Dll1+ secretory progenitor cells revert to stem cells upon crypt damage JH Van Es, T Sato, M Van De Wetering, A Lyubimova, AN Yee Nee, ... Nature cell biology 14 (10), 1099-1104, 2012 | 875 | 2012 |
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma MB Overdijk, S Verploegen, M Bögels, M van Egmond, JJL van Bueren, ... MAbs 7 (2), 311-320, 2015 | 549 | 2015 |
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids JML Roodhart, LGM Daenen, ECA Stigter, HJ Prins, J Gerrits, ... Cancer cell 20 (3), 370-383, 2011 | 385 | 2011 |
Target antigen density governs the efficacy of anti–CD20-CD28-CD3 ζ chimeric antigen receptor–modified effector CD8+ T cells K Watanabe, S Terakura, AC Martens, T Van Meerten, S Uchiyama, ... The Journal of Immunology 194 (3), 911-920, 2015 | 319 | 2015 |
Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab IS Nijhof, RWJ Groen, HM Lokhorst, B Van Kessel, AC Bloem, ... Leukemia 29 (10), 2039-2049, 2015 | 312 | 2015 |
A rational strategy for reducing on-target off-tumor effects of CD38-chimeric antigen receptors by affinity optimization E Drent, M Themeli, R Poels, R de Jong-Korlaar, H Yuan, J de Bruijn, ... Molecular therapy 25 (8), 1946-1958, 2017 | 288 | 2017 |
Peyer's patch M cells derived from Lgr5+ stem cells require SpiB and are induced by RankL in cultured “miniguts” W de Lau, P Kujala, K Schneeberger, S Middendorp, VSW Li, N Barker, ... Molecular and cellular biology, 2012 | 285 | 2012 |
cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo R Siddappa, A Martens, J Doorn, A Leusink, C Olivo, R Licht, L Van Rijn, ... Proceedings of the National Academy of Sciences 105 (20), 7281-7286, 2008 | 266 | 2008 |
Bone-marrow-derived cells contribute to glomerular endothelial repair in experimental glomerulonephritis MB Rookmaaker, AM Smits, H Tolboom, K Van't Wout, AC Martens, ... The American journal of pathology 163 (2), 553-562, 2003 | 243 | 2003 |
A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/-γc-/-double-mutant mice RS van Rijn, ER Simonetti, A Hagenbeek, MCH Hogenes, RA de Weger, ... Blood 102 (7), 2522-2531, 2003 | 228 | 2003 |
Safety of retroviral gene marking with a truncated NGF receptor C Bonini, M Grez, C Traversari, F Ciceri, S Marktel, G Ferrari, M Dinauer, ... Nature medicine 9 (4), 367-369, 2003 | 203 | 2003 |
Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma E Drent, RWJ Groen, WA Noort, M Themeli, JJL van Bueren, PWHI Parren, ... haematologica 101 (5), 616, 2016 | 201 | 2016 |
Preclinical evidence for the therapeutic potential of CD38-targeted immuno-chemotherapy in multiple myeloma patients refractory to lenalidomide and bortezomib IS Nijhof, RWJ Groen, WA Noort, B van Kessel, R de Jong-Korlaar, ... Clinical cancer research 21 (12), 2802-2810, 2015 | 186 | 2015 |
In vitro induction of alkaline phosphatase levels predicts in vivo bone forming capacity of human bone marrow stromal cells HJ Prins, AK Braat, D Gawlitta, WJA Dhert, DA Egan, E Tijssen-Slump, ... Stem cell research 12 (2), 428-440, 2014 | 179 | 2014 |
Redirecting αβT cells against cancer cells by transfer of a broadly tumor-reactive γδT-cell receptor V Marcu-Malina, S Heijhuurs, M van Buuren, L Hartkamp, S Strand, ... Blood, The Journal of the American Society of Hematology 118 (1), 50-59, 2011 | 165 | 2011 |
Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma RWJ Groen, WA Noort, RA Raymakers, HJ Prins, L Aalders, FM Hofhuis, ... Blood, The Journal of the American Society of Hematology 120 (3), e9-e16, 2012 | 163 | 2012 |
In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling S de Haij, JHM Jansen, P Boross, FJ Beurskens, JE Bakema, DL Bos, ... Cancer research 70 (8), 3209-3217, 2010 | 157 | 2010 |
Non-canonical PRC1. 1 targets active genes independent of H3K27me3 and is essential for leukemogenesis V van den Boom, H Maat, M Geugien, AR López, AM Sotoca, J Jaques, ... Cell reports 14 (2), 332-346, 2016 | 156 | 2016 |
Prospective isolation of mesenchymal stem cells from multiple mammalian species using cross-reacting anti-human monoclonal antibodies H Rozemuller, HJ Prins, B Naaijkens, J Staal, HJ Bühring, AC Martens Stem cells and development 19 (12), 1911-1921, 2010 | 127 | 2010 |
CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia J Naik, M Themeli, R de Jong-Korlaar, RWJ Ruiter, PJ Poddighe, H Yuan, ... Haematologica 104 (3), e100, 2019 | 122 | 2019 |