| FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation MM Gaschler, AA Andia, H Liu, JM Csuka, B Hurlocker, CA Vaiana, ... Nature chemical biology 14 (5), 507-515, 2018 | 555 | 2018 |
| Imidazole ketone erastin induces ferroptosis and slows tumor growth in a mouse lymphoma model Y Zhang, H Tan, JD Daniels, F Zandkarimi, H Liu, LM Brown, K Uchida, ... Cell chemical biology 26 (5), 623-633. e9, 2019 | 462 | 2019 |
| Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors S Iketani, F Forouhar, H Liu, SJ Hong, FY Lin, MS Nair, A Zask, Y Huang, ... Nature communications 12 (1), 2016, 2021 | 99 | 2021 |
| Targeting dependency on the GPX4 lipid peroxide repair pathway for cancer therapy H Liu, SL Schreiber, BR Stockwell Biochemistry 57 (14), 2059-2060, 2018 | 78 | 2018 |
| Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19 H Liu, S Iketani, A Zask, N Khanizeman, E Bednarova, F Forouhar, ... Nature communications 13 (1), 1891, 2022 | 51 | 2022 |
| Characterization of a patient-derived variant of GPX4 for precision therapy H Liu, F Forouhar, T Seibt, R Saneto, K Wigby, J Friedman, X Xia, ... Nature chemical biology 18 (1), 91-100, 2022 | 47 | 2022 |
| Inhibitors of coronavirus 3CL proteases protect cells from protease-mediated cytotoxicity SJ Resnick, S Iketani, SJ Hong, A Zask, H Liu, S Kim, S Melore, FY Lin, ... Journal of Virology 95 (14), 10.1128/jvi. 02374-20, 2021 | 30 | 2021 |
| Small-molecule allosteric inhibitors of GPX4 H Liu, F Forouhar, AJ Lin, Q Wang, V Polychronidou, RK Soni, X Xia, ... Cell chemical biology 29 (12), 1680-1693. e9, 2022 | 25 | 2022 |
| A simplified cell-based assay to identify coronavirus 3CL protease inhibitors SJ Resnick, S Iketani, SJ Hong, A Zask, H Liu, S Kim, S Melore, MS Nair, ... Biorxiv, 2020 | 8 | 2020 |
| APR-246 increases tumor antigenicity independent of p53 J Michels, D Venkatesh, C Liu, S Budhu, H Zhong, MM George, D Thach, ... Life Science Alliance 7 (1), 2024 | 1 | 2024 |
| Gpx4 compounds and compositions and methods of treatment using same BR Stockwell, H LIU, F FOROUHAR, Q Wang US Patent US20230167058A1, 2023 | | 2023 |
| Gpx4 inhibitors and uses thereof BR Stockwell, H LIU, F FOROUHAR, X XIA, A LIN, Q Wang WO Patent WO2023039510A1, 2023 | | 2023 |
| Gpx4 compounds and compositions and methods of treatment using same BR Stockwell, H LIU, F FOROUHAR, Q Wang EP Patent EP4117642A1, 2023 | | 2023 |
| Probing Diseases using Small Molecules H Liu Columbia University, 2021 | | 2021 |
Brent R. StockwellProfessor of Biological Sciences and ChemistryAdresse e-mail validée de columbia.edu
