Type IIA topoisomerase inhibition by a new class of antibacterial agents BD Bax, PF Chan, DS Eggleston, A Fosberry, DR Gentry, F Gorrec, ... Nature 466 (7309), 935-940, 2010 | 824 | 2010 |
DABSO-based, three-component, one-pot sulfone synthesis AS Deeming, CJ Russell, AJ Hennessy, MC Willis Organic letters 16 (1), 150-153, 2014 | 211 | 2014 |
Synthesis of diverse macrocyclic peptidomimetics utilizing ring-closing metathesis and solid-phase synthesis AGM Barrett, AJ Hennessy, RL Vézouët, PA Procopiou, PW Seale, ... The Journal of organic chemistry 69 (4), 1028-1037, 2004 | 76 | 2004 |
Oxazole synthesis with minimal purification: Synthesis and application of a rompgel tosmic reagent AGM Barrett, SM Cramp, AJ Hennessy, PA Procopiou, RS Roberts Organic Letters 3 (2), 271-273, 2001 | 69 | 2001 |
2, 2-Dimethyl-2, 3-dihydrofuran, a new substrate for intermolecular asymmetric Heck reactions AJ Hennessy, YM Malone, PJ Guiry Tetrahedron letters 40 (51), 9163-9166, 1999 | 66 | 1999 |
Novel hydroxyl tricyclics (eg, GSK966587) as potent inhibitors of bacterial type IIA topoisomerases TJ Miles, AJ Hennessy, B Bax, G Brooks, BS Brown, P Brown, N Cailleau, ... Bioorganic & medicinal chemistry letters 23 (19), 5437-5441, 2013 | 65 | 2013 |
The asymmetric Heck reaction: recent developments and applications of new palladium diphenylphosphinopyrrolidine complexes PJ Guiry, AJ Hennessy, JP Cahill Topics in Catalysis 4, 311-326, 1997 | 63 | 1997 |
Double Gold‐Catalysed Annulation of Indoles by Enynones SJ Heffernan, JP Tellam, ME Queru, AC Silvanus, D Benito, MF Mahon, ... Advanced Synthesis & Catalysis 355 (6), 1149-1159, 2013 | 61 | 2013 |
From 2, 3-dihydrofuran to 2, 2-dialkyl-2, 3-dihydrofurans: new substrates for the intermolecular asymmetric Heck reaction TG Kilroy, AJ Hennessy, DJ Connolly, YM Malone, A Farrell, PJ Guiry Journal of Molecular Catalysis A: Chemical 196 (1-2), 65-81, 2003 | 58 | 2003 |
Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases TJ Miles, C Barfoot, G Brooks, P Brown, D Chen, S Dabbs, DT Davies, ... Bioorganic & medicinal chemistry letters 21 (24), 7483-7488, 2011 | 54 | 2011 |
Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases TJ Miles, JM Axten, C Barfoot, G Brooks, P Brown, D Chen, S Dabbs, ... Bioorganic & medicinal chemistry letters 21 (24), 7489-7495, 2011 | 53 | 2011 |
Intermolecular asymmetric Heck reactions with 2, 2-diethyl-2, 3-dihydrofuran AJ Hennessy, DJ Connolly, YM Malone, PJ Guiry Tetrahedron Letters 41 (40), 7757-7761, 2000 | 52 | 2000 |
Novel tricyclics (eg, GSK945237) as potent inhibitors of bacterial type IIA topoisomerases TJ Miles, AJ Hennessy, B Bax, G Brooks, BS Brown, P Brown, N Cailleau, ... Bioorganic & medicinal chemistry letters 26 (10), 2464-2469, 2016 | 48 | 2016 |
Target-directed synthesis of antibacterial drug candidate GSK966587 EA Voight, H Yin, SV Downing, SA Calad, H Matsuhashi, I Giordano, ... Organic Letters 12 (15), 3422-3425, 2010 | 39 | 2010 |
The asymmetric cyclohexenylation of 2, 2-dimethyl-2, 3-dihydrofuran AJ Hennessy, YM Malone, PJ Guiry Tetrahedron Letters 41 (13), 2261-2264, 2000 | 35 | 2000 |
Gold-catalysed cascade rearrangements of ynamide propargyl esters SJ Heffernan, JM Beddoes, MF Mahon, AJ Hennessy, DR Carbery Chemical Communications 49 (23), 2314-2316, 2013 | 34 | 2013 |
Advances in structure-based drug design of novel bacterial topoisomerase inhibitors K Widdowson, A Hennessy Future medicinal chemistry 2 (11), 1619-1622, 2010 | 28 | 2010 |
Iron-mediated C–H coupling of arenes and unactivated terminal alkenes directed by sulfur CW Cavanagh, MH Aukland, A Hennessy, DJ Procter Chemical communications 51 (45), 9272-9275, 2015 | 20 | 2015 |
Flexible palladium-catalysed amidation reactions for the synthesis of complex aryl amides C Barfoot, G Brooks, P Brown, S Dabbs, DT Davies, I Giordano, ... Tetrahedron Letters 51 (20), 2685-2689, 2010 | 20 | 2010 |
The design of efficient and selective routes to pyridyl analogues of 3-oxo-3, 4-dihydro-2H-1, 4-(benzothiazine or benzoxazine)-6-carbaldehydes G Brooks, S Dabbs, DT Davies, AJ Hennessy, GE Jones, RE Markwell, ... Tetrahedron Letters 51 (38), 5035-5037, 2010 | 19 | 2010 |