Briefly bound to activate: transient binding of a second catalytic magnesium activates the structure and dynamics of CDK2 kinase for catalysis ZQ Bao, DM Jacobsen, MA Young Structure 19 (5), 675-690, 2011 | 108 | 2011 |
Price to be paid for two-metal catalysis: magnesium ions that accelerate chemistry unavoidably limit product release from a protein kinase DM Jacobsen, ZQ Bao, P O’Brien, CL Brooks III, MA Young Journal of the American Chemical Society 134 (37), 15357-15370, 2012 | 73 | 2012 |
ChromoScan: a scan statistic application for identifying chromosomal regions in genomic studies YV Sun, DM Jacobsen, SLR Kardia Bioinformatics 22 (23), 2945-2947, 2006 | 23 | 2006 |
Disruption of magnesium regulation in the crab Cancer productus exposed to chlorinated seawater G Roesijadi, DM Jacobsen, JR Bridge, EA Crecelius Marine Environmental Research 2 (1), 71-84, 1979 | 13 | 1979 |
Fast implementation of a scan statistic for identifying chromosomal patterns of genome wide association studies YV Sun, DM Jacobsen, ST Turner, E Boerwinkle, SLR Kardia Computational statistics & data analysis 53 (5), 1794-1801, 2009 | 10 | 2009 |
KGraph: a system for visualizing and evaluating complex genetic associations RJ Kelly, DM Jacobsen, YV Sun, JA Smith, SLR Kardia Bioinformatics 23 (2), 249-251, 2007 | 10 | 2007 |
Brooks, r., Charles L; Young, MA, Price to Be Paid for Two-Metal Catalysis: Magnesium Ions That Accelerate Chemistry Unavoidably Limit Product Release from a Protein Kinase DM Jacobsen, ZQ Bao, P O'Brien J Am Chem Soc 134, 15357-15370, 2012 | 5 | 2012 |
Allosteric Regulation of Protein Kinase Enzymes via an Electrostatic Switch that Modulates Active Site Dynamics MA Young, DM Jacobsen, ZQ Bao Biophysical Journal 106 (2), 651a, 2014 | | 2014 |
Dual Role of Magnesium Ions in Active pCDK2/Cyclin: Essential Activator of Kinase Activity and Partial Inhibitor of Product Release DM Jacobsen, ZQ Bao, CL Brooks, MA Young Biophysical Journal 102 (3), 271a, 2012 | | 2012 |
An investigation of the roles of magnesium ions in the catalytic cycle of the protein kinase CDK2: A molecular link between allosteric activation and catalytic activity DM Jacobsen University of Michigan, 2012 | | 2012 |
A fast implementation of scan statistic for identifying chromosomal patterns of genome wide association studies YV Sun, DM Jacobsen, ST Turner, KR Bailey, E Boerwinkle, SLR Kardia GENETIC EPIDEMIOLOGY 31 (6), 612-613, 2007 | | 2007 |
KGraph: Visualizing and evaluating complex genetic associations RJ Kelly, DM Jacobsen, YV Sun, JA Smith, SLR Kardia GENETIC EPIDEMIOLOGY 31 (5), 478-478, 2007 | | 2007 |
Wednesday, February 19, 2014 651a MA Young, DM Jacobsen, ZQ Bao | | |
A price to be paid for two-metal catalysis: Magnesium ions that accelerate chemistry unavoidably limit product release from CDK2 kinase. DM Jacobsen, ZQ Bao, P O’Brien, CLB III, MA Young | | |
Supplemental Information Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis ZQ Bao, DM Jacobsen, MA Young | | |