Norman Sachs
Norman Sachs
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A living biobank of breast cancer organoids captures disease heterogeneity
N Sachs, J de Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ...
Cell 172 (1), 373-386. e10, 2018
Designer matrices for intestinal stem cell and organoid culture
N Gjorevski, N Sachs, A Manfrin, S Giger, ME Bragina, P Ordóñez-Morán, ...
Nature 539 (7630), 560-564, 2016
Sequential cancer mutations in cultured human intestinal stem cells
J Drost, RH Van Jaarsveld, B Ponsioen, C Zimberlin, R Van Boxtel, ...
Nature 521 (7550), 43-47, 2015
Generation of tumor-reactive T cells by co-culture of peripheral blood lymphocytes and tumor organoids
KK Dijkstra, CM Cattaneo, F Weeber, M Chalabi, J van de Haar, ...
Cell 174 (6), 1586-1598. e12, 2018
Long‐term expanding human airway organoids for disease modeling
N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ...
The EMBO journal 38 (4), e100300, 2019
Identification of multipotent luminal progenitor cells in human prostate organoid cultures
WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ...
Cell 159 (1), 163-175, 2014
Organoid cultures for the analysis of cancer phenotypes
N Sachs, H Clevers
Current opinion in genetics & development 24, 68-73, 2014
Modelling Cryptosporidium infection in human small intestinal and lung organoids
I Heo, D Dutta, DA Schaefer, N Iakobachvili, B Artegiani, N Sachs, ...
Nature microbiology 3 (7), 814-823, 2018
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon
N Sasaki, N Sachs, K Wiebrands, SIJ Ellenbroek, A Fumagalli, ...
Proceedings of the National Academy of Sciences 113 (37), E5399-E5407, 2016
Kidney failure in mice lacking the tetraspanin CD151
N Sachs, M Kreft, MA van den Bergh Weerman, AJ Beynon, TA Peters, ...
The Journal of cell biology 175 (1), 33-39, 2006
Differentiated human airway organoids to assess infectivity of emerging influenza virus
J Zhou, C Li, N Sachs, MC Chiu, BHY Wong, H Chu, VKM Poon, D Wang, ...
Proceedings of the National Academy of Sciences 115 (26), 6822-6827, 2018
Integrin α3β1 inhibits directional migration and wound re-epithelialization in the skin
C Margadant, K Raymond, M Kreft, N Sachs, H Janssen, A Sonnenberg
Journal of Cell Science 122 (2), 278-288, 2009
Cell–matrix adhesion of podocytes in physiology and disease
N Sachs, A Sonnenberg
Nature Reviews Nephrology 9 (4), 200-210, 2013
Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages
JM Rosenbluth, RCJ Schackmann, GK Gray, LM Selfors, CMC Li, ...
Nature communications 11 (1), 1711, 2020
Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome
N Nicolaou, C Margadant, SH Kevelam, MR Lilien, MJS Oosterveld, ...
The Journal of clinical investigation 122 (12), 4375-4387, 2012
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells
M Yañez-Mó, O Barreiro, P Gonzalo, A Batista, D Megías, L Genís, ...
Blood, The Journal of the American Society of Hematology 112 (8), 3217-3226, 2008
BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance
AA Duarte, E Gogola, N Sachs, M Barazas, S Annunziato, J R De Ruiter, ...
Nature methods 15 (2), 134-140, 2018
Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels
N Sachs, Y Tsukamoto, P Kujala, PJ Peters, H Clevers
Development 144 (6), 1107-1112, 2017
Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures
KPY Hui, RHH Ching, SKH Chan, JM Nicholls, N Sachs, H Clevers, ...
The Lancet Respiratory Medicine 6 (11), 846-854, 2018
On the biomechanics of stem cell niche formation in the gut–modelling growing organoids
P Buske, J Przybilla, M Loeffler, N Sachs, T Sato, H Clevers, J Galle
The FEBS journal 279 (18), 3475-3487, 2012
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