JJTH Roelofs, ...
Gut 65 (4), 575-583, 2016
7252016
Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis
LA van Vught, PMCK Klouwenberg, C Spitoni, BP Scicluna, MA Wiewel, ...
Jama 315 (14), 1469-1479, 2016
5132016
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ...
Nature immunology 17 (4), 406-413, 2016
5122016
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study
BP Scicluna, LA Van Vught, AH Zwinderman, MA Wiewel, EE Davenport, ...
The Lancet Respiratory Medicine 5 (10), 816-826, 2017
4172017
Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients
TAM Claushuis, LA van Vught, BP Scicluna, MA Wiewel, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3062-3072, 2016
2912016
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity
J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ...
Cell metabolism 29 (1), 211-220. e5, 2019
2802019
Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction
CR Bezzina, R Pazoki, A Bardai, RF Marsman, JSSG De Jong, MT Blom, ...
Nature genetics 42 (8), 688-691, 2010
2372010
Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy
K Pilichou, CA Remme, C Basso, ME Campian, S Rizzo, P Barnett, ...
Journal of Experimental Medicine 206 (8), 1787-1802, 2009
2232009
A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission
BP Scicluna, PMC Klein Klouwenberg, LA van Vught, MA Wiewel, ...
American journal of respiratory and critical care medicine 192 (7), 826-835, 2015
1972015
A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients: discovery and validation in independent …
L McHugh, TA Seldon, RA Brandon, JT Kirk, A Rapisarda, AJ Sutherland, ...
PLoS medicine 12 (12), e1001916, 2015
1872015
Biomarkers in sepsis
TSR Van Engelen, WJ Wiersinga, BP Scicluna, T van der Poll
Critical care clinics 34 (1), 139-152, 2018
1752018
Functional NaV1.8 Channels in Intracardiac Neurons: The Link Between SCN10A and Cardiac Electrophysiology
AO Verkerk, CA Remme, CA Schumacher, BP Scicluna, R Wolswinkel, ...
Circulation research 111 (3), 333-343, 2012
1652012
36th international symposium on intensive care and emergency medicine: Brussels, Belgium. 15-18 March 2016
RM Bateman, MD Sharpe, JE Jagger, CG Ellis, J Solé-Violán, ...
Critical care 20, 13-182, 2016
1462016
The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium
CA Remme, AO Verkerk, WMH Hoogaars, WTJ Aanhaanen, BP Scicluna, ...
Basic research in cardiology 104, 511-522, 2009
1332009
Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice
L Fabritz, MG Hoogendijk, BP Scicluna, SCM Van Amersfoorth, ...
Journal of the American College of Cardiology 57 (6), 740-750, 2011
1312011
Apc-mutant cells act as supercompetitors in intestinal tumour initiation
SM van Neerven, NE de Groot, LE Nijman, BP Scicluna, MS van Driel, ...
Nature 594 (7863), 436-441, 2021
1242021
Admission hyperglycemia in critically ill sepsis patients: association with outcome and host response
LA van Vught, MA Wiewel, PMCK Klouwenberg, AJ Hoogendijk, ...
Critical care medicine 44 (7), 1338-1346, 2016
1172016
Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profiles
LDJ Bos, BP Scicluna, DSY Ong, O Cremer, T van Der Poll, MJ Schultz
American journal of respiratory and critical care medicine 200 (1), 42-50, 2019
1112019
Myocardial injury in patients with sepsis and its association with long-term outcome
JF Frencken, DW Donker, C Spitoni, ME Koster-Brouwer, IW Soliman, ...
Circulation: Cardiovascular Quality and Outcomes 11 (2), e004040, 2018
1042018
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