| Tumor metastasis: moving new biological insights into the clinic L Wan, K Pantel, Y Kang Nature medicine 19 (11), 1450-1464, 2013 | 813 | 2013 |
| Molecular coupling of histone crotonylation and active transcription by AF9 YEATS domain Y Li, BR Sabari, T Panchenko, H Wen, D Zhao, H Guan, L Wan, H Huang, ... Molecular cell 62 (2), 181-193, 2016 | 318 | 2016 |
| ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia L Wan, H Wen, Y Li, J Lyu, Y Xi, T Hoshii, JK Joseph, X Wang, YHE Loh, ... Nature 543 (7644), 265-269, 2017 | 239 | 2017 |
| MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene-and carcinogen-induced mammary tumors L Wan, X Lu, S Yuan, Y Wei, F Guo, M Shen, M Yuan, R Chakrabarti, ... Cancer cell 26 (1), 92-105, 2014 | 125 | 2014 |
| Impaired cell fate through gain-of-function mutations in a chromatin reader L Wan, S Chong, F Xuan, A Liang, X Cui, L Gates, TS Carroll, Y Li, L Feng, ... Nature 577 (7788), 121-126, 2020 | 97 | 2020 |
| Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking X Li, XM Li, Y Jiang, Z Liu, Y Cui, KY Fung, SHE van der Beelen, G Tian, ... Nature chemical biology 14 (12), 1140-1149, 2018 | 85 | 2018 |
| The endoplasmic reticulum acts as a platform for ubiquitylated components of nuclear factor κB signaling C Alexia, K Poalas, G Carvalho, N Zemirli, J Dwyer, SM Dubois, ... Science signaling 6 (291), ra79-ra79, 2013 | 53 | 2013 |
| Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer L Wan, Y Kang Advances in cancer research 120, 113-134, 2013 | 46 | 2013 |
| Therapeutic targeting of metadherin suppresses colorectal and lung cancer progression and metastasis M Shen, S Xie, M Rowicki, S Michel, Y Wei, X Hang, L Wan, X Lu, M Yuan, ... Cancer research 81 (4), 1014-1025, 2021 | 40 | 2021 |
| Structural insights into the tumor-promoting function of the MTDH-SND1 complex F Guo, L Wan, A Zheng, V Stanevich, Y Wei, KA Satyshur, M Shen, W Lee, ... Cell reports 8 (6), 1704-1713, 2014 | 39 | 2014 |
| Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis L Wan, G Hu, Y Wei, M Yuan, RT Bronson, Q Yang, J Siddiqui, KJ Pienta, ... Cancer research 74 (18), 5336-5347, 2014 | 39 | 2014 |
| KAT6A and ENL form an epigenetic transcriptional control module to drive critical leukemogenic gene-expression programs F Yan, J Li, J Milosevic, R Petroni, S Liu, Z Shi, S Yuan, JM Reynaga, Y Qi, ... Cancer discovery 12 (3), 792-811, 2022 | 38 | 2022 |
| Pharmacological disruption of the MTDH–SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer M Shen, HA Smith, Y Wei, YZ Jiang, S Zhao, N Wang, M Rowicki, Y Tang, ... Nature cancer 3 (1), 60-74, 2022 | 27 | 2022 |
| Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer L Song, X Yao, H Li, B Peng, AP Boka, Y Liu, G Chen, Z Liu, KM Mathias, ... Molecular cell 82 (21), 4080-4098. e12, 2022 | 26 | 2022 |
| Small-molecule inhibitors that disrupt the MTDH–SND1 complex suppress breast cancer progression and metastasis M Shen, Y Wei, H Kim, L Wan, YZ Jiang, X Hang, M Raba, S Remiszewski, ... Nature cancer 3 (1), 43-59, 2022 | 25 | 2022 |
| Small-molecule inhibition of the acyl-lysine reader ENL as a strategy against acute myeloid leukemia Y Liu, Q Li, F Alikarami, DR Barrett, L Mahdavi, H Li, S Tang, TA Khan, ... Cancer discovery 12 (11), 2684-2709, 2022 | 24 | 2022 |
| Mutant NPM1 hijacks transcriptional hubs to maintain pathogenic gene programs in acute myeloid leukemia XQD Wang, D Fan, Q Han, Y Liu, H Miao, X Wang, Q Li, D Chen, H Gore, ... Cancer discovery 13 (3), 724-745, 2023 | 22 | 2023 |
| Use of peptides that block metadherin-SND1 interaction as treatment for cancer Y Kang, Y Xing, L Wan, F Guo US Patent 10,357,539, 2019 | 2 | 2019 |
| Charles David Allis (1951–2023) P Chi, PW Lewis, C Lu, J Lu, AJ Ruthenburg, BR Sabari, D Shechter, ... Nature genetics 55 (4), 522-523, 2023 | 1 | 2023 |
| Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055 M Michino, TA Khan, MW Miller, Y Fukase, J Vendome, C Adura, ... ACS Medicinal Chemistry Letters, 2024 | | 2024 |
