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Amit Upadhyay
Amit Upadhyay
Research Assistant Professor, Emory University
Geverifieerd e-mailadres voor emory.edu
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
PS Arunachalam, F Wimmers, CKP Mok, RAPM Perera, M Scott, T Hagan, ...
Science 369 (6508), 1210-1220, 2020
10592020
Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans
T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ...
Cell 178 (6), 1313-1328. e13, 2019
4532019
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ...
Cell 177 (5), 1153-1171. e28, 2019
3272019
Type I and type III interferons restrict SARS-CoV-2 infection of human airway epithelial cultures
A Vanderheiden, P Ralfs, T Chirkova, AA Upadhyay, MG Zimmerman, ...
Journal of virology 94 (19), 10.1128/jvi. 00985-20, 2020
2912020
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo
CC Nixon, M Mavigner, GC Sampey, AD Brooks, RA Spagnuolo, ...
Nature 578 (7793), 160-165, 2020
2362020
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
TN Hoang, M Pino, AK Boddapati, EG Viox, CE Starke, AA Upadhyay, ...
Cell 184 (2), 460-475. e21, 2021
1772021
Cache domains that are homologous to, but different from PAS domains comprise the largest superfamily of extracellular sensors in prokaryotes
AA Upadhyay, AD Fleetwood, O Adebali, RD Finn, IB Zhulin
PLoS computational biology 12 (4), e1004862, 2016
1672016
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen
C Havenar-Daughton, A Sarkar, DW Kulp, L Toy, X Hu, I Deresa, ...
Science translational medicine 10 (448), eaat0381, 2018
1182018
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs
NK Routhu, N Cheedarla, S Gangadhara, VS Bollimpelli, AK Boddapati, ...
Immunity 54 (3), 542-556. e9, 2021
782021
West Nile virus-inclusive single-cell RNA sequencing reveals heterogeneity in the type I interferon response within single cells
JT O’Neal, AA Upadhyay, A Wolabaugh, NB Patel, SE Bosinger, ...
Journal of virology 93 (6), 10.1128/jvi. 01778-18, 2019
562019
BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data
AA Upadhyay, RC Kauffman, AN Wolabaugh, A Cho, NB Patel, SM Reiss, ...
Genome medicine 10, 1-18, 2018
562018
Rapid germinal center and antibody responses in non-human primates after a single nanoparticle vaccine immunization
C Havenar-Daughton, DG Carnathan, AV Boopathy, AA Upadhyay, ...
Cell reports 29 (7), 1756-1766. e8, 2019
502019
How bacterial chemoreceptors evolve novel ligand specificities
JA Gavira, VM Gumerov, M Rico-Jiménez, M Petukh, AA Upadhyay, ...
MBio 11 (1), 10.1128/mbio. 03066-19, 2020
492020
Sequence, structure, and evolution of cellulases in glycoside hydrolase family 48
LO Sukharnikov, M Alahuhta, R Brunecky, A Upadhyay, ME Himmel, ...
Journal of Biological Chemistry 287 (49), 41068-41077, 2012
472012
Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates
J Corry, G Kettenburg, AA Upadhyay, M Wallace, MM Marti, ...
PLoS Pathogens 18 (3), e1010395, 2022
302022
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
J Harper, N Huot, L Micci, G Tharp, C King, P Rascle, N Shenvi, H Wang, ...
Nature Communications 12 (1), 2866, 2021
282021
From structure to sequence: antibody discovery using cryoEM
A Antanasijevic, CA Bowman, RN Kirchdoerfer, CA Cottrell, G Ozorowski, ...
Science Advances 8 (3), eabk2039, 2022
182022
Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion
E Salinas, M Boisvert, AA Upadhyay, N Bédard, SA Nelson, J Bruneau, ...
The Journal of Clinical Investigation 131 (2), 2021
172021
Clinical and whole genome characterization of SARS-CoV-2 in India
R Muttineni, N Kammili, TC Bingi, R Rao M, K Putty, PS Dholaniya, ...
PLoS One 16 (2), e0246173, 2021
132021
TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
AA Upadhyay, EG Viox, TN Hoang, AK Boddapati, M Pino, MYH Lee, ...
Nature Communications 14 (1), 1914, 2023
122023
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Artikelen 1–20