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Peter R Shepherd
Peter R Shepherd
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Geverifieerd e-mailadres voor auckland.ac.nz
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Glucose transporters and insulin action—implications for insulin resistance and diabetes mellitus
PR Shepherd, BB Kahn
New England journal of medicine 341 (4), 248-257, 1999
19501999
The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins
LS Harrington, GM Findlay, A Gray, T Tolkacheva, S Wigfield, H Rebholz, ...
The Journal of cell biology 166 (2), 213-223, 2004
13782004
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
PR Shepherd, DJ Withers, K Siddle
Biochemical Journal 333 (3), 471-490, 1998
12521998
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
PR Shepherd, DJ Withers, K Siddle
Biochemical Journal 333 (3), 471-490, 1998
12521998
Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on …
BT Navé, DM Ouwens, DJ Withers, DR Alessi, PR SHEPHERD
Biochemical Journal 344 (2), 427-431, 1999
12211999
PI 3-kinase p110β: a new target for antithrombotic therapy
SP Jackson, SM Schoenwaelder, I Goncalves, WS Nesbitt, CL Yap, ...
Nature medicine 11 (5), 507-514, 2005
7252005
Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue.
PR Shepherd, L Gnudi, E Tozzo, H Yang, F Leach, BB Kahn
Journal of Biological Chemistry 268 (30), 22243-22246, 1993
6471993
Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance
VA Hughes, MA Fiatarone, RA Fielding, BB Kahn, CM Ferrara, ...
American Journal of Physiology-Endocrinology and Metabolism 264 (6), E855-E862, 1993
4651993
Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status
SWY Cheng, LGD Fryer, D Carling, PR Shepherd
Journal of Biological Chemistry 279 (16), 15719-15722, 2004
4122004
The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019
KB Tran, JJ Lang, K Compton, R Xu, AR Acheson, HJ Henrikson, ...
The Lancet 400 (10352), 563-591, 2022
3802022
Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of …
PR Shepherd, BT Nave, K Siddle
Biochemical Journal 305 (1), 25-28, 1995
3231995
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
C Chaussade, GW Rewcastle, JD Kendall, WA Denny, K Cho, ...
Biochemical Journal 404 (3), 449-458, 2007
2592007
The role of phosphoinositide 3-kinase C2α in insulin signaling
M Falasca, WE Hughes, V Dominguez, G Sala, F Fostira, MQ Fang, ...
Journal of Biological Chemistry 282 (38), 28226-28236, 2007
2022007
Altered adipocyte properties in the offspring of protein malnourished rats
PR Shepherd, NJ Crowther, M Desai, CN Hales, SE Ozanne
British Journal of Nutrition 78 (1), 121-129, 1997
2001997
Mechanisms regulating phosphoinositide 3‐kinase signalling in insulin‐sensitive tissues
PR Shepherd
Acta Physiologica Scandinavica 183 (1), 3-12, 2005
1972005
Insulin activates the α isoform of class II phosphoinositide 3-kinase
RA Brown, J Domin, A Arcaro, MD Waterfield, PR Shepherd
Journal of Biological Chemistry 274 (21), 14529-14532, 1999
1831999
Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes
SE Ozanne, BT Nave, CL Wang, PR Shepherd, J Prins, GD Smith
American Journal of Physiology-Endocrinology And Metabolism 273 (1), E46-E51, 1997
1831997
A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types
S Jamieson, JU Flanagan, S Kolekar, C Buchanan, JD Kendall, WJ Lee, ...
Biochemical Journal 438 (1), 53-62, 2011
1762011
Direct effects of caffeine and theophylline on p110δ and other phosphoinositide 3-kinases: differential effects on lipid kinase and protein kinase activities
LC Foukas, N Daniele, C Ktori, KE Anderson, J Jensen, PR Shepherd
Journal of Biological Chemistry 277 (40), 37124-37130, 2002
1702002
G protein–coupled receptor–mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness
HA Dbouk, O Vadas, A Shymanets, JE Burke, RS Salamon, BD Khalil, ...
Science signaling 5 (253), ra89-ra89, 2012
1672012
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