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John S Philo
John S Philo
Alliance Protein Laboratories
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Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions
J Wen, T Arakawa, JS Philo
Analytical biochemistry 240 (2), 155-166, 1996
6521996
Role of arginine in protein refolding, solubilization, and purification
K Tsumoto, M Umetsu, I Kumagai, D Ejima, JS Philo, T Arakawa
Biotechnology progress 20 (5), 1301-1308, 2004
6102004
Mechanisms of protein aggregation
JS Philo, T Arakawa
Current pharmaceutical biotechnology 10 (4), 348-351, 2009
3452009
Is any measurement method optimal for all aggregate sizes and types?
JS Philo
The AAPS journal 8, E564-E571, 2006
3242006
A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions
JS Philo
Analytical biochemistry 279 (2), 151-163, 2000
3152000
An improved function for fitting sedimentation velocity data for low-molecular-weight solutes
JS Philo
Biophysical Journal 72 (1), 435-444, 1997
2781997
Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction
JS Philo, KH Aoki, T Arakawa, LO Narhi, J Wen
Biochemistry 35 (5), 1681-1691, 1996
2681996
The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals
T Arakawa, D Ejima, T Li, JS Philo
Journal of pharmaceutical sciences 99 (4), 1674-1692, 2010
2532010
Improved methods for fitting sedimentation coefficient distributions derived by time-derivative techniques
JS Philo
Analytical biochemistry 354 (2), 238-246, 2006
2402006
Elution of antibodies from a Protein-A column by aqueous arginine solutions
T Arakawa, JS Philo, K Tsumoto, R Yumioka, D Ejima
Protein expression and purification 36 (2), 244-248, 2004
2362004
A critical review of methods for size characterization of non-particulate protein aggregates
JS Philo
Current pharmaceutical biotechnology 10 (4), 359-372, 2009
2342009
Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies
D Ejima, K Tsumoto, H Fukada, R Yumioka, K Nagase, T Arakawa, ...
Proteins: Structure, Function, and Bioinformatics 66 (4), 954-962, 2007
2312007
Conformation of sLex Tetrasaccharide, Free in Solution and Bound to E-, P-, and L-Selectin,
L Poppe, GS Brown, JS Philo, PV Nikrad, BH Shah
Journal of the American Chemical Society 119 (7), 1727-1736, 1997
2291997
Online size-exclusion high-performance liquid chromatography light scattering and differential refractometry methods to determine degree of polymer conjugation to proteins and …
BS Kendrick, BA Kerwin, BS Chang, JS Philo
Analytical biochemistry 299 (2), 136-146, 2001
1492001
Mechanism of photoinhibition of photosynthetic water oxidation by chloride depletion and fluoride substitution: oxidation of a protein residue
M Baumgarten, JS Philo, GC Dismukes
Biochemistry 29 (48), 10814-10822, 1990
1261990
Aggregation analysis of therapeutic proteins, part 1
T Arakawa, JS Philo, D Ejima, K Tsumoto, F Arisaka
BioProcess International 4 (10), 32-42, 2006
1162006
Human Stem Cell Factor Dimer Forms a Complex with Two Molecules of the Extracellular Domain of Its Receptor, Kit (∗)
JS Philo, J Wen, J Wypych, MG Schwartz, EA Mendiaz, KE Langley
Journal of Biological Chemistry 271 (12), 6895-6902, 1996
1151996
Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase
KS Misono, JS Philo, T Arakawa, CM Ogata, Y Qiu, H Ogawa, HS Young
The FEBS journal 278 (11), 1818-1829, 2011
1122011
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
T Horan, J Wen, T Arakawa, N Liu, D Brankow, S Hu, B Ratzkin, JS Philo
Journal of Biological Chemistry 270 (41), 24604-24608, 1995
1051995
High‐sensitivity magnetic susceptometer employing superconducting technology
JS Philo, WM Fairbank
Review of Scientific Instruments 48 (12), 1529-1536, 1977
1041977
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Artikelen 1–20