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Omozuanvbo Aisiku
Omozuanvbo Aisiku
Beth Israel Deaconess Medical Center
Verified email at bidmc.harvard.edu
Title
Cited by
Cited by
Year
Primary human lung alveolus‐on‐a‐chip model of intravascular thrombosis for assessment of therapeutics
A Jain, R Barrile, AD van der Meer, A Mammoto, T Mammoto, ...
Clinical pharmacology & therapeutics 103 (2), 332-340, 2018
2832018
Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar
O Aisiku, CG Peters, K De Ceunynck, CC Ghosh, JR Dilks, ...
Blood, The Journal of the American Society of Hematology 125 (12), 1976-1985, 2015
952015
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury
K De Ceunynck, CG Peters, A Jain, SJ Higgins, O Aisiku, JL Fitch-Tewfik, ...
Proceedings of the National Academy of Sciences 115 (5), E982-E991, 2018
722018
VAMP-7 links granule exocytosis to actin reorganization during platelet activation
S Koseoglu, CG Peters, JL Fitch-Tewfik, O Aisiku, L Danglot, T Galli, ...
Blood, The Journal of the American Society of Hematology 126 (5), 651-660, 2015
712015
Discovery of 1, 3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor
C Dockendorff, O Aisiku, L VerPlank, JR Dilks, DA Smith, SF Gunnink, ...
ACS Medicinal Chemistry Letters 3 (3), 232-237, 2012
592012
Identification of a novel binding partner of phospholipase Cβ1: translin-associated factor X
OR Aisiku, LW Runnels, S Scarlata
PloS one 5 (11), e15001, 2010
562010
Protein kinase C phosphorylation of PLCβ1 regulates its cellular localization
O Aisiku, L Dowal, S Scarlata
Archives of biochemistry and biophysics 509 (2), 186-190, 2011
342011
Complement activation in trauma patients alters platelet function
G Atefi, O Aisiku, N Shapiro, C Hauser, J Dalle Lucca, R Flaumenhaft, ...
Shock 46 (3S), 83-88, 2016
332016
A chemical APC mimetic protects endothelium from thromboinflammatory injury
KEP De Ceunynck, CG Peters, SA Chaudhry, A Jain, SJ Higgins, O Aisiku, ...
Blood 128 (22), 3835, 2016
42016
Reverse Translation
A Jain, R Barrile, A van der Meer, A Mammoto, T Mammoto, K Ceunynck, ...
CLINICAL PHARMACOLOGY AND THERAPEUTICS-ST LOUIS- 103 (2), 332-340, 2018
2018
Analysis of Mechanism of a Novel Drug Candidate using an Organ-level Functional Microdevice that Reconstitutes Human Pulmonary Thrombosis
A Jain, R Barrile, O Aisiku, KD Ceunynck, AD van der Meer, MA Otieno, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 36 (suppl_1), A342-A342, 2016
2016
VAMP-7 links granule exocytosis to platelet spreading
S Koseoglu, JL Fitch-Tewfik, CG Peters, O Aisiku, L Danglot, T Galli, ...
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 61-61, 2015
2015
A class of biased PAR1 agonists that stimulate cytoprotective signaling in endothelial cells
OR Aisiku, CG Peters, KD Ceunyck, J Fitch-Tewfik, JR Dilks, ...
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 33-33, 2015
2015
Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells
OR Aisiku, CG Peters, S Gunnink, JR Dilks, C Dockendorff, R Flaumenhaft
Blood 122 (21), 23, 2013
2013
Parmodulins act at PAR1 to stimulate cytoprotective genetic program in endothelial cells
OR Aisiku, CG Peters, JR Dilks, JL Fitch-Tewfik, C Dockendorff, ...
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 202-203, 2013
2013
Parmodulins target the intracellular side of PAR1 to selectively interfere with Gaq but not Ga12/13 signaling and block thrombus formation, but not hemostasis
OR Aisiku, CG Peters, JR Dilks, S Gunnink, C Dockendorff, DA Smith, ...
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 106-107, 2013
2013
Acyl-Protein Thioesterase 1 Functions in Palmitoylation/Depalmitoylation Cycles of G Proteins and Regulates Platelet Activation
LM Dowal, JR Dilks, NA Fadel, OR Aisiku, G Merrill-Skoloff, ...
Blood, The Journal of the American Society of Hematology 120 (21), 1062-1062, 2012
2012
An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo
OR Aisiku, C Dockendorff, SF Gunnick, DA Smith, JR Dilks, LM Dowal, ...
Blood 118 (21), 1138, 2011
2011
The Identification of a Novel Binding Partner for Phospholipase Cβ1, Translin-Associated Factor X: A Link to RNA Interference
OR Aisiku
State University of New York at Stony Brook, 2010
2010
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Articles 1–19