George Vassiliou
George Vassiliou
Faculty, Wellcome Trust Sanger Institute and Wellcome-MRC Cambridge Stem Cell Institute
Verified email at sanger.ac.uk - Homepage
Title
Cited by
Cited by
Year
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
EJ Baxter, LM Scott, PJ Campbell, C East, N Fourouclas, S Swanton, ...
The Lancet 365 (9464), 1054-1061, 2005
38562005
Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study
PJ Campbell, LM Scott, G Buck, K Wheatley, CL East, JT Marsden, A Duffy, ...
The Lancet 366 (9501), 1945-1953, 2005
7742005
Effect of mutation order on myeloproliferative neoplasms
CA Ortmann, DG Kent, J Nangalia, Y Silber, DC Wedge, J Grinfeld, ...
New England Journal of Medicine 372 (7), 601-612, 2015
3532015
Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis
T McKerrell, N Park, T Moreno, CS Grove, H Ponstingl, J Stephens, ...
Cell reports 10 (8), 1239-1245, 2015
3352015
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
I Barbieri, K Tzelepis, L Pandolfini, J Shi, G Millßn-Zambrano, SC Robson, ...
Nature 552 (7683), 126-131, 2017
2862017
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
2732016
Prediction of acute myeloid leukaemia risk in healthy individuals
S Abelson, G Collord, SWK Ng, O Weissbrod, NM Cohen, E Niemeyer, ...
Nature 559 (7714), 400-404, 2018
2522018
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
Elife 3, e02935, 2014
2122014
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice
R Rad, L Rad, W Wang, J Cadinanos, G Vassiliou, S Rice, LS Campos, ...
Science 330 (6007), 1104-1107, 2010
2102010
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
GS Vassiliou, JL Cooper, R Rad, J Li, S Rice, A Uren, L Rad, P Ellis, ...
Nature genetics 43 (5), 470-475, 2011
1932011
Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions
BJP Huntly, F Guilhot, AG Reid, G Vassiliou, E Hennig, C Franke, J Byrne, ...
Blood 102 (6), 2205-2212, 2003
1542003
A genetic progression model of BrafV600E-induced intestinal tumorigenesis reveals targets for therapeutic intervention
R Rad, J Cadi˝anos, L Rad, I Varela, A Strong, L Kriegl, ...
Cancer cell 24 (1), 15-29, 2013
1472013
Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?
CS Grove, GS Vassiliou
Disease models & mechanisms 7 (8), 941-951, 2014
1342014
CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice
J Weber, R Íllinger, M Friedrich, U Ehmer, M Barenboim, K Steiger, I Heid, ...
Proceedings of the National Academy of Sciences 112 (45), 13982-13987, 2015
1302015
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia
MA Dawson, EJ Gudgin, SJ Horton, G Giotopoulos, E Meduri, S Robson, ...
Leukemia 28 (2), 311-320, 2014
1302014
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
S Mueller, T Engleitner, R Maresch, M Zukowska, S Lange, ...
Nature 554 (7690), 62-68, 2018
1282018
Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice
OM Dovey, CT Foster, N Conte, SA Edwards, JM Edwards, R Singh, ...
Blood, The Journal of the American Society of Hematology 121 (8), 1335-1344, 2013
1232013
Guidance for laboratories performing molecular pathology for cancer patients
IA Cree, Z Deans, MJL Ligtenberg, N Normanno, A Edsj÷, E Rouleau, ...
Journal of clinical pathology 67 (11), 923-931, 2014
1182014
KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype
A Clipson, M Wang, L De Leval, M Ashton-Key, A Wotherspoon, ...
Leukemia 29 (5), 1177-1185, 2015
1142015
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice
R Maresch, S Mueller, C Veltkamp, R Íllinger, M Friedrich, I Heid, ...
Nature communications 7 (1), 1-13, 2016
1122016
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