Jan Van den Bossche
Jan Van den Bossche
Principal Investigator, VU University Medical Center Amsterdam
Geverifieerd e-mailadres voor vumc.nl - Homepage
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Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity
K Movahedi, M Guilliams, J Van den Bossche, R Van den Bergh, ...
Blood 111 (8), 4233-4244, 2008
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes
K Movahedi, D Laoui, C Gysemans, M Baeten, G Stangé, ...
Cancer research 70 (14), 5728-5739, 2010
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
D Laoui, K Movahedi, E Van Overmeire, J Van den Bossche, E Schouppe, ...
International Journal of Developmental Biology 55 (7-8-9), 861-867, 2011
Macrophage immunometabolism: where are we (going)?
J Van den Bossche, LA O’Neill, D Menon
Trends in immunology 38 (6), 395-406, 2017
Mitochondrial dysfunction prevents repolarization of inflammatory macrophages
J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ...
Cell reports 17 (3), 684-696, 2016
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans
FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ...
Circulation 134 (8), 611-624, 2016
Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs
J Van den Bossche, B Malissen, A Mantovani, P De Baetselier, ...
Blood 119 (7), 1623-1633, 2012
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
J Van den Bossche, P Bogaert, J Van Hengel, CJ Guérin, G Berx, ...
Blood 114 (21), 4664-4674, 2009
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions
MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ...
EMBO molecular medicine 6 (9), 1124-1132, 2014
Pivotal Advance: Arginase‐1‐independent polyamine production stimulates the expression of IL‐4‐induced alternatively activated macrophage markers while inhibiting LPS‐induced …
J Van den Bossche, WH Lamers, ES Koehler, JMC Geuns, L Alhonen, ...
Journal of leukocyte biology 91 (5), 685-699, 2012
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality
MR Boon, SAA van den Berg, Y Wang, J van den Bossche, ...
PLoS One 8 (9), e74083, 2013
Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site
D Laoui, E Van Overmeire, K Movahedi, J Van den Bossche, E Schouppe, ...
Immunobiology 216 (11), 1192-1202, 2011
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia
SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ...
European heart journal 38 (20), 1584-1593, 2017
Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis
J Van den Bossche, J Baardman, MPJ de Winther
JoVE (Journal of Visualized Experiments), e53424, 2015
Macrophage polarization: the epigenetic point of view
J Van den Bossche, AE Neele, MA Hoeksema, MPJ De Winther
Current opinion in lipidology 25 (5), 367-373, 2014
Macrophages, PPARs, and cancer
JA Van Ginderachter, K Movahedi, J Van den Bossche, P De Baetselier
PPAR research 2008, 2008
Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis
AE Neele, J Van den Bossche, MA Hoeksema, MPJ De Winther
European journal of pharmacology 763, 79-89, 2015
Inhibiting epigenetic enzymes to improve atherogenic macrophage functions
J Van den Bossche, AE Neele, MA Hoeksema, F De Heij, MCS Boshuizen, ...
Biochemical and biophysical research communications 455 (3-4), 396-402, 2014
IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment
MA Hoeksema, BP Scicluna, MCS Boshuizen, S Van Der Velden, ...
The Journal of Immunology 194 (8), 3909-3916, 2015
Metabolic–epigenetic crosstalk in macrophage activation
J Baardman, I Licht, MPJ De Winther, J Van den Bossche
Epigenomics 7 (7), 1155-1164, 2015
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Artikelen 1–20