Christopher Oakes
Christopher Oakes
Assistant Professor, Division of Hematology, Departments of Internal Medicine and Biomedical Informatics, The Ohio State University
Geverifieerd e-mailadres voor osumc.edu - Homepage
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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ...
Nature genetics 48 (3), 253-264, 2016
2392016
Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A
K Arab, YJ Park, AM Lindroth, A Schäfer, C Oakes, D Weichenhan, ...
Molecular cell 55 (4), 604-614, 2014
2352014
Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells
CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler
Developmental biology 307 (2), 368-379, 2007
2312007
Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer
D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ...
Cell reports 8 (3), 798-806, 2014
2132014
Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats
CC Oakes, DJ Smiraglia, C Plass, JM Trasler, B Robaire
Proceedings of the National Academy of Sciences 100 (4), 1775-1780, 2003
1982003
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ...
Nature genetics 49 (7), 1052-1060, 2017
1622017
A unique configuration of genome-wide DNA methylation patterns in the testis
CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler
Proceedings of the National Academy of Sciences 104 (1), 228-233, 2007
1552007
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ...
Cancer discovery 4 (3), 348-361, 2014
1412014
Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB
A Garding, N Bhattacharya, R Claus, M Ruppel, C Tschuch, K Filarsky, ...
PLoS genetics 9 (4), e1003373, 2013
1402013
p53-dependent non-coding RNA networks in chronic lymphocytic leukemia
CJ Blume, A Hotz-Wagenblatt, J Hüllein, L Sellner, A Jethwa, T Stolz, ...
Leukemia 29 (10), 2015
1392015
Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia
R Claus, DM Lucas, S Stilgenbauer, AS Ruppert, L Yu, M Zucknick, ...
Journal of Clinical Oncology 30 (20), 2483, 2012
1272012
Epigenetics in acute myeloid leukemia
C Plass, C Oakes, W Blum, G Marcucci
Seminars in oncology 35 (4), 378-387, 2008
1042008
Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L
S La Salle, CC Oakes, OR Neaga, D Bourc'his, TH Bestor, JM Trasler
BMC developmental biology 7 (1), 1-18, 2007
1032007
Evaluation of a quantitative DNA methylation analysis technique using methylation-sensitive/dependent restriction enzymes and real-time PCR
CC Oakes, S La Salle, B Robaire, JM Trasler
Epigenetics 1 (3), 146-152, 2006
1012006
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ...
Nature genetics 47 (1), 22-30, 2015
1002015
Drug-perturbation-based stratification of blood cancer
S Dietrich, M Oleś, J Lu, L Sellner, S Anders, B Velten, B Wu, J Hüllein, ...
The Journal of clinical investigation 128 (1), 427-445, 2018
872018
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice
J Trasler, L Deng, S Melnyk, I Pogribny, F Hiou-Tim, S Sibani, C Oakes, ...
Carcinogenesis 24 (1), 39-45, 2003
812003
Down‐regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms
B Goeppert, P Schmezer, C Dutruel, C Oakes, M Renner, M Breinig, ...
Hepatology 52 (6), 2023-2033, 2010
792010
High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells
S Oppermann, J Ylanko, Y Shi, S Hariharan, CC Oakes, PM Brauer, ...
Blood, The Journal of the American Society of Hematology 128 (7), 934-947, 2016
782016
Adverse effects of 5-aza-2′-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation
CC Oakes, TLJ Kelly, B Robaire, JM Trasler
Journal of Pharmacology and Experimental Therapeutics 322 (3), 1171-1180, 2007
762007
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