The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-β1 MC Hall, DA Young, JG Waters, AD Rowan, A Chantry, DR Edwards, ... Journal of Biological Chemistry 278 (12), 10304-10313, 2003 | 340 | 2003 |
The cysteine proteinases of the pineapple plant. AD Rowan, DJ Buttle, AJ Barrett Biochemical Journal 266 (3), 869, 1990 | 305 | 1990 |
The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin‐1 and oncostatin M: a time‐course study using real‐time quantitative … PJT Koshy, CJ Lundy, AD Rowan, S Porter, DR Edwards, A Hogan, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2002 | 269 | 2002 |
Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines PJ Koshy, N Henderson, C Logan, PF Life, TE Cawston, AD Rowan Annals of the rheumatic diseases 61 (8), 704-713, 2002 | 264 | 2002 |
The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint TE Cawston, VA Curry, CA Summers, IM Clark, GP Riley, PF Life, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1998 | 258 | 1998 |
Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases W Hui, GJ Litherland, MS Elias, GI Kitson, TE Cawston, AD Rowan, ... Annals of the rheumatic diseases 71 (3), 455-462, 2012 | 256 | 2012 |
Rat procathepsin B. Proteolytic processing to the mature form in vitro. AD Rowan, P Mason, L Mach, JS Mort Journal of Biological Chemistry 267 (22), 15993-15999, 1992 | 240 | 1992 |
Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin‐1 on cartilage collagen breakdown AD Rowan, PJT Koshy, WD Shingleton, BA Degnan, JK Heath, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2001 | 190 | 2001 |
The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation HF Bigg, R Wait, AD Rowan, TE Cawston Journal of Biological Chemistry 281 (30), 21082-21095, 2006 | 181 | 2006 |
Activity of matrix metalloproteinase‐9 against native collagen types I and III HF Bigg, AD Rowan, MD Barker, TE Cawston The FEBS journal 274 (5), 1246-1255, 2007 | 179 | 2007 |
Stem bromelain: amino acid sequence and implications for weak binding of cystatin A Ritonja, AD Rowan, DJ Buttle, ND Rawlings, V Turk, AJ Barrett FEBS letters 247 (2), 419-424, 1989 | 176 | 1989 |
An association between the CTLA4 exon 1 polymorphism and early rheumatoid arthritis with autoimmune endocrinopathies B Vaidya, SHS Pearce, S Charlton, N Marshall, AD Rowan, ID Griffiths, ... Rheumatology 41 (2), 180-183, 2002 | 169 | 2002 |
Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage W Hui, DA Young, AD Rowan, X Xu, TE Cawston, CJ Proctor Annals of the rheumatic diseases 75 (2), 449-458, 2016 | 163 | 2016 |
Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis HE Barksby, JM Milner, AM Patterson, NJ Peake, W Hui, T Robson, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 160 | 2006 |
Oncostatin M in combination with tumor necrosis factor α induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo W Hui, AD Rowan, CD Richards, TE Cawston Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 149 | 2003 |
The regulation of MMPs and TIMPs in cartilage turnover T Cawston, C Billington, C Cleaver, S Elliott, W Hui, P Koshy, ... Annals of the New York Academy of Sciences 878 (1), 120-129, 1999 | 141 | 1999 |
Interleukin‐1 in combination with oncostatin M up‐regulates multiple genes in chondrocytes: implications for cartilage destruction and repair HE Barksby, W Hui, I Wappler, HH Peters, JM Milner, CD Richards, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 139 | 2006 |
[38] Pineapple cysteine endopeptidases AD Rowan, DJ Buttle Methods in enzymology 244, 555-568, 1994 | 139 | 1994 |
cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular … C Bui, MJ Barter, JL Scott, Y Xu, M Galler, LN Reynard, AD Rowan, ... The FASEB Journal 26 (7), 3000-3011, 2012 | 126 | 2012 |
Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC) J Zheng, FL van de Veerdonk, KL Crossland, SP Smeekens, CM Chan, ... European journal of immunology 45 (10), 2834-2846, 2015 | 123 | 2015 |