Follow
Daniel Kastner
Daniel Kastner
Scientific Director, National Human Genome Research Institute, NIH
Verified email at mail.nih.gov
Title
Cited by
Cited by
Year
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muņoz-Planillo, ...
Nature medicine 21 (3), 248-255, 2015
22402015
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
AB Begovich, VEH Carlton, LA Honigberg, SJ Schrodi, AP Chokkalingam, ...
The American Journal of Human Genetics 75 (2), 330-337, 2004
18512004
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ...
Cell 97 (1), 133-144, 1999
16011999
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ...
Nature genetics 42 (6), 508-514, 2010
15432010
STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus
EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ...
New England Journal of Medicine 357 (10), 977-986, 2007
12882007
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
SL Masters, A Simon, I Aksentijevich, DL Kastner
Annual review of immunology 27, 621-668, 2009
12842009
Activated STING in a vascular and pulmonary syndrome
Y Liu, AA Jesus, B Marrero, D Yang, SE Ramsey, ...
New England Journal of Medicine 371 (6), 507-518, 2014
11902014
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition
R Goldbach-Mansky, NJ Dailey, SW Canna, A Gelabert, J Jones, BI Rubin, ...
New England Journal of Medicine 355 (6), 581-592, 2006
10242006
TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study
RM Plenge, M Seielstad, L Padyukov, AT Lee, EF Remmers, B Ding, ...
New England Journal of Medicine 357 (12), 1199-1209, 2007
10192007
An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist
I Aksentijevich, SL Masters, PJ Ferguson, P Dancey, J Frenkel, ...
New England Journal of Medicine 360 (23), 2426-2437, 2009
10172009
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
GS Lee, N Subramanian, AI Kim, I Aksentijevich, R Goldbach-Mansky, ...
Nature 492 (7427), 123-127, 2012
9902012
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
AC Bulua, A Simon, R Maddipati, M Pelletier, H Park, KY Kim, MN Sack, ...
Journal of Experimental Medicine 208 (3), 519-533, 2011
9562011
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal‐onset multisystem inflammatory disease (NOMID …
I Aksentijevich, M Nowak, M Mallah, JJ Chae, WT Watford, SR Hofmann, ...
Arthritis & Rheumatism 46 (12), 3340-3348, 2002
8292002
Early-onset stroke and vasculopathy associated with mutations in ADA2
Q Zhou, D Yang, AK Ombrello, AV Zavialov, C Toro, AV Zavialov, ...
New England Journal of Medicine 370 (10), 911-920, 2014
7882014
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behįet's disease
EF Remmers, F Cosan, Y Kirino, MJ Ombrello, N Abaci, C Satorius, JM Le, ...
Nature genetics 42 (8), 698-702, 2010
7462010
Replication of putative candidate-gene associations with rheumatoid arthritis in> 4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4 …
RM Plenge, L Padyukov, EF Remmers, S Purcell, AT Lee, EW Karlson, ...
The American Journal of Human Genetics 77 (6), 1044-1060, 2005
7132005
The B30. 2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production
JJ Chae, G Wood, SL Masters, K Richard, G Park, BJ Smith, DL Kastner
Proceedings of the National Academy of Sciences 103 (26), 9982-9987, 2006
7052006
A guiding map for inflammation
MG Netea, F Balkwill, M Chonchol, F Cominelli, MY Donath, ...
Nature immunology 18 (8), 826-831, 2017
6412017
Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease
DB Beck, MA Ferrada, KA Sikora, AK Ombrello, JC Collins, W Pei, ...
New England Journal of Medicine 383 (27), 2628-2638, 2020
6402020
Common variants at CD40 and other loci confer risk of rheumatoid arthritis
S Raychaudhuri, EF Remmers, AT Lee, R Hackett, C Guiducci, NP Burtt, ...
Nature genetics 40 (10), 1216-1223, 2008
6082008
The system can't perform the operation now. Try again later.
Articles 1–20