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Peter Cook
Peter Cook
Verified email at exeter.ac.uk
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Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation
SJ Jenkins, D Ruckerl, PC Cook, LH Jones, FD Finkelman, N van Rooijen, ...
Science 332 (6035), 1284-1288, 2011
16072011
CD11c depletion severely disrupts Th2 induction and development in vivo
AT Phythian-Adams, PC Cook, RJ Lundie, LH Jones, KA Smith, TA Barr, ...
Journal of Experimental Medicine 207 (10), 2089-2096, 2010
3132010
The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation
FR Svedberg, SL Brown, MZ Krauss, L Campbell, C Sharpe, M Clausen, ...
Nature immunology 20 (5), 571-580, 2019
1692019
Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo
PC Cook, LH Jones, SJ Jenkins, TA Wynn, JE Allen, AS MacDonald
Proceedings of the National Academy of Sciences 109 (25), 9977-9982, 2012
1462012
Dynamics of colon monocyte and macrophage activation during colitis
GR Jones, CC Bain, T Fenton, A Kelly, S Brown, A Ivens, M Travis, ...
Frontiers in immunology 9, 2764, 2018
1362018
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung
T Fujimori, AM Grabiec, M Kaur, TJ Bell, N Fujino, PC Cook, FR Svedberg, ...
Mucosal immunology 8 (5), 1021-1030, 2015
1212015
The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ …
RA Paveley, SA Aynsley, JD Turner, CD Bourke, SJ Jenkins, PC Cook, ...
International journal for parasitology 41 (13-14), 1335-1345, 2011
1042011
CD4+ CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection
JD Turner, GR Jenkins, KG Hogg, SA Aynsley, RA Paveley, PC Cook, ...
PLoS Negl Trop Dis 5 (8), e1269, 2011
1022011
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
T Furukawa, N van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, ...
Nature Communications 11 (1), 1-16, 2020
942020
Dendritic cells in lung immunopathology
PC Cook, AS MacDonald
Seminars in immunopathology 38 (4), 449-460, 2016
912016
A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells
PC Cook, H Owen, AM Deaton, JG Borger, SL Brown, T Clouaire, ...
Nature communications 6 (1), 1-11, 2015
842015
Pathogenesis of Respiratory Viral and Fungal Coinfections
F Salazar, E Bignell, GD Brown, PC Cook, A Warris
Clinical Microbiology Reviews 35 (1), e00094-21, 2021
832021
Type I interferon is required for T helper (Th) 2 induction by dendritic cells
LM Webb, RJ Lundie, JG Borger, SL Brown, LM Connor, ANR Cartwright, ...
The EMBO journal 36 (16), 2404-2418, 2017
812017
Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells
RA Paveley, SA Aynsley, PC Cook, JD Turner, AP Mountford
PLoS neglected tropical diseases 3 (10), e528, 2009
792009
Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype
VL Morrison, MJ James, K Grzes, P Cook, DG Glass, T Savinko, ...
Nature communications 5, 5359, 2014
642014
Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells
PC Cook, SA Aynsley, JD Turner, GR Jenkins, N Van Rooijen, M Leeto, ...
PLoS pathogens 7 (3), e1001323, 2011
552011
Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma
AM Grabiec, N Denny, JA Doherty, KE Happonen, J Hankinson, ...
Journal of Allergy and Clinical Immunology 140 (4), 1144-1146. e4, 2017
522017
The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function
AJ Bancroft, CW Levy, TA Jowitt, KS Hayes, S Thompson, EA Mckenzie, ...
Nature communications 10 (1), 2344, 2019
502019
Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration
X Zhang, PC Cook, E Zindy, CJ Williams, TA Jowitt, CH Streuli, ...
Nucleic acids research 44 (7), 3031-3044, 2016
402016
Schistosomes in the lung: immunobiology and opportunity
EL Houlder, AH Costain, PC Cook, AS MacDonald
Frontiers in Immunology 12, 1330, 2021
322021
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