Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool P Reddy, L Liu, D Adhikari, K Jagarlamudi, S Rajareddy, Y Shen, C Du, ... Science 319 (5863), 611-613, 2008 | 938 | 2008 |
In vivo amelioration of age-associated hallmarks by partial reprogramming A Ocampo, P Reddy, P Martinez-Redondo, A Platero-Luengo, F Hatanaka, ... Cell 167 (7), 1719-1733. e12, 2016 | 744 | 2016 |
Interspecies chimerism with mammalian pluripotent stem cells J Wu, A Platero-Luengo, M Sakurai, A Sugawara, MA Gil, T Yamauchi, ... Cell 168 (3), 473-486. e15, 2017 | 550 | 2017 |
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging W Zhang, J Li, K Suzuki, J Qu, P Wang, J Zhou, X Liu, R Ren, X Xu, ... Science 348 (6239), 1160-1163, 2015 | 511 | 2015 |
In vivo target gene activation via CRISPR/Cas9-mediated trans-epigenetic modulation HK Liao, F Hatanaka, T Araoka, P Reddy, MZ Wu, Y Sui, T Yamauchi, ... Cell 171 (7), 1495-1507. e15, 2017 | 430 | 2017 |
Selective elimination of mitochondrial mutations in the germline by genome editing P Reddy, A Ocampo, K Suzuki, J Luo, SR Bacman, SL Williams, ... Cell 161 (3), 459-469, 2015 | 305 | 2015 |
Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a L Liu, S Rajareddy, P Reddy, C Du, K Jagarlamudi, Y Shen, ... Oxford University Press for The Company of Biologists Limited 134 (1), 199-209, 2007 | 292 | 2007 |
Mechanisms maintaining the dormancy and survival of mammalian primordial follicles P Reddy, W Zheng, K Liu Trends in Endocrinology & Metabolism 21 (2), 96-103, 2010 | 275 | 2010 |
Control of mammalian oocyte growth and early follicular development by the oocyte PI3 kinase pathway: new roles for an old timer K Liu, S Rajareddy, L Liu, K Jagarlamudi, K Boman, G Selstam, P Reddy Developmental biology 299 (1), 1-11, 2006 | 260 | 2006 |
PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles P Reddy, D Adhikari, W Zheng, S Liang, T Hämäläinen, V Tohonen, ... Human molecular genetics 18 (15), 2813-2824, 2009 | 257 | 2009 |
Activation of Akt (PKB) and suppression of FKHRL1 in mouse and rat oocytes by stem cell factor during follicular activation and development P Reddy, L Shen, C Ren, K Boman, E Lundin, U Ottander, P Lindgren, ... Developmental biology 281 (2), 160-170, 2005 | 231 | 2005 |
Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development L Kurian, A Aguirre, I Sancho-Martinez, C Benner, T Hishida, TB Nguyen, ... Circulation 131 (14), 1278-1290, 2015 | 211 | 2015 |
p27kip1 (Cyclin-Dependent Kinase Inhibitor 1B) Controls Ovarian Development by Suppressing Follicle Endowment and Activation and Promoting Follicle Atresia … S Rajareddy, P Reddy, C Du, L Liu, K Jagarlamudi, W Tang, Y Shen, ... Molecular endocrinology 21 (9), 2189-2202, 2007 | 175 | 2007 |
Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation K Jagarlamudi, L Liu, D Adhikari, P Reddy, A Idahl, U Ottander, E Lundin, ... PloS one 4 (7), e6186, 2009 | 161 | 2009 |
Formation of E-cadherin-mediated cell-cell adhesion activates AKT and mitogen activated protein kinase via phosphatidylinositol 3 kinase and ligand-independent activation of … P Reddy, L Liu, C Ren, P Lindgren, K Boman, Y Shen, E Lundin, ... Molecular Endocrinology 19 (10), 2564-2578, 2005 | 159 | 2005 |
Single-dose CRISPR–Cas9 therapy extends lifespan of mice with Hutchinson–Gilford progeria syndrome E Beyret, HK Liao, M Yamamoto, R Hernandez-Benitez, Y Fu, G Erikson, ... Nature medicine 25 (3), 419-422, 2019 | 154 | 2019 |
In vivo reprogramming of wound-resident cells generates skin epithelial tissue M Kurita, T Araoka, T Hishida, DD O’keefe, Y Takahashi, A Sakamoto, ... Nature 561 (7722), 243-247, 2018 | 124 | 2018 |
In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice KC Browder, P Reddy, M Yamamoto, A Haghani, IG Guillen, S Sahu, ... Nature Aging 2 (3), 243-253, 2022 | 118 | 2022 |
Universal DNA methylation age across mammalian tissues AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li, R Lowe, Q Yan, ... BioRxiv, 2021.01. 18.426733, 2021 | 104 | 2021 |
Genetically modified mouse models for premature ovarian failure (POF) K Jagarlamudi, P Reddy, D Adhikari, K Liu Molecular and cellular endocrinology 315 (1-2), 1-10, 2010 | 88 | 2010 |