| DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells JJ Trowbridge, JW Snow, J Kim, SH Orkin Cell stem cell 5 (4), 442-449, 2009 | 416 | 2009 |
| Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation JJ Trowbridge, A Xenocostas, RT Moon, M Bhatia Nature medicine 12 (1), 89-98, 2006 | 304 | 2006 |
| Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease A Burberry, N Suzuki, JY Wang, R Moccia, DA Mordes, MH Stewart, ... Science translational medicine 8 (347), 347ra93-347ra93, 2016 | 281 | 2016 |
| Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A J Xu, DE Bauer, MA Kerenyi, TD Vo, S Hou, YJ Hsu, H Yao, JJ Trowbridge, ... Proceedings of the National Academy of Sciences 110 (16), 6518-6523, 2013 | 257 | 2013 |
| Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration JJ Trowbridge, MP Scott, M Bhatia Proceedings of the National Academy of Sciences 103 (38), 14134-14139, 2006 | 233 | 2006 |
| Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains JJ Trowbridge, AU Sinha, N Zhu, M Li, SA Armstrong, SH Orkin Genes & development 26 (4), 344-349, 2012 | 146 | 2012 |
| Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS JJ Trowbridge, DT Starczynowski Journal of Experimental Medicine 218 (7), e20201544, 2021 | 106 | 2021 |
| Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging K Young, E Eudy, R Bell, MA Loberg, T Stearns, D Sharma, L Velten, ... Cell stem cell 28 (8), 1473-1482. e7, 2021 | 99 | 2021 |
| The lethal sex gap: COVID-19 EJ Márquez, J Trowbridge, GA Kuchel, J Banchereau, D Ucar Immunity & Ageing 17, 1-8, 2020 | 96 | 2020 |
| Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis MA Loberg, RK Bell, LO Goodwin, E Eudy, LA Miles, JM SanMiguel, ... Leukemia 33 (7), 1635-1649, 2019 | 94 | 2019 |
| Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging K Young, S Borikar, R Bell, L Kuffler, V Philip, JJ Trowbridge Journal of Experimental Medicine 213 (11), 2259-2267, 2016 | 90 | 2016 |
| Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior F Shojaei, J Trowbridge, L Gallacher, L Yuefei, D Goodale, F Karanu, ... Developmental cell 8 (5), 651-663, 2005 | 82 | 2005 |
| Context-dependent function of “GATA switch” sites in vivo JW Snow, JJ Trowbridge, KD Johnson, T Fujiwara, NE Emambokus, ... Blood, The Journal of the American Society of Hematology 117 (18), 4769-4772, 2011 | 64 | 2011 |
| A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2 JW Snow, JJ Trowbridge, T Fujiwara, NE Emambokus, JA Grass, ... PLoS genetics 6 (9), e1001103, 2010 | 64 | 2010 |
| Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells J George, A Uyar, K Young, L Kuffler, K Waldron-Francis, E Marquez, ... Nature communications 7 (1), 12166, 2016 | 58 | 2016 |
| A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis M Rosu-Myles, E Stewart, J Trowbridge, CY Ito, P Zandstra, M Bhatia Journal of cell science 118 (19), 4343-4352, 2005 | 49 | 2005 |
| Hand in hand: intrinsic and extrinsic drivers of aging and clonal hematopoiesis JM SanMiguel, K Young, JJ Trowbridge Experimental hematology 91, 1-9, 2020 | 47 | 2020 |
| Dnmt3a silences hematopoietic stem cell self-renewal JJ Trowbridge, SH Orkin Nature genetics 44 (1), 13-14, 2012 | 47 | 2012 |
| Actinomycin D targets NPM1c-primed mitochondria to restore PML-driven senescence in AML therapy HC Wu, D Rérolle, C Berthier, R Hleihel, T Sakamoto, S Quentin, ... Cancer discovery 11 (12), 3198-3213, 2021 | 43 | 2021 |
| Hematopoietic stem cell biology: too much of a Wnt thing JJ Trowbridge, RT Moon, M Bhatia Nature immunology 7 (10), 1021-1023, 2006 | 43 | 2006 |
